CClinicalTrials.gg
Status unknownNCT01962064COSIMAGEUpdated Oct 14, 2013

Social Cognition in Ageing and in Frontotemporal Lobar Degeneration

An interventional study of Cognitive assessment and Brain imaging examination MRI in Frontotemporal Lobar Degeneration and Aging, sponsored by University Hospital, Caen. Status unknown at 1 site in France. Open to participants aged 40 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-10-14.

Sponsored by University Hospital, Caen · Not applicable, Interventional, and Supportive care

The sponsor has not verified this record recently (last verified Oct 2013), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
80
Allocation
Non-randomized
Ages
40 Years to 80 Years
Sex
All
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Study summary

The purpose of this study is to examine the age and the neurodegenerative disease effects on social cognition. Secondary goals are to better understand the relationships between different component of social cognition, executive functioning, and behavior and describing the neuronal substrates associated to the alteration of the social cognition in ageing and dementia.

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Conditions studied

  • Frontotemporal Lobar Degeneration
  • Aging
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In context

Frontotemporal Lobar Degeneration

40 studies on the registry are indexed under Frontotemporal Lobar Degeneration; 11 are open to participants now.

This study's planned enrollment of 80 is close to the median of 75 across 18 interventional studies indexed under Frontotemporal Lobar Degeneration.

Browse Frontotemporal Lobar Degeneration studies →

Lead sponsor

University Hospital, Caen is the lead sponsor of 505 studies on the registry; 80 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
40 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • All the participants

    • Age between 40 and 80 years
    • Minimum of 7 years of education
    • French native speaker
  • Healthy subjects

    • Non pathological Dementia rating scale score
  • Patients

    • Clinical diagnosis of frontotemporal lobar degeneration

Exclusion criteria

Exclusion Criteria:

  • Chronic neurological disease
  • Encephalitis
  • Endocrinal disease
  • Hepatic disease
  • Case history of head injury with loss of consciousness of more than one hour
  • Case history of stroke
  • Case history of cancer during the five last years except squamous cell carcinomas
  • Alcoholism or drug addiction
  • Major psychiatric disorders according the Diagnostic and Statistical Manual of Mental Disorders
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Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Non-randomized
Intervention model
Factorial assignment
Masking
None (open label)
Enrollment
80 participants (estimated)

Study arms

  • Experimental
    Semantic demantia

    cognitive assessment and Brain imaging examination MRI of patient with the semantic variant of primary progressive aphasia

    Behavioral: Cognitive assessment · Other: Brain imaging examination MRI

  • Experimental
    Frontotemporal dementia

    cognitive assessment and Brain imaging examination MRI of patients with the behavioral variant of frontotemporal lobar degeneration

    Behavioral: Cognitive assessment · Other: Brain imaging examination MRI

  • Experimental
    Elderly

    cognitive assessment and Brain imaging examination MRI of healthy elderly subjects

    Behavioral: Cognitive assessment · Other: Brain imaging examination MRI

  • Experimental
    Young

    cognitive assessment and Brain imaging examination MRI of young subjects

    Behavioral: Cognitive assessment · Other: Brain imaging examination MRI

Interventions

  • BehavioralCognitive assessment
  • OtherBrain imaging examination MRI
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What researchers measure

Primary outcomes

  1. Social cognition scores

    number of correct responses in a social cognition test

    Time frame: 2 years

07

Study locations

1 of 1 sites recruiting
  • Inserm - EPHE - University of Caen U1077
    Caen, 14000, France
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 14, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01962064
Lead sponsor
University Hospital, Caen
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France
Responsible party
Sponsor
First posted
Oct 14, 2013
Start date
Jun 2013
Primary completion
Jul 2014 (estimated)
Completion
Nov 2014 (estimated)
Last update
Oct 14, 2013

Study contacts

Julien Chavant
Contact
memoire-rechcerche.caen@inserm.fr
231065495 ext. +33
Vincent de La Sayette, MD
principal investigator · University Hospital, Caen

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Oct 2013. You cannot join it, but the record below documents what was studied.

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