Dental Pulp Diseases clinical trials
The registry lists 130 studies for Dental Pulp Diseases across more than 10 countries. 37 are recruiting or about to start. 91 of them are mainly about Dental Pulp Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its 4 narrower conditions too, such as Dental Pulp Necrosis: 708 studies, 184 open.
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Who runs them
Cairo University (14) · Minia University (6) · British University In Egypt (5) · Tanta University (4) · University of Minnesota (3) · TC Erciyes University (3) · Ain Shams University (3) · University of California, Los Angeles (3)
What is being tested here
Drugs under test in Dental Pulp Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ferrosoferric Oxide | 1 | 0 | 2 |
| Lidocaine | 1 | 0 | 2 |
| Ginger extract | 1 | 1 | 1 |
| Diclofenac | 1 | 1 | 1 |
| Articaine hydrochloride | 1 | 0 | 1 |
| Calcium Hydroxide | 0 | 0 | 2 |
| Tetracaine | 0 | 0 | 2 |
| Oxymetazoline | 0 | 0 | 2 |
| Saline Solution | 0 | 0 | 1 |
| Sodium Chloride | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Dec 2026Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary Molars · Cairo University
- Mar 2027Exploration of the Utility of Dental-dedicated MRI for Dentistry · University of Minnesota
- May 2027Endo-perio Disease - Treatment Outcomes Using Conventional and Hydraulic Calcium Silicate Sealer With or Without LPRF · King's College London
- May 2027Photobiomodulation After Nonsurgical Root Canal Treatment · University of Minnesota
Who these studies take
Of the 16 Dental Pulp Diseases studies recruiting now, 5 (31%) set no upper age limit and 10 (63%) stop at 75 or younger. 5 (31%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 12 (75%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (6%) | 1 (6%) |
| 18 | 10 (63%) | 10 (63%) |
| 30 | 13 (81%) | 13 (81%) |
| 40 | 13 (81%) | 13 (81%) |
| 50 | 11 (69%) | 11 (69%) |
| 65 | 8 (50%) | 8 (50%) |
| 75 | 8 (50%) | 8 (50%) |
| 85 | 6 (38%) | 6 (38%) |
Across all 130 studies, recruiting or not: 72% stop at 75 or younger and 65% at 65; 49% take children; 0% are for women only and 2% for men only; 65% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Dental Pulp Diseases studies take
Of 60 interventional studies with no phase under Dental Pulp Diseases, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 18 mo9–34 · 60 studies | — | 18 mo9–34 · 60 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
Newly registered1
- Photobiomodulation After Nonsurgical Root Canal TreatmentOct 21, 2026NCT07886723
Studies
Recruiting first, then most recently updated. Showing 50 of 130. Browse all 130 → or search them.
- Photobiomodulation After Nonsurgical Root Canal TreatmentNot yet recruitingNCT07886723Not applicable1 country
- Nanozymes in EndodonticsEnrolling by invitationNCT07518901Phase 41 country
- Clinical Outcomes of Root Canal Treatment Using Modern Irrigation ProtocolsNot yet recruitingNCT07852312Not applicable1 country
- Exploration of the Utility of Dental-dedicated MRI for DentistryRecruitingNCT069481621 country
- Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic MicrosurgeryRecruitingNCT06574152Not applicable1 country
- Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary MolarsNot yet recruitingNCT07675330Not applicable1 country
- Chloramphenicol, Tetracycline, Zinc Oxide and Eugenol Paste (CTZ Paste) for Emergency Dental Treatment in Public Health Settings: A Randomized TrialNot yet recruitingNCT07542639Early Phase 1
- Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic BiomarkerRecruitingNCT07452614Not applicable1 country
- Evaluation of Three Pulp Vitality TestsNot yet recruitingNCT026365041 country
- Optimizing Pulp Management in Autotransplantation of Mature Third Molars: A Randomized Controlled TrialNot yet recruitingNCT07291531Not applicable1 country
- Comparison of Hyaluronic Acid, TheraCal, and Mineral Trioxide Aggregate as Pulpotomy Agents in Primary MolarsNot yet recruitingNCT07168811Not applicable1 country
- Comparison of Post Cementation Sensitivity Between RMGIC and GIC as Luting Materials in a Randomized Clinical TrialEnrolling by invitationNCT07102121Not applicable1 country
- The Antimicrobial Potential of Diclofenac Sodium as an Intracanal MedicamentRecruitingNCT06207253Phase 2/31 country
- Comparison of 3Mixtatin Pulpotomy and Metapex Pulpectomy in Primary Molars With Irreversible PulpitisNot yet recruitingNCT06925490Phase 1
- Postoperative Pain and Incidence of Extrusion Following the Use of Two Intra-canal Medications in Retreatment of Single Rooted TeethNot yet recruitingNCT06913673Phase 2
- Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary MolarsNot yet recruitingNCT06871709Not applicable1 country
- The Effect of Different Risk Factors on the Success Rate of VPTRecruitingNCT068444481 country
- Zinc Oxide Ozonated Olive Oil in LSTRRecruitingNCT06854744Not applicable1 country
- Effect of Cavity Disinfectants on Post Operative Pain & Success of Partial Caries RemovalRecruitingNCT06836882Not applicable1 country
- Role of GTR on Healing Outcome & Quality of Life in Combined Endo Perio Lesions With CommunicationRecruitingNCT06643663Not applicable1 country
- Caries Location and Its Effect on the Success Rate of Indirect Pulp Treatment in Primary MolarsNot yet recruitingNCT06675058Not applicable
- Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary MolarsNot yet recruitingNCT06611631Phase 11 country
- Irrigation Activating Techniques on Irrigant Penetration Depth and Microbial ReductionRecruitingNCT06660797Not applicable1 country
- Treatment Outcome of Ortho MTA (BioMTA®) Cement vs AH Plus® Bioceramic Sealer (Dentsply).RecruitingNCT05984940Not applicable1 country
- Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal MedicationRecruitingNCT06196515Phase 2/31 country
- Evaluation of Success Rate of Partial Pulpotomy Versus Complete Pulpotomy in Primary Molars Using NeoPUTTY MTANot yet recruitingNCT06524076Not applicable
- Antimicrobial Efficacy of Nano-Based ICM on E.FRecruitingNCT06533215Not applicable1 country
- 3Mixtatin and MTA Vital Pulpotomy in Primary MolarsNot yet recruitingNCT06478940Phase 1
- the Efficacy of Ginger Powder as an Analgesic for Intraoperative and Post- Endodontic Pain ManagementNot yet recruitingNCT06439212Phase 3
- Effect of Different Irrigation Solutions on Postoperative Pain and Lesion HealingRecruitingNCT06386991Phase 41 country
- Outcomes of NeoMTA and NeoPUTTY Pulpotomies in Primary MolarsNot yet recruitingNCT06380296Not applicable
- Sodiumhexametaphosphate Versus MTA as Pulp Capping Material for Immature Permanent TeethNot yet recruitingNCT06170762Not applicable
- Evaluation of Different Materials in Pulpotomy of Primary MolarsNot yet recruitingNCT05981352Not applicable
- Articaine Efficiency in Pulpectomy of Children With Irreversible Pulpitis Under the Age of FourRecruitingNCT05944341Not applicable1 country
- Endo-perio Disease - Treatment Outcomes Using Conventional and Hydraulic Calcium Silicate Sealer With or Without LPRFNot yet recruitingNCT05681754Not applicable1 country
- Outcome of Endodontic Treatment and Retreatment With a Bioceramic SealerRecruitingNCT04528979Not applicable1 country
- Outcome of Endodontic Retreatment in One or Two VisitsRecruitingNCT04527705Not applicable1 country
- Microbial Load After Apical Enlargement in Asymptomatic Teeth With Periapical LesionCompletedNCT060351851 country
- In-Vivo Diagnostic Accuracy and Repeatability of Root ZX3 for Working-Length Determination in Single-Rooted Teeth: Agreement With CBCT and Microscopic ValidationCompletedNCT07689838Not applicable1 country
- Knowledge of Vital Pulp Therapy in Permanent Teeth After Educational Programme: A Before and After StudyCompletedNCT064678901 country
- Postoperative Pain After OCT or EDTA Irrigation in Regenerative Endodontic TreatmentCompletedNCT07722416Not applicable1 country
- Comparative Evaluation of Three Different Pulpotomy Agents in Primary MolarsCompletedNCT07541976Phase 21 country
- A Randomized Controlled Trial Evaluating Whether Pre-operative Trinase Reduces Post-operative Pain in Patients With Symptomatic Irreversible Pulpitis Compared to Placebo, Using VAS Scores and Analgesic Intake Over 48 Hours.CompletedNCT07239505Not applicable1 country
- Comparison of Clinical Outcomes Between GentleWave® and Biolase®CompletedNCT05555043Not applicable1 country
- Effect of Photobiomodulation to Reduce Post-operative Pain After Endodontic SurgeryCompletedNCT05935306Not applicable1 country
- Effect of Different Bioactive Restorative Materials and Techniques on Pulpal ConditionCompletedNCT07715383Not applicable1 country
- "Postoperative Pain Following Laser-Assisted Root Canal Treatment: A Randomized Clinical Trial"CompletedNCT06129643Phase 21 country
- Postural and Muscle Fatigue Analysis of Endodontic ResidentsCompletedNCT062826531 country
- Revascularisation of Autotransplanted TeethCompletedNCT052672491 country
- The Ability of Brain Waves Activity to Detect Patient Susceptibility to Post-Operative PainCompletedNCT074456331 country