Dupuytren Contracture clinical trials
The registry lists 78 studies for Dupuytren Contracture across more than 10 countries. 18 are recruiting or about to start. 69 of them are mainly about Dupuytren Contracture (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Endo Pharmaceuticals (10) · Universitaire Ziekenhuizen KU Leuven (6) · Indiana Hand to Shoulder Center (2) · State University of New York (2) · University of Texas at Austin (2) · University of Oxford (2) · Sunnybrook Health Sciences Centre (2) · Cairo University (2)
What is being tested here
Drugs under test in Dupuytren Contracture studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring · Mayo Clinic
- Jan 2027Skin Involvement in Dupuytren Surgical Treatment Outcome · Universitaire Ziekenhuizen KU Leuven
- Jan 2027NAC-REPAIR for Post-surgical Pain · University of Arizona
- Jan 2027Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test · University of Texas at Austin
- Mar 2027Nodular Shrinking in Dupuytren Disease · Universitaire Ziekenhuizen KU Leuven
- Mar 2027Micronerves in Dupuytren and the Impact of Its Dissection on Recurrence · Universitaire Ziekenhuizen KU Leuven
- Mar 2027Effectiveness of Percutaneous Needle Aponeurotomy · Assistance Publique - Hôpitaux de Paris
- Mar 2027Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease · Elsan
- Apr 2027Ultrasound Features of Dupuytren's Disease · Universitaire Ziekenhuizen KU Leuven
- Jul 2027Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's Contracture · CONNEXT
Who these studies take
Of the 12 Dupuytren Contracture studies recruiting now, 10 (83%) set no upper age limit and 1 (8%) stop at 75 or younger. 1 (8%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (8%) | 1 (8%) |
| 18 | 10 (83%) | 10 (83%) |
| 30 | 10 (83%) | 10 (83%) |
| 40 | 10 (83%) | 10 (83%) |
| 50 | 12 (100%) | 12 (100%) |
| 65 | 12 (100%) | 12 (100%) |
| 75 | 12 (100%) | 12 (100%) |
| 85 | 11 (92%) | 11 (92%) |
Across all 78 studies, recruiting or not: 8% stop at 75 or younger and 0% at 65; 5% take children; 0% are for women only and 0% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
- Kinesitherapy Plus Osteopathy After Surgery for Dupuytren DiseaseOct 30, 2026NCT07907146
Studies
Recruiting first, then most recently updated. Showing 50 of 78. Browse all 78 → or search them.
- Kinesitherapy Plus Osteopathy After Surgery for Dupuytren DiseaseNot yet recruitingNCT07907146Not applicable1 country
- DEPART Study at YaleNot yet recruitingNCT07661342Phase 31 country
- Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal TestNot yet recruitingNCT07158892Not applicable1 country
- Radiation Therapy for Dupuytren's Contracture Following Non-Surgical ReleaseRecruitingNCT06330545Not applicable1 country
- NAC-REPAIR for Post-surgical PainNot yet recruitingNCT07227649Phase 21 country
- Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's ContractureRecruitingNCT07640425Phase 1/21 country
- Nodular Shrinking in Dupuytren DiseaseRecruitingNCT06321991Phase 21 country
- Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's DiseaseRecruitingNCT05067764Not applicable1 country
- Post-contracture Release Radiation for Dupuytren's DiseaseRecruitingNCT041223131 country
- Micronerves in Dupuytren and the Impact of Its Dissection on RecurrenceRecruitingNCT061429291 country
- The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and ScarringRecruitingNCT03155854Not applicable1 country
- Ultrasound Features of Dupuytren's DiseaseRecruitingNCT06956027Not applicable1 country
- Effect of Transfer Energy Capacitive and Resistive Therapy on Palmar FibromatosisNot yet recruitingNCT07443371Not applicable1 country
- Prognostic Profile of Dupuytren's Disease: a Cohort Study (PRODUCT)Not yet recruitingNCT07353060Not applicable1 country
- Effectiveness of Percutaneous Needle AponeurotomyRecruitingNCT03797690Not applicable1 country
- Evaluating Ultrasound-Guided Needle Knife for Dupuytren's ContractureRecruitingNCT06788847Not applicable1 country
- Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's ContractureRecruitingNCT05300893Not applicable1 country
- Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's ContractureRecruitingNCT05440240Phase 41 country
- Effect Of Extracorporeal Shock Wave Therapy On Ultrasonography Changes In Patients With Palmar Fibromatosis: A Randomized Controlled TrialCompletedNCT06248866Not applicable1 country
- Skin Involvement in Dupuytren Surgical Treatment OutcomeActive, not recruitingNCT07470684Not applicable1 country
- Trial Comparing Treatment Strategies in Dupuytren's ContractureActive, not recruitingNCT03192020Phase 41 country
- MiniFlo for Advanced Dupuytren's DiseaseCompletedNCT07505563Not applicable1 country
- Palmaris Longus Muscle and DupuytrenCompletedNCT06281509Not applicable1 country
- Nylon Versus Chromic Gut Sutures for Minor Hand SurgeryCompletedNCT03407820Not applicable1 country
- Goniometry and Goniometric Measurement on Standardised Images in Dupuytren's DiseaseCompletedNCT062636991 country
- Effectiveness of Splinting After Collagenase InjectionCompletedNCT04874870Phase 31 country
- The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist SurgeryActive, not recruitingNCT06806410Phase 41 country
- Repurposing Anti-TNF for Treating Dupuytren's DiseaseCompletedNCT03180957Phase 22 countries
- Real-World Data Study to Understand Participant Treatment Outcomes for Dupuytren's ContractureTerminatedNCT058770661 country
- Natural Disease Progress of Dupuytren DiseaseCompletedNCT019231031 country
- Treatment of Dupuytren's Disease With Minimal Invasive Surgery and VIVOSORB® Resorbable Implant DeviceActive, not recruitingNCT03741764Not applicable1 country
- Hand Therapy or Not Following Collagenase Treatment for Dupuytren's Contracture?CompletedNCT03580213Not applicable1 country
- Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren'sCompletedNCT02725528Phase 31 country
- Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNFCompletedNCT02647619Phase 41 country
- Is wGRS Associated With DD Recurrence?CompletedNCT029831621 country
- Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers.CompletedNCT04669704Not applicable1 country
- BOND Study: the Benefit Of Night Splinting in Dupuytrens'WithdrawnNCT03031080Not applicable1 country
- The Role of Tranexamic Acid in Reducing Post Operative Hand Edema After Hand and Wrist SurgeryStatus unknownNCT04907812Phase 41 country
- Percutaneous Aponeurotomy in the Treatment of Dupuytren's DiseaseCompletedNCT02474576Not applicable1 country
- Ultrasound B Mode Imaging and ElastographyCompletedNCT046071871 country
- Liposome Bupivacaine for WRIST BlocksCompletedNCT03106519Phase 21 country
- Collagenase is a Common Treatment of MCP and PIP Joint Contractures in Dupuytrens DiseaseCompletedNCT03331926
- Tolerance and Efficacy Study of Second-line Surgery After Percutaneous Needle Aponeurotomy for Dupuytren's Disease.Status unknownNCT04164953Not applicable1 country
- Question Prompt List for Common Hand ConditionsCompletedNCT03868449Not applicable1 country
- Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand SurgeryCompletedNCT03111186Phase 21 country
- Comparing the Effectiveness of Two Post-fasciectomy Rehabilitation Protocols in Patients With Dupuytren's DiseaseStatus unknownNCT03982719Not applicable1 country
- Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine DataCompletedNCT03573765
- AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's ContractureCompletedNCT00528606Phase 31 country
- Post Approval Commitment StudyCompletedNCT014447292 countries
- Phase 2a Dose-Ranging Study to Evaluate Safety and Effectiveness of AA4500 in Treatment of Dupuytren's Disease NodulesCompletedNCT02193828Phase 22 countries