Lewy Body Disease clinical trials
The registry lists 239 studies for Lewy Body Disease across more than 10 countries. 88 are recruiting or about to start. 84 of them are mainly about Lewy Body Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Status
Who runs them
Mayo Clinic (8) · University Hospital, Strasbourg, France (7) · Axovant Sciences Ltd. (6) · Skane University Hospital (6) · Eisai Co., Ltd. (5) · University College, London (5) · Georgetown University (5) · University of Pennsylvania (5)
What is being tested here
Drugs under test in Lewy Body Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ambroxol | 2 | 0 | 2 |
| Fluorodopa F 18 | 2 | 1 | 2 |
| Pimavanserin | 1 | 1 | 2 |
| 3-Iodobenzylguanidine | 1 | 0 | 1 |
| Pittsburgh compound B | 1 | 0 | 1 |
| Terazosin | 1 | 0 | 1 |
| Donanemab | 1 | 0 | 1 |
| Quetiapine | 1 | 0 | 1 |
| Donepezil | 0 | 1 | 6 |
| VX-745 | 0 | 0 | 3 |
Drug classes tested here Cholinesterase inhibitors 7 · Tyrosine kinase inhibitors (TKIs) 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026PET Imaging Evaluation of [11C]SY08 · Massachusetts General Hospital
- Nov 2026Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling · University Health Network, Toronto
- Dec 2026[18F]ACI-15916 PET in α-synucleinopathies · AC Immune SA
- Dec 2026ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing · Sunnybrook Health Sciences Centre
- Dec 2026ANeED Joint Effort 21: eHealth and a PPI Program in Dementia With Lewybodies (DLB) · University of Bergen
- Dec 2026Natural History Study of Synucleinopathies · NYU Langone Health
- Dec 2026The Swedish BioFINDER - Memory Clinic Study · Skane University Hospital
- Dec 2026Retinal Imaging in Neurodegenerative Disease · Duke University
- Dec 2026Language and Lewy Body Diseases: Sentence Comprehension Problems and Modifying Noninvasive Brain Stimulation Treatment · Masaryk University
- Jan 2027DC Longitudinal Study on Aging and Specimen Bank · Georgetown University
Who these studies take
Of the 63 Lewy Body Disease studies recruiting now, 41 (65%) set no upper age limit and 0 (0%) stop at 75 or younger. 10 (16%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 31 (49%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 10 (16%) | 10 (16%) |
| 18 | 35 (56%) | 35 (56%) |
| 30 | 40 (63%) | 40 (63%) |
| 40 | 42 (67%) | 42 (67%) |
| 50 | 55 (87%) | 55 (87%) |
| 65 | 63 (100%) | 63 (100%) |
| 75 | 63 (100%) | 63 (100%) |
| 85 | 59 (94%) | 59 (94%) |
Across all 239 studies, recruiting or not: 3% stop at 75 or younger and 1% at 65; 10% take children; <1% are for women only and <1% for men only; 41% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lewy Body Disease studies take
Of 24 phase 2 interventional studies under Lewy Body Disease, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 26 mo16–45 · 24 studies | — | — |
| Interventional, no phase | 35 mo26–61 · 63 studies | — | 34 mo26–53 · 59 studies |
| Observational | 81 mo40–171 · 45 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting2
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 239. Browse all 239 → or search them.
- VOCALE LBD: Online Peer Support for Caregivers of People With Lewy Body DementiaRecruitingNCT07637097Not applicable1 country
- Early Molecular Biomarkers for Differentiating Parkinsonian SyndromesEnrolling by invitationNCT076048831 country
- Transcranial Alternating Current Stimulation in Lewy Body DementiaRecruitingNCT07375771Not applicable1 country
- Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia PsychosisRecruitingNCT07029581Phase 26 countries
- A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)RecruitingNCT07589595Phase 24 countries
- Phase 3, Open Label Extension Study of ACP-204 in Lewy Body Dementia PsychosisRecruitingNCT07095465Phase 36 countries
- Automated Language Analysis in Neurodegenerative Diseases: Application of Artificial Intelligence ModelsRecruitingNCT07906769Not applicable1 country
- OCT-Angiography and Adaptive Optics in Patients With Memory ImpairmentRecruitingNCT04389437Not applicable1 country
- [18F]ACI-15916 PET in α-synucleinopathiesRecruitingNCT06891703Early Phase 11 country
- Evaluating How Red-light Therapy Applied to the Head Affects Symptoms, Daily Life, and Brain Activity in People With Dementia With Lewy BodiesRecruitingNCT07602296Not applicable1 country
- Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's DiseaseRecruitingNCT030197571 country
- Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy BodiesNot yet recruitingNCT072408051 country
- Rhythmic Entrainment and Alertness in Lewy Body DementiaNot yet recruitingNCT07846189Not applicable
- Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential AnalysisRecruitingNCT06439355Not applicable1 country
- Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative DiseasesRecruitingNCT05326750Not applicable1 country
- Visual Hallucinations in Lewy Body DiseasesRecruitingNCT078494131 country
- Pulsed Electromagnetic Field Treatment With Dementia PatientsRecruitingNCT06862557Not applicable1 country
- Multi-Center Study of Natural History in Atypical Parkinsonian Syndromes (MAPS-NH)RecruitingNCT078059671 country
- Neurodegenerative Diseases Progression Markers (MARKERS-NDD)RecruitingNCT065967461 country
- Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)Not yet recruitingNCT072007391 country
- Biofluid Research on Age-Related or Inherited NeurodegenerationRecruitingNCT077987001 country
- ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea TestingRecruitingNCT04335994Not applicable1 country
- MIBG in Aging and Neurologic DisordersEnrolling by invitationNCT05514106Phase 41 country
- 18F-mFBG Cardiac Uptake With Lewy Body DementiaRecruitingNCT07176286Phase 21 country
- Neurologic Stem Cell Treatment StudyRecruitingNCT02795052Not applicable2 countries
- Imaging of Brain Amyloid Plaques in the Aging PopulationEnrolling by invitationNCT00950430Phase 41 country
- Alpha-synuclein Education and Disclosure in Individuals With Preclinical and Symptomatic Lewy Body DiseaseNot yet recruitingNCT076466521 country
- Natural History Study of SynucleinopathiesRecruitingNCT017999154 countries
- Dementia With Lewy Bodies: Clinical Symptoms, Biomarkers and ProgressionRecruitingNCT076293491 country
- Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related DementiasEnrolling by invitationNCT04786223Phase 21 country
- Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.Enrolling by invitationNCT07595666Not applicable1 country
- North American Prodromal Synucleinopathy Consortium Stage 2Enrolling by invitationNCT058264572 countries
- Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical TrialRecruitingNCT04588285Phase 21 country
- Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental DisordersEnrolling by invitationNCT072398431 country
- Retinal Hyperspectral Imaging in Neurodegenerative DiseasesRecruitingNCT07545473Not applicable1 country
- The Swedish BioFINDER Sleep StudyRecruitingNCT075337991 country
- The Swedish BioFINDER 2 StudyRecruitingNCT03174938Not applicable1 country
- The Swedish BioFINDER - Memory Clinic StudyRecruitingNCT061224151 country
- The Swedish BioFINDER - Primary Care StudyRecruitingNCT061203611 country
- Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic DisordersRecruitingNCT07509125Not applicable1 country
- Longitudinal Imaging Biomarkers of Disease Progression in DLBEnrolling by invitationNCT03582488Phase 41 country
- [18F]F-DOPA Imaging in Patients With Autonomic FailureRecruitingNCT04246437Phase 11 country
- Social-cognitive Functioning: Validation of a New Neuropsychological TestRecruitingNCT05558709Not applicable1 country
- Terazosin for Dementia With Lewy BodiesNot yet recruitingNCT04760860Phase 1/21 country
- Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body DementiaRecruitingNCT07284290Phase 41 country
- Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental DisorderEnrolling by invitationNCT073141901 country
- Circadian Rhythm and Other Factors in Memory Clinic PatientsRecruitingNCT059777121 country
- 18F-DOPA II - PET Imaging OptimizationRecruitingNCT04706910Phase 31 country
- Language and Lewy Body Diseases: Sentence Comprehension Problems and Modifying Noninvasive Brain Stimulation TreatmentRecruitingNCT05847985Not applicable1 country
- Retinal Imaging in Neurodegenerative DiseaseRecruitingNCT032336461 country