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CompletedNCT06816758Updated May 21, 2025

Evaluation of Diagnosis and Treatment Methods in Corrosive Esophagitis: A 26-Year Experience-Based Algorithm

An observational study in Esophageal Diseases, sponsored by Caner İşevi, MD. Completed at 1 site in Turkey. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-05-21.

Sponsored by Caner İşevi, MD · Observational

Study type
Observational
Model
Other
Time perspective
Retrospective
Enrollment
501
Ages
18 Years and older
Sex
All
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Study summary

This study aims to evaluate the diagnosis and treatment methods for corrosive esophagitis based on 26 years of clinical experience. It will retrospectively analyze patient records to identify patterns in clinical outcomes, complications, and the effectiveness of treatment strategies. The study focuses on optimizing patient care by proposing a diagnosis and treatment algorithm that can guide future clinical practices. Data will be collected from hospital archives and electronic health records, covering cases of corrosive esophagitis managed at Ondokuz Mayıs University between 1998 and 2024.

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Conditions studied

  • Esophageal Diseases

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03

In context

Esophageal Diseases

92 studies on the registry are indexed under Esophageal Diseases; 21 are open to participants now.

This study's enrollment of 501 is close to the median of 501 across 24 observational studies indexed under Esophageal Diseases.

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Lead sponsor

Caner İşevi, MD is the lead sponsor of 7 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

This study focuses on patients diagnosed with corrosive esophagitis due to the ingestion of corrosive substances. The population includes individuals aged over 18 years who were hospitalized and treated at Ondokuz Mayıs University Thoracic Surgery Department between 1998 and 2024. The patients underwent clinical, laboratory, and radiological evaluations, and their outcomes were assessed retrospectively.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients diagnosed with corrosive esophagitis due to corrosive substance ingestion.
  • Hospitalized and treated at Ondokuz Mayıs University Thoracic Surgery Department.
  • Patients who underwent clinical, laboratory, and radiological evaluations to confirm the diagnosis.
  • Patients who were monitored and met follow-up criteria during their treatment.
  • Patients above 18 years of age

Exclusion criteria

Exclusion Criteria:

  • Patients under 18 years of age.
  • Patients who refused hospitalization or treatment.
  • Patients who ingested non-corrosive or non-toxic substances (verified by the Ministry of Health Poison Information Center).
  • Patients lost to follow-up or did not complete follow-up requirements.
  • Patients with incomplete data during the diagnostic or treatment process.
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Study design

Observational model
Other
Time perspective
Retrospective
Enrollment
501 participants (actual)
Patient registry
No

Interventions

  • OtherRoutine Care for Corrosive Esophagitis

    This is an observational study, so participants are not assigned interventions. However, the study investigates the outcomes of patients diagnosed with corrosive esophagitis who received routine clinical care. The exposure of interest includes diagnostic and treatment procedures such as endoscopic evaluation (Zargar classification), proton pump inhibitors, corticosteroid therapy, and surgical interventions for complications like strictures. The outcomes and clinical data collected reflect routine care practices over 26 years.

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What researchers measure

Primary outcomes

  1. Incidence of Esophageal Stricture, Perforation, and Other Related Complications

    The number of patients who develop esophageal strictures, perforation, or other complications within 1 month post-admission will be recorded.

    Time frame: Within 1 month after hospital admission

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Study locations

1 site
  • Ondokuz Mayıs University Faculty of Medicine
    Samsun, Turkey
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References and documents

Individual participant data

Plan to share: Yes

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 21, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06816758
Lead sponsor
Caner İşevi, MD
Responsible party
Caner İşevi, MD (Principal Investigator, Ondokuz Mayıs University) — Sponsor-investigator
First posted
Feb 10, 2025
Start date
May 1, 2025
Primary completion
May 10, 2025
Completion
May 15, 2025
Last update
May 21, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

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