Esophageal and Gastric Varices clinical trials
The registry lists 150 studies for Esophageal and Gastric Varices across more than 10 countries. 39 are recruiting or about to start. 110 of them are mainly about Esophageal and Gastric Varices (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
Shanghai Zhongshan Hospital (13) · West China Hospital (9) · Assiut University (8) · Tanta University (7) · Taipei Veterans General Hospital, Taiwan (6) · Qilu Hospital of Shandong University (6) · Second Affiliated Hospital, School of Medicine, Zhejiang University (4) · Instituto Ecuatoriano de Enfermedades Digestivas (3)
What is being tested here
Drugs under test in Esophageal and Gastric Varices studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Carvedilol | 1 | 2 | 10 |
| Terlipressin | 1 | 0 | 3 |
| Pantoprazole | 1 | 0 | 2 |
| Sucralfate | 1 | 0 | 1 |
| Apixaban | 1 | 0 | 1 |
| Vonoprazan | 1 | 0 | 1 |
| Ertapenem | 1 | 0 | 1 |
| Propranolol | 0 | 2 | 6 |
| Polidocanol | 0 | 0 | 4 |
| Enbucrilate | 0 | 0 | 3 |
Drug classes tested here Beta blockers 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils · Medtronic Endovascular
- Dec 2026Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial. · King's College Hospital NHS Trust
- Dec 2026Optimizing Endoscopic and Interventional Treatment for Portal Hypertensive Bleeding · Shanghai Zhongshan Hospital
- Dec 2026Prophylactic Endoscopic Variceal Ligation in Patients With High-risk Esophageal Varices Receiving Atezo/Bev for HCC · Asan Medical Center
- Apr 2027Ultrasound Prediction of Esophageal Variceal Bleeding Risk · Assiut University
- Apr 2027Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis · Asian Institute Of Medical Sciences
- Jun 2027A Prospective, Multicenter, Randomized Controlled Trial Investigating the Impact of Fasting Duration on Postoperative Rebleeding Following Esophageal Variceal Ligation. · The First Affiliated Hospital of Zhengzhou University
- Aug 20272D-shear Wave Spleen Elastography in Clinically Significant Portal Hypertension and High-risk Varices · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Sep 2027Baveno VIII Criteria for Portal Hypertension in Egyptian Patients · Assiut University
- Nov 2027Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram Trial · University of California, Los Angeles
Who these studies take
Of the 20 Esophageal and Gastric Varices studies recruiting now, 13 (65%) set no upper age limit and 1 (5%) stop at 75 or younger. 1 (5%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (5%) | 1 (5%) |
| 18 | 17 (85%) | 17 (85%) |
| 30 | 20 (100%) | 20 (100%) |
| 40 | 20 (100%) | 20 (100%) |
| 50 | 20 (100%) | 20 (100%) |
| 65 | 20 (100%) | 20 (100%) |
| 75 | 20 (100%) | 20 (100%) |
| 85 | 16 (80%) | 16 (80%) |
Across all 150 studies, recruiting or not: 32% stop at 75 or younger and 5% at 65; 10% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Esophageal and Gastric Varices studies take
Of 28 interventional studies with no phase under Esophageal and Gastric Varices, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 24 mo19–… · 28 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting1
- Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram TrialNov 12, 2026NCT07168395
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 150. Browse all 150 → or search them.
- Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram TrialRecruitingNCT07168395Not applicable1 country
- The Value of Spleen Thickness and Spleen Diameter for Gastroesophageal Varices Diagnosis in Compensated CirrhosisRecruitingNCT079207441 country
- Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable CoilsEnrolling by invitationNCT076398531 country
- Baveno VIII Criteria for Portal Hypertension in Egyptian PatientsNot yet recruitingNCT07842666
- A Prospective, Multicenter, Randomized Controlled Trial Investigating the Impact of Fasting Duration on Postoperative Rebleeding Following Esophageal Variceal Ligation.RecruitingNCT07774143Not applicable1 country
- Clinical Trial to Evaluate the Effectiveness of Liver Shear Wave Quantization Detector Spleen Stiffness Value in the Diagnosis of Esophageal VaricesNot yet recruitingNCT07753577
- Cyanoacrylate Glue Versus Absorbable Gelatin Sponge for Gastric VaricesNot yet recruitingNCT07699354Not applicable1 country
- Topical Application of Sucralfate in Promoting Healing of Esophageal Ulcers After Esophageal Varices LigationNot yet recruitingNCT07679191Not applicable
- Underdilated VCX-TIPS Versus EVL Plus NSBB for Secondary Prophylaxis of Variceal Bleeding in CirrhosisNot yet recruitingNCT07587671Not applicable1 country
- Ultrasound Prediction of Esophageal Variceal Bleeding RiskNot yet recruitingNCT07571876
- The Diagnostic Value of Subharmonic Imaging Technology Combined With Liver Stiffness and Platelet Count for High-risk Esophageal and Gastric Varices in Patients With Liver CirrhosisRecruitingNCT07151885Not applicable1 country
- Apixaban-PK Trial: Preventing Portal Hypertension Complications in CirrhosisRecruitingNCT07521332Phase 41 country
- Pantoprazole After Prophylactic Endoscopic Variceal TreatmentEnrolling by invitationNCT07248722Not applicable1 country
- Optimizing Endoscopic and Interventional Treatment for Portal Hypertensive BleedingNot yet recruitingNCT07502729
- Non-invasive Predictors of Esophageal Varices and Their Correlation to Upper Endoscopic FindingsNot yet recruitingNCT07464522
- Evaluating the Efficacy of Vonoprazan in Preventing Post-Endoscopic Variceal Band Ligation Ulcers: A Randomized Controlled TrialRecruitingNCT07267260Phase 21 country
- 2D-shear Wave Spleen Elastography in Clinically Significant Portal Hypertension and High-risk VaricesRecruitingNCT071226221 country
- TIPS for Complicated Portal Hypertension Related to Porto-Sinusoidal Vascular DiseaseRecruitingNCT071636891 country
- Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological FactorsRecruitingNCT065496735 countries
- Prophylactic Endoscopic Variceal Ligation in Patients With High-risk Esophageal Varices Receiving Atezo/Bev for HCCRecruitingNCT06819566Phase 21 country
- Efficacy and Safety of Contrast EUS-Guided Tissue Glue/Coil Devascularization vs. BRTO for Preventing Recurrent Gastric Variceal BleedingNot yet recruitingNCT07049146Not applicable1 country
- Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal HypertensionRecruitingNCT069705091 country
- Esophageal Varices Prophylaxis in Hepatocellular Carcinoma Treated With Atezolizumab and BevacizumabRecruitingNCT06961526Not applicable1 country
- Fecal Calprotectin for Prediction of Esophageal Varices in Cirrhotic PatientsRecruitingNCT069087981 country
- Cross-section Band Ligation Versus Stepladder Band Ligation of Esophageal VaricesRecruitingNCT06881082Not applicable1 country
- Evaluation of Endoscopic Treatment Effect Based on HVPGEnrolling by invitationNCT068635191 country
- Endoscopic Variceal Ligation vs Carvedilol for the Prevention of First Esophageal Variceal Bleeding in Patients With HCCRecruitingNCT06594744Phase 41 country
- Carvedilol Plus EVL or Not for the Primary Prevention of Esophageal Variceal Bleeding in Carvedilol Non-respondersRecruitingNCT06594783Phase 41 country
- Liver and Spleen Stiffness to Predict the Presence of Esaphageal Varices in Cirrhotic with Advanced HCCEnrolling by invitationNCT067732601 country
- Role of MDCT in Grading of Esophageal VaricesNot yet recruitingNCT06707298
- Detachable Clip-assisted Endoscopic Cyanoacrylate Injection in the Treatment of Gastric VaricesRecruitingNCT06670157Not applicable1 country
- EUS Guided Coil Embolization for Primary Prophylaxis of Gastric VaricesRecruitingNCT06370169Not applicable1 country
- Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver CirrhosisNot yet recruitingNCT03130127Not applicable
- Upper Endoscopy in Cirrhotic Patients With Upper Gastrointestinal BleedingNot yet recruitingNCT06214234Not applicable1 country
- Ulcer Bleeding After Band Ligation of Esophageal VaricesNot yet recruitingNCT06082219
- Spleen Stiffness as a Measure to Assess the REsponse to β Blocker Therapy (SPARE-B)Not yet recruitingNCT060508371 country
- Clinical Study on Endoscopic Management of GOV1 Esophagogastric VaricesNot yet recruitingNCT05978752Not applicable
- Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal BleedingRecruitingNCT04499898Phase 2/31 country
- Antibiotic Prophylaxis in Patients Undergoing GVORecruitingNCT04140578Phase 41 country
- Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH CirrhosisTerminatedNCT04365868Phase 2/315 countries
- Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.Active, not recruitingNCT05872698Phase 41 country
- Study on Portal Vein Pressure Gradient Measurement Under Endoscopic Ultrasound Guidance for Gastric Fundal VaricesCompletedNCT074787701 country
- Wired Magnetically Assisted Capsule Endoscopy and Esophageal VaricesCompletedNCT06017102Not applicable1 country
- Clip and Coil in Fundal Gastric Varices With a Large ShuntCompletedNCT072635031 country
- Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal VaricesTerminatedNCT03624517Phase 41 country
- A Digital Tongue Diagnosis Model for High- and Low-risk Esophagogastroduodenal Varices in CirrhosisActive, not recruitingNCT059799351 country
- Efficacy and Safety of Intravenous Vitamin K1 in Management of Acute Variceal BleedingCompletedNCT06839352Phase 41 country
- Replicor Compassionate Access ProgramNo longer availableNCT056835485 countries
- TIPS Plus Transvenous Obliteration for Gastric VaricesCompletedNCT040442481 country
- Impact of EUS Guided Treatment of Gastric VaricesCompletedNCT055216851 country