An interventional study of Indirect Pulp Treatment in Deep Caries Lesion of Primary Teeth, Dental Pulp Diseases and Deep Proximal Caries, sponsored by Cairo University. Not yet recruiting. Open to participants aged 3 Years to 7 Years. Per ClinicalTrials.gov, last updated 2024-11-05.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Among 59 studies in Pulpitis by Cairo University — 19 open to participants now, 19 under way, none of them phase 3. Pulpitis · Cairo University.
Among the 59 studies in Pulpitis by Cairo University, this one is the 30th largest by planned enrollment of the 58 interventional ones that give a count, is one of 3 that started in 2024, is one of 44 with no phase, reaches primary completion later than 9 of the 18 other live ones, and was the 46th registered.
316 studies on the registry are indexed under Pulpitis; 90 are open to participants now.
Browse Pulpitis studies →19 of the 59 studies in Pulpitis by Cairo University are open now, in 1 country. Recruiting first, the newest first:
Cairo University · Sites in Egypt
Ages 4–6 · Healthy volunteers
Cairo University · Sites in Egypt
Ages 4–9 · Healthy volunteers
Cairo University · Sites in Egypt
Ages 14–32 · Healthy volunteers
Cairo University
Ages 14–50 · Healthy volunteers
Cairo University
Ages 18–60
By country, each count listing its studies:
Of the 41 Pulpitis studies recruiting now, 9 (22%) set no upper age limit and 32 (78%) stop at 75 or younger; 19 take children under 18; 24 take healthy volunteers.
This study: 3 Years to 7 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
59 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 5 · Phase 2 7 · Phase 3 6 · Phase 4 3
First in 2012; this study’s year is marked. 3 started in 2024.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 50 is below the median of 64 across 288 interventional studies indexed under Pulpitis.
Median enrollment 51 across the 58 interventional studies, 50 across the 1 observational. Of the 22 that completed or were terminated, 0 (0%) have results posted.
This tab as a report to print or save as PDF → With an account.
Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
6 of the studies in Pulpitis by Cairo University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07701551Cairo UniversityHypertonic Saline as a Final Flush and Post-Operative Pain After Single Visit Root Canal Treatment in Mandibular Premolar. | 2027-01-01 |
| NCT07196683Cairo UniversityRegenerative Potentials of Mature Mandibular Molars With Symptomatic Irreversible Pulpitis Enhanced With Different Scaffolds | 2027-01-01 |
| NCT07415694Cairo UniversityChild's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars | 2027-01-25 |
| NCT07522723Cairo UniversityClinical and Radiographic Assessment of Bio C Repair, Biodentine and Mineral Trioxide Aggregate | 2027-04 |
| NCT07743372Cairo UniversityEffect of Preoperative Diclofenac Potassium Dose on Endodontic Pain | 2027-08 |
Among the 59 studies in Pulpitis by Cairo University, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The following study will be created to evaluate how the location of caries affects the effectiveness of indirect pulp treatment in primary molars. aiding in the development of evidence-based recommendations for pediatric dentists.
A selective case study design will be employed, focusing on primary molars with either occlusal or proximal carious lesions. Children aged between 3 to 7 years meeting the inclusion criteria will be examined clinically and radiographically to assess the extent and location of the carious lesion. Two groups will be involved in the study; primary molars will be submitted to each group based on whether the lesion is proximal or occlusal. Both groups will then receive indirect pulp therapy, and a clinical and radiographic evaluation for one year will be conducted.
The purpose of this study is to examine how the location of caries, whether proximal or occlusal, affects the success rate of IPT in primary molars. Understanding this relationship is essential for developing more tailored clinical approaches in pediatric dentistry to ensure long-term treatment success.
316 studies on the registry are indexed under Pulpitis; 90 are open to participants now.
This study's planned enrollment of 50 is below the median of 64 across 288 interventional studies indexed under Pulpitis.
Browse Pulpitis studies →Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Compared within Pulpitis, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Dental Pulp Diseases. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Participant criteria:
Teeth criteria:
Exclusion Criteria:
Clinical signs or symptoms suggesting evidence of pulp degeneration or a non -vital tooth such as:
Presence of the following Radiographic criteria:
In primary molars with deep proximal caries indirect pulp treatment will be performed by removing infected dentin while affected dentin in pulpal floor will be left in place. Teeth will be capped by a dressing material.
Procedure: Indirect Pulp Treatment
In primary molars with deep occlusal caries also IPT will be performed. Soft infected dentin will be carefully removed until the dried, hardened affected dentin with a leathery consistency reached then teeth will be capped by a dressing material
Procedure: Indirect Pulp Treatment
Indirect pulp treatment is considered one of the most conservative pulp therapies, which preserves the pulp's vitality in teeth with reversible pulpitis. It has been chosen to be the intervention in both groups as the aim of this study is to assess the impact of caries location (proximal vs. occlusal caries) in influencing the success rate of IPT.
Clinical success rate of primary molars with deep occlusal or proximal caries treated by Indirect Pulp Treatment (IPT)
Clinical success rate will be assess through assessment of the following : Post-operative Pain (percentage of absence of pain), Presence or absence of clinical signs (e.g., swelling, abscess, sinus tract), and Pain on Percussion
Time frame: one year follow up
Radiographic success rate of primary molars with deep occlusal or proximal caries treated by Indirect Pulp Treatment (IPT).
Radiographic Success Rate will be assess every (6, and 12 months) through assessment of the following in the x-ray film : No radiographic evidence of periapical or inter-radicular radiolucency, No internal or external root resorption, No furcation involvement, and No widening in the periodontal membrane ligament )
Time frame: one year follow up
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
Start is estimated for Dec 2024; primary completion for Aug 2026, 20 months later.
Of 158 non-industry interventional studies with no phase under Pulpitis, half reached primary completion within 16 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 28. This study's planned 20 months is above that.
Counting every sponsor, half of 158 studies reached it within 16 months; a quarter within 9 and three quarters within 28.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.
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