Frontotemporal Lobar Degeneration clinical trials

The registry lists 47 studies for Frontotemporal Lobar Degeneration across more than 10 countries. 11 are recruiting or about to start. 12 of them are mainly about Frontotemporal Lobar Degeneration (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 2 narrower conditions too, such as Frontotemporal Dementia: 238 studies, 81 open.

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Status

Completed: 26
Recruiting: 8
Active, not recruiting: 4
Not yet recruiting: 3
Status unknown: 3
Withdrawn: 2

Phase

Phase 2: 4
Phase 4: 3
Phase 1: 1
Phase 3: 1

Where

United States: 22
France: 11
Canada: 6
Italy: 4
Netherlands: 1
Belgium: 1

Who runs them

University of California, San Francisco (6) · Assistance Publique - Hôpitaux de Paris (4) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · University Health Network, Toronto (2) · BioSensics (2) · Columbia University (2) · Nantes University Hospital (2) · National Institute of Mental Health (NIMH) (2)

What is being tested here

Drugs under test in Frontotemporal Lobar Degeneration studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
NIO752	1	0	1
PI-2620	1	1	1
Rotigotine	0	0	1
Tolcapone	0	0	1
Flortaucipir	0	0	1
Davunetide	0	0	1
Citalopram	0	0	1
Acetaminophen	0	0	1
Buprenorphine	0	0	1
Memantine	0	0	1

Coming up

1phase 3 study under way

6studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 6

Dec 2026The Skin as a Window to the Central Nervous System in Frontotempolar Lombar Degeneration · Nantes University Hospital
Feb 2027Neurofilament Surveillance Project (NSP) · The Bluefield Project to Cure Frontotemporal Dementia
Apr 2027Language in Primary Progressive Aphasia · Northwestern University
Aug 2027Single-centre Descriptive Study of Taste in Frontotemporal Lobar Degeneration Through the Analysis of Taste Evoked Potentials · Centre Hospitalier Universitaire Dijon
Sep 2027Repetitive Transcranial Magnetic Stimulation in Frontotemporal Lobar Degeneration · Università degli Studi di Brescia
Nov 2027Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia · Stephanie Grasso

Who these studies take

Of the 8 Frontotemporal Lobar Degeneration studies recruiting now, 7 (88%) set no upper age limit and 1 (13%) stop at 75 or younger. 2 (25%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (50%) take healthy volunteers.

Recruiting studies that take each age, of 8
Age	Women	Men
10	2 (25%)	2 (25%)
18	6 (75%)	6 (75%)
30	6 (75%)	6 (75%)
40	7 (88%)	7 (88%)
50	8 (100%)	8 (100%)
65	8 (100%)	8 (100%)
75	8 (100%)	8 (100%)
85	7 (88%)	7 (88%)

Across all 47 studies, recruiting or not: 2% stop at 75 or younger and 0% at 65; 9% take children; 0% are for women only and 0% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 47 of 47. search them.