Keenova Therapeutics plc: Dupuytren Contracture trials

The registry lists 13 Dupuytren Contracture studies with Keenova Therapeutics plc as lead sponsor. 0 are open to participants now and 9 have results posted.

Phase 1 1Phase 2 1Phase 3 6Phase 4 1No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Phase 2a Dose-Ranging Study to Evaluate Safety and Effectiveness of AA4500 in Treatment of Dupuytren's Disease NodulesCompletedNCT02193828Phase 2Results posted
• Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's ContracturesCompletedNCT01674634Phase 3Results posted
• Retreatment of Recurrent Dupuytren's ContracturesCompletedNCT01498640Phase 4Results posted
• Administration of Two Injections for Multiple Dupuytren's ContracturesCompletedNCT01407068Phase 3Results posted
• Non-US Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's DiseaseCompletedNCT00533273Phase 3Results posted
• A Pharmacokinetic Study of AA4500 (XIAFLEX™, Proposed Name) in Subjects With Dupuytren's ContractureCompletedNCT00528931Phase 1Results posted
• Safety and Efficacy Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's DiseaseCompletedNCT00528840Phase 3Results posted
• AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's ContractureCompletedNCT00528606Phase 3Results posted
• AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's DiseaseCompletedNCT00528424Phase 3Results posted
• Real-World Data Study to Understand Participant Treatment Outcomes for Dupuytren's ContractureTerminatedNCT05877066
• CORRECT: COmmunity RegistRy Study Evaluating Dupuytren's Contracture TreatmentCompletedNCT01715467
• Post Approval Commitment StudyCompletedNCT01444729
• Longterm Observational Study in Subjects Treated With AA4500 in AUX-CC-854, 856, 857, 858 & 859CompletedNCT00954746