An observational study in Spinal Deformity, sponsored by The University of Hong Kong. Recruiting at 1 site in Hong Kong. Open to participants aged 10 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-05-01.
Sponsored by The University of Hong Kong · Observational
The investigators aim to use artificial intelligence (AI) to help clinicians in diagnosing and assessing spinal deformities.
Background Spinal deformity is a prevalent spinal disorder in both paediatric and adult populations. The spine alignment need to be quantitively assessed for further treatment planning. However, the current practice requires spine surgeons to manually place landmarks of endplates and key vertebrae. The process is laborious and prone to inter- and intra-rater variance. Thus, the investigators have developed an AI-powered spine alignment assessment system (AlignProCARE) to facilitate clinicians in fast, accurate and consistent analytical results.
The investigators aim to test and improve the performance of the spine alignment auto-analysis in all patients with spinal deformities in multiple centers including Malaysia, China, and Japan
Objectives:
4 Qualitatively analyse the AlignProCARE+ using an independent dataset.
660 studies on the registry are indexed under Scoliosis; 186 are open to participants now.
This study's planned enrollment of 2,500 is above the median of 84 across 256 observational studies indexed under Scoliosis.
Browse Scoliosis studies →The University of Hong Kong is the lead sponsor of 1,292 studies on the registry; 348 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Compared within Scoliosis, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Congenital Abnormalities. The counts are of registry records indexed under each term, refreshed daily. How we classify →
All subjects with spinal deformities
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Routine care of patients with spinal deformities
Other: Nude back photo
Nude back photo at baseline and at follow-ups for each patient and visual severity and curve type classifications
Cobb angle
Coronal Cobb angle of the spinal deformity. The most tilted end vertebrae away from the apex will be used for measurement of the Cobb angle.The anteroposterior radiograph is used to assess
Time frame: 1 year
Thoracic kyphosis
Thoracic kyphosis T5-12: angle between upper endplate of T5 to lower endplate of T12 in the lateral radiograph
Time frame: 1 year
Lumbar lordosis
Lumbar lordosis L1-S1: angle between upper endplate of L1 to top of S1 in the lateral radiograph
Time frame: 1 year
Pelvic tilt
Pelvic tilt angle measurement in degrees in the lateral radiograph
Time frame: 1 year
Sacral slope
Sacral slope angle measurement in degrees in the lateral radiograph
Time frame: 1 year
Pelvic incidence
Pelvic incidence angle measurement in degrees in the lateral radiograph
Time frame: 1 year
Maximum thoracic kyphosis
Maximum thoracic kyphosis: angle measurement from the upper endplate of most tilted upper end vertebra to the lower endplate of the lower end vertebra of the thoracic spine in the sagittal plane radiograph
Time frame: 1 year
Curve severity
Severity classifications: normal-mild; moderate and severe
Time frame: 1 year
Plan to share: No
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