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Frontotemporal Dementia clinical trials

The registry lists 208 studies for Frontotemporal Dementia across more than 10 countries. 72 are recruiting or about to start. 71 of them are mainly about Frontotemporal Dementia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Status

Completed
92
Recruiting
51
Active, not recruiting
18
Enrolling by invitation
12
Status unknown
10
Not yet recruiting
9

Phase

Phase 2
36
Phase 1
22
Phase 4
6
Phase 3
6
Early Phase 1
4

Where

United States
103
Canada
34
France
24
Italy
20
United Kingdom
17
Spain
14

Who runs them

Mayo Clinic (7) · University of California, San Francisco (6) · National Institute of Neurological Disorders and Stroke (NINDS) (6) · Assistance Publique - Hôpitaux de Paris (6) · University of Pennsylvania (5) · Chang Gung Memorial Hospital (5) · Massachusetts General Hospital (4) · Johns Hopkins University (4)

What is being tested here

Drugs under test in Frontotemporal Dementia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
AADvac1103
Pittsburgh compound B102
NS101101
Vortioxetine101
Lemborexant101
AV-45101
Oxytocin004
Memantine014
Latozinemab013
Flortaucipir002

Coming up

0phase 3 studies under way
28studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 51 Frontotemporal Dementia studies recruiting now, 29 (57%) set no upper age limit and 5 (10%) stop at 75 or younger. 6 (12%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 30 (59%) take healthy volunteers.

Recruiting studies that take each age, of 51
AgeWomenMen
106 (12%)6 (12%)
1823 (45%)23 (45%)
3030 (59%)30 (59%)
4041 (80%)41 (80%)
5049 (96%)49 (96%)
6550 (98%)50 (98%)
7548 (94%)48 (94%)
8545 (88%)45 (88%)

Across all 208 studies, recruiting or not: 7% stop at 75 or younger and 1% at 65; 12% take children; <1% are for women only and <1% for men only; 46% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Frontotemporal Dementia studies take

Of 19 phase 2 interventional studies under Frontotemporal Dementia, half reached primary completion within 55 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 255 mo42–64 · 19 studies——
Interventional, no phase41 mo21–97 · 54 studies—41 mo21–97 · 51 studies
Observational88 mo44–… · 46 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Stopped1

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 208. Browse all 208 → or search them.