Esophagitis, Peptic clinical trials
The registry lists 83 studies for Esophagitis, Peptic across more than 10 countries. 16 are recruiting or about to start. 53 of them are mainly about Esophagitis, Peptic (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-23.
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Who runs them
AstraZeneca (12) · Takeda (10) · Trio Medicines Ltd. (4) · National Taiwan University Hospital (3) · Jiangsu Sinorda Biomedicine Co., Ltd (3) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (2) · Seoul National University Bundang Hospital (2) · Eisai Co., Ltd. (2)
What is being tested here
Drugs under test in Esophagitis, Peptic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Esomeprazole | 1 | 3 | 6 |
| Dexlansoprazole | 0 | 5 | 6 |
| YF 476 | 0 | 0 | 4 |
| D961H | 0 | 2 | 3 |
| Linaprazan glurate | 0 | 1 | 3 |
| Rabeprazole | 0 | 1 | 3 |
| Omeprazole | 0 | 0 | 3 |
| Lansoprazole | 0 | 0 | 2 |
| Fexuprazan | 0 | 1 | 1 |
| Chlorhexidine gluconate | 0 | 0 | 1 |
Drug classes tested here Proton pump inhibitors (PPIs) 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026Feasibility and Safety of Robotic Assisted Proximal Gastrectomy With Double-flap Technique for Proximal Early Gastric Cancer · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Jun 2027Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract Reconstruction · The First Affiliated Hospital with Nanjing Medical University
Who these studies take
Of the 7 Esophagitis, Peptic studies recruiting now, 3 (43%) set no upper age limit and 3 (43%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (71%) | 5 (71%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 3 (43%) | 3 (43%) |
Across all 83 studies, recruiting or not: 42% stop at 75 or younger and 17% at 65; 14% take children; 0% are for women only and 5% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- SPADE Clinical Trial.Oct 23, 2026NCT07892183
Studies
Recruiting first, then most recently updated. Showing 50 of 83. Browse all 83 → or search them.
- SPADE Clinical Trial.RecruitingNCT07892183Not applicable1 country
- PPI Dosing Per CYP2C19 GenotypeNot yet recruitingNCT07843264Phase 4
- Preoperative Predictors of Symptom Improvement After Laparoscopic FundoplicationRecruitingNCT078096201 country
- Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract ReconstructionNot yet recruitingNCT078008192 countries
- A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude (Zaduo County)RecruitingNCT077553841 country
- Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve GastrectomyNot yet recruitingNCT07607067
- Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERDNot yet recruitingNCT07178821Not applicable1 country
- A Clinical Trial of Anaprazole for Treating Reflux Esophagitis.RecruitingNCT07010107Phase 31 country
- Feasibility and Safety of Robotic Assisted Proximal Gastrectomy With Double-flap Technique for Proximal Early Gastric CancerRecruitingNCT05892289Not applicable1 country
- A Phase III Clinical Trial for Efficacy and Safety Evaluation of JP-1366 Tablets on Reflux EsophagitisRecruitingNCT06850480Phase 31 country
- Preliminary Efficacy Analysis of "C" Single Flap Plasty Reconstruction After Laparoscopic Proximal GastrectomyNot yet recruitingNCT06741501Not applicable1 country
- Preliminary Efficacy Analysis of 'λ+α' Double-Tract Reconstruction After Laparoscopic Proximal GastrectomyRecruitingNCT06475170Not applicable1 country
- Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract After Proximal GastrectomyNot yet recruitingNCT06062225Not applicable
- Jinghua Weikang Capsule in the Treatment of Reflux EsophagitisNot yet recruitingNCT06056973Phase 4
- Laparoscopic Proximal Gastrectomy With Double-flap Technique Versus Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction for Proximal Early Gastric CancerNot yet recruitingNCT05890339Not applicable1 country
- Clinical Trial of Reconstruction After Proximal GastrectomyNot yet recruitingNCT05418920Not applicable
- FundoRing Roux-en-Y Gastric Bypass Versus FundoRing One Anastomosis Gastric BypassCompletedNCT07486765Not applicable1 country
- A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal UlcerCompletedNCT03553563Phase 31 country
- Mass Balance Study of [14C]X842 in Healthy Adult Male SubjectsCompletedNCT07107672Phase 11 country
- The Phase III Clinical Trial of X842 Capsules for Reflux EsophagitisCompletedNCT07079540Phase 31 country
- Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux EsophagitisCompletedNCT04531475Phase 21 country
- Special Drug Use Surveillance of Vonoprazan for "Maintenance Therapy of Reflux Esophagitis: Long-term Use"CompletedNCT032140811 country
- Role of ARMA in Selective Subset of Refractory GERD Patients.CompletedNCT05899491Not applicable1 country
- Treatment of Reflux With Sleeve GastrectomyActive, not recruitingNCT06170060Not applicable1 country
- A Study on Vonoprazan in the Real-world Clinical Practice in ChinaCompletedNCT045016271 country
- Quality of Life in New Treatable Therapy as Rabeprazole Option for Refractory Reflux EsophagitisCompletedNCT013215671 country
- The Efficacy and Safety of DWP14012 in Chinese Patients With Reflux EsophagitisCompletedNCT05813561Phase 31 country
- Trimebutine Maleate Combined With Rabeprazole in Patients With Grade A or B Reflux Esophagitis Whose Symptoms Refractory to RabeprazoleWithdrawnNCT02986685Phase 41 country
- A Study of Anaprazole Sodium Enteric-coated Tablets in the Treatment of Reflux EsophagitisStatus unknownNCT05604261Phase 21 country
- Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal MicrobiomeCompletedNCT02513784Not applicable1 country
- A Novel Endoloop Pre-test to Treat Gastroesophageal RefluxStatus unknownNCT05192538Not applicable1 country
- Study of Dietary Patterns and Food Diversity in Russian GERD PatientsStatus unknownNCT04252144Not applicable1 country
- Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's OesophagusCompletedNCT03388047Not applicable1 country
- Preliminary Efficacy Analysis of Cheng's Giraffe Reconstruction After Proximal GastrectomyStatus unknownNCT04657848Not applicable1 country
- The Role of HIF-2a in the Pathogenesis of Reflux EsophagitisCompletedNCT01733810Not applicable1 country
- Evaluate the Intestinal Microbiome in Patients With Erosive Gastroesophageal Reflux Disease and in Asymptomatic Healthy ControlsCompletedNCT042482961 country
- Drug Use Surveillance of Vonoprazan for "Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis"CompletedNCT032149521 country
- Efficacy of DA-5204 on Gastroesophageal Reflux DiseaseCompletedNCT03998969Phase 31 country
- Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory EvaluationCompletedNCT03116841Phase 41 country
- Double Tract Anastomosis and Gastric Tube Anastomosis to Proximal GastrectomyTerminatedNCT02288728Not applicable1 country
- To Evaluate Efficacy and Safety of Z-215 in Erosive EsophagitisCompletedNCT02463643Phase 21 country
- Nexium Capsules S-CEI for Justification of Esomeprazole in Acid Related Disease for Reflux Symptom Healing Based on Patient Clinical OutcomesCompletedNCT024774751 country
- A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related DiseasesCompletedNCT02153398Phase 31 country
- Laparoscopy-assisted Proximal Gastrectomy Versus and Laparoscopy-assisted Total GastrectomyTerminatedNCT01433861Phase 31 country
- Quantifying Effects of Treatment of Pediatric DysphoniaTerminatedNCT00237679Not applicable1 country
- The Study to Evaluate Efficacy and Safety of Newrabell® Tab.(Rabeprazole Sodium) 10mg b.i.d in Refractory GERDCompletedNCT01860482Phase 41 country
- Compare D961H 20 mg Bid and 20 mg qd in Patients With Refractory Reflux Esophagitis (Inflammation of Lower Esophagus)CompletedNCT01669811Phase 31 country
- Nexium Capsules RE Maintenance Specific Clinical Experience InvestigationCompletedNCT015626391 country
- Study to Investigate the Safety, Tolerability and Efficacy of YH4808 in Patients With Reflux EsophagitisCompletedNCT01538849Phase 21 country
- Nexium Capsules Clinical Experience InvestigationCompletedNCT014344851 country