Esophageal Diseases clinical trials
The registry lists 92 studies for Esophageal Diseases across more than 10 countries. 21 are recruiting or about to start. 33 of them are mainly about Esophageal Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03. Counting its 18 narrower conditions too, such as Esophageal Neoplasms: 5,505 studies, 1,422 open.
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A study of drug A after surgery for early breast cancer
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· Enrollment: 300 → 450 participants
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Who runs them
Asian Institute of Gastroenterology, India (5) · Ellodi Pharmaceuticals, LP (4) · Korea University (4) · Hangzhou Cancer Hospital (3) · CDx Diagnostics (3) · Seoul National University Hospital (2) · Region Örebro County (2) · Changhai Hospital (2)
What is being tested here
Drugs under test in Esophageal Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Camrelizumab | 1 | 0 | 2 |
| Dupilumab | 1 | 1 | 1 |
| Botulinum toxin type A | 1 | 1 | 1 |
| Benmelstobart | 1 | 0 | 1 |
| APT-1011 | 0 | 3 | 4 |
| Cendakimab | 0 | 2 | 2 |
| Paclitaxel | 0 | 0 | 2 |
| Cisplatin | 0 | 0 | 2 |
| Fluorouracil | 0 | 0 | 2 |
| Omeprazole | 0 | 0 | 1 |
Drug classes tested here Immune checkpoint inhibitors 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Nov 2026Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients · Jiangxi Provincial Cancer Hospital
- Dec 2026Esophageal and Gastric Diseases With Robotically Controlled Magnetic Capsule Endoscopy · Bács-Kiskun County Teaching Hospital
- May 2027The French EsoGastricTumours Data Base · University Hospital, Lille
- Jun 2027Comparison of Conventional and Short Submucosal Tunnel Techniques in Type II Achalasia · Asian Institute of Gastroenterology, India
- Jul 2027A Pilot Study Using Gut-Directed Hypnotherapy for Hospitalized Patients · Stanford University
- Nov 2027Implementing Enhanced Recovery After Surgery (ERAS) Protocol in Patients Undergoing Minimal Invasive Esophagectomy · Assiut University
- Nov 2027Clinical Utility of WATS3D: A 5-Year Prospective Study · CDx Diagnostics
Who these studies take
Of the 18 Esophageal Diseases studies recruiting now, 9 (50%) set no upper age limit and 7 (39%) stop at 75 or younger. 3 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (11%) | 2 (11%) |
| 18 | 15 (83%) | 15 (83%) |
| 30 | 15 (83%) | 15 (83%) |
| 40 | 15 (83%) | 15 (83%) |
| 50 | 15 (83%) | 15 (83%) |
| 65 | 15 (83%) | 15 (83%) |
| 75 | 15 (83%) | 15 (83%) |
| 85 | 11 (61%) | 11 (61%) |
Across all 92 studies, recruiting or not: 40% stop at 75 or younger and 13% at 65; 15% take children; 0% are for women only and 2% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 92. Browse all 92 → or search them.
- A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic EsophagitisRecruitingNCT07112378Phase 31 country
- Safety and Feasibility Study of the CELLSPAN Esophageal Implant (CEI) in Patients Requiring Short Segment Esophageal ReplacementRecruitingNCT05877300Phase 11 country
- A Pilot Study Using Gut-Directed Hypnotherapy for Hospitalized PatientsNot yet recruitingNCT07676136Not applicable1 country
- Comparative Assessment of Esophagitis in Cases With and Without Esophageal Motility Disorders: A Prospective StudyRecruitingNCT06835374Not applicable1 country
- The French EsoGastricTumours Data BaseRecruitingNCT025260951 country
- Prospective Multicenter Screening for Thoracic Disease Via RadiographyRecruitingNCT075852141 country
- Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)RecruitingNCT063151791 country
- Esophageal Cancer Risk RegistryRecruitingNCT002605851 country
- PRospective Registry of Esophageal MotilityRecruitingNCT075067461 country
- Clinical Utility of WATS3D: A 5-Year Prospective StudyRecruitingNCT043126331 country
- Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. PyloromyotomyRecruitingNCT06721520Phase 2/31 country
- Comparison of Conventional and Short Submucosal Tunnel Techniques in Type II AchalasiaNot yet recruitingNCT07325071Not applicable
- Esophageal and Gastric Diseases With Robotically Controlled Magnetic Capsule EndoscopyRecruitingNCT040684801 country
- Standard Versus Oesophago-gastric Junction Complex Myotomy for Treatment naïve Type 2 Achalasia PatientsRecruitingNCT06870630Not applicable1 country
- Risk Factors for Sub Mucosal Fibrosis During Achalasia Cardia: A Prospective StudyRecruitingNCT068153411 country
- Role of Topical Steroid Injection With Refractory Benign Esophageal Stricture Endoscopic Dilatation in ChildrenRecruitingNCT06514079Not applicable1 country
- Evaluate the Efficacy of Adding Intraluminal Brachytherapy After CCRT for Local-regional Thoracic Esophageal Cancer.RecruitingNCT06365866Not applicable1 country
- Implementing Enhanced Recovery After Surgery (ERAS) Protocol in Patients Undergoing Minimal Invasive EsophagectomyNot yet recruitingNCT06243887Not applicable
- Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in HumansRecruitingNCT05591053Not applicable1 country
- Camrelizumab Combined With Chemoradiotherapy in Advanced Esophageal Cancer.RecruitingNCT05624099Phase 21 country
- Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma PatientsRecruitingNCT05252078Phase 21 country
- RETHINK REFLUX RegistryActive, not recruitingNCT042533926 countries
- Risk Factors and Biomarkers for Diagnosis and Treatment of EoECompletedNCT019882851 country
- Outcomes After Esophageal Cancer SurgeryCompletedNCT019270161 country
- Safety Study of CC-93538 in Adult and Adolescent Participants With Eosinophilic EsophagitisCompletedNCT04991935Phase 315 countries
- Expanded Access Protocol for Patients With Eosinophilic EsophagitisNo longer availableNCT050951161 country
- 24-Week Induction Study of APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE 3)CompletedNCT05634746Phase 32 countries
- Evaluation of Diagnosis and Treatment Methods in Corrosive Esophagitis: A 26-Year Experience-Based AlgorithmCompletedNCT068167581 country
- Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid TumorsCompletedNCT04774952Phase 11 country
- A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic EsophagitisCompletedNCT04753697Phase 315 countries
- Efficacy of Carbonated Beverages in the Resolution of Alimentary Esophageal ImpactionCompletedNCT06313060Not applicable1 country
- Post Market Clinical Study - Evolution® Esophageal Stent Systems, Europe: Fully and Partially CoveredCompletedNCT051822553 countries
- Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE)Active, not recruitingNCT04149470Phase 41 country
- Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric JunctionCompletedNCT03549494Phase 21 country
- Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 )CompletedNCT03748134Phase 37 countries
- Efficacy and Safety APT-1011 in Adolescent Subjects With Eosinophilic Esophagitis (EoE) - A Sub-Study of the FLUTE-2 TrialCompletedNCT05083312Phase 32 countries
- Mesalazine Oral Suspension in Active Eosinophilic EsophagitisCompletedNCT05488405Phase 21 country
- Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)CompletedNCT04281108Phase 33 countries
- Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE)CompletedNCT03191864Phase 26 countries
- Using Magnetic Field Tracking to Confirm Nasogastric Tube Placement at Point of CareCompletedNCT05204901Not applicable1 country
- The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. RegistryTerminatedNCT029889341 country
- Progenitor Cells in Human EsophagusCompletedNCT031088981 country
- A Study of Anaprazole Sodium Enteric-coated Tablets in the Treatment of Reflux EsophagitisStatus unknownNCT05604261Phase 21 country
- Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid TumorsStatus unknownNCT03634982Phase 11 country
- Detachable String Magnetically Controlled Capsule Endoscopy for Follow-up of Patients With Esophageal DiseasesStatus unknownNCT05469152Not applicable1 country
- EndoVE endosCopic Treatment for Oesophageal and Gastric canceRCompletedNCT04649372Not applicable1 country
- The Strategy of Implementation of the ERAS Protocol After Esophageal SurgeryStatus unknownNCT05311787Not applicable1 country
- Normal Values for Esophageal and Pyloric Impedance Planimetry Under General Anesthesia (NormaFLIP)Status unknownNCT02905669Not applicable1 country
- Twenty Four Hour Ambulatory pH & Impedance Testing: Normative Data for Indian PopulationStatus unknownNCT050041551 country
- Endomina DiverticulumTerminatedNCT03609073Not applicable1 country