Cholecystitis clinical trials
The registry lists 192 studies for Cholecystitis across more than 10 countries. 36 are recruiting or about to start. 109 of them are mainly about Cholecystitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-16. Counting its narrower condition Cholecystitis, Acute too: 305 studies, 61 open.
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Who runs them
Assiut University (8) · Hepatopancreatobiliary Surgery Institute of Gansu Province (4) · Sohag University (4) · Medipol University (3) · Seoul St. Mary's Hospital (3) · University Hospital, Geneva (3) · Sisli Hamidiye Etfal Training and Research Hospital (3) · Bayer (2)
What is being tested here
Drugs under test in Cholecystitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 1 | 1 | 2 |
| Bupivacaine | 1 | 0 | 2 |
| Lidocaine | 1 | 1 | 1 |
| Ondansetron | 0 | 0 | 2 |
| Indocyanine Green | 0 | 0 | 2 |
| Tigecycline | 0 | 0 | 2 |
| Ceftriaxone | 0 | 0 | 2 |
| Metronidazole | 0 | 0 | 2 |
| Doripenem | 0 | 2 | 2 |
| Gabapentin | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Nov 2026Ultrasound-Guided Rectus Sheath Block Versus Local Infiltration · Sisli Hamidiye Etfal Training and Research Hospital
- Dec 2026A Strategy for Gallstone Expulsion Through Dietary Therapy · Hepatopancreatobiliary Surgery Institute of Gansu Province
- Dec 2026STALL vs Sole Local Wound Infiltration in Laparoscopic Cholecystectomy · Helsinki University Central Hospital
- Dec 2026Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis · Peking University Third Hospital
- May 2027One vs. Two Stents for Gallbladder Disease · Mayo Clinic
- Jul 2027Indocyanine Green Fluorescence During Fundus First Laparoscopic Cholecystectomy · Karolinska Institutet
- Aug 2027SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis · European Society for Trauma and Emergency Surgery
Who these studies take
Of the 22 Cholecystitis studies recruiting now, 13 (59%) set no upper age limit and 7 (32%) stop at 75 or younger. 2 (9%) take children under 18. 0 (0%) are for women only and 1 (5%) for men only; 5 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (5%) | 1 (5%) |
| 18 | 20 (91%) | 21 (95%) |
| 30 | 21 (95%) | 22 (100%) |
| 40 | 21 (95%) | 22 (100%) |
| 50 | 19 (86%) | 20 (91%) |
| 65 | 19 (86%) | 20 (91%) |
| 75 | 15 (68%) | 16 (73%) |
| 85 | 14 (64%) | 15 (68%) |
Across all 192 studies, recruiting or not: 30% stop at 75 or younger and 20% at 65; 15% take children; 2% are for women only and 1% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cholecystitis studies take
Of 64 interventional studies with no phase under Cholecystitis, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 18 mo7–26 · 64 studies | — | 18 mo7–26 · 60 studies |
| Observational | 35 mo10–57 · 23 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting1
- Ultrasound-Guided Rectus Sheath Block Versus Local InfiltrationOct 16, 2026NCT07582029
Newly registered1
- Prophylactic TAP Block in Laparoscopic CholecystectomyOct 13, 2026NCT07871617
Studies
Recruiting first, then most recently updated. Showing 50 of 192. Browse all 192 → or search them.
- Ultrasound-Guided Rectus Sheath Block Versus Local InfiltrationRecruitingNCT07582029Not applicable1 country
- STALL vs Sole Local Wound Infiltration in Laparoscopic CholecystectomyRecruitingNCT06123117Not applicable1 country
- SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous CholecystitisNot yet recruitingNCT075680801 country
- Shortwave Infrared Surgical Imaging Device StudyEnrolling by invitationNCT077444251 country
- Probiotic Yogurt in Patients With Chronic CholecystitisNot yet recruitingNCT07654985Not applicable1 country
- Ultrasound for Postop Lung Issues in Low-Flow AnesthesiaRecruitingNCT068245061 country
- Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating RoomRecruitingNCT074736871 country
- A Strategy for Gallstone Expulsion Through Dietary TherapyRecruitingNCT06699030Not applicable1 country
- One vs. Two Stents for Gallbladder DiseaseRecruitingNCT07222527Not applicable1 country
- Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct StonesRecruitingNCT07008170Not applicable1 country
- Indocyanine Green Fluorescence During Fundus First Laparoscopic CholecystectomyNot yet recruitingNCT06918210Not applicable
- Surgical vs Endoscopic Treatments as ImmunoModulating Interventions in High-Risk Acute Calculous CholecystitisRecruitingNCT06918652Not applicable1 country
- CHOLE-POSSUM PRO Validation for Prediction of Mortality After Cholecystectomy for Acute Calculous Cholecystitis: Protocol for a Prospective Multicenter Observational StudyRecruitingNCT069089801 country
- Posterior Wall Sparing of Laparoscopic Cholecystectomy in Cirrhotic PatientsNot yet recruitingNCT06778928
- Desflurane Potentially Induces Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Perioperative Procedures by Modulating Cdc42 and Clock ProteinsNot yet recruitingNCT06772558Not applicable1 country
- Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic ChlolecystectomyRecruitingNCT06740903Phase 2/31 country
- Intraoperative Hyperspectral Imaging for Laparoscopic SurgeryNot yet recruitingNCT06700317Not applicable
- EOIB for Laparoscopic CholecystectomyRecruitingNCT06656299Not applicable1 country
- Dutch Cholecystitis Snapshot StudyRecruitingNCT063498631 country
- An Assessment of the Effectiveness (Efficacy) of Odeston (Odeston®) in Patients With Chronic Cholecystitis in Real Medical PracticeNot yet recruitingNCT065167181 country
- ALgerian Cholecystectomy Outcomes and Determinants Study (AL-CODS)Not yet recruitingNCT06481007
- Optimal Timing for Laparoscopic Cholecystectomy After Cholecystostomy in Acute Cholecystitis Tokyo II/III SettingRecruitingNCT06476054Not applicable1 country
- A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone DiseaseRecruitingNCT06405906Not applicable1 country
- Food Effect on the Bioavailability of 4-MUST, Tablets, 128 mgRecruitingNCT06342804Phase 11 country
- Prospective Evaluation of Ultrasound-guided Percutaneous Cholecystostomy With the Trocar TechniqueRecruitingNCT063306881 country
- Safety, Tolerability and Pharmacokinetics of 4-MUST, Tablets, 128 mg (Valenta Pharm JSC) During Single and Multiple Oral Administration in Healthy VolunteersRecruitingNCT06315387Phase 11 country
- Complications of Cholecystostomy in ACCNot yet recruitingNCT06227936
- Body First Approach in Lap Cholecystectomy in Cases With Obscure Calot's TriangleNot yet recruitingNCT06280404
- Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic CholecystectomyRecruitingNCT05775133Not applicable1 country
- Outcomes of Three Ports Versus Four Ports Laparoscopic Cholecystectomy, Sohag General Surgery Department ExperienceEnrolling by invitationNCT062641151 country
- Comparison of the Effects of Different PEEP Values With USG on Optic Nerve Sheath DiameterNot yet recruitingNCT06224868Not applicable
- Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy CasesRecruitingNCT060364981 country
- Modified Laparoscopic Transcystic Biliary Drainage in the Management of CholecystocholedocholithiasisNot yet recruitingNCT06011941Not applicable1 country
- preGallstep - A Clinical Pilot TrialRecruitingNCT04801238Not applicable1 country
- Predictors of Difficult Laparoscopic Cholecystectomy, Scoring Systems and Their Implications on the Outcomes , Sohag Experience.RecruitingNCT05859607Not applicable1 country
- Endosonography-guided Gallbladder Drainage vs Non-endoscopic Treatment in Inoperable Acute CholecystitisRecruitingNCT05702775Not applicable1 country
- Prophylactic TAP Block in Laparoscopic CholecystectomyCompletedNCT07871617Not applicable1 country
- Comparison Between Oral Gabapentin Versus Diclofenac Sodium in Post-operative Analgesia Laparoscopic CholecystectomyCompletedNCT07131527Not applicable1 country
- Cystic Artery Preservation : an Additional Step for Safe Laparoscopic CholecystectomyCompletedNCT07339501Not applicable1 country
- Mallampati Score for Prediction and Prognosis of Postoperative Mortality and Morbidity and Safety Profiles of Patients Undergoing Laparoscopic Cholecystectomy in Qassim RegionCompletedNCT060057011 country
- Video Laryngeal Mask Versus Endotracheal Tube Undergoing Laparoscopic Cholecystectomy SurgeryCompletedNCT06502028Not applicable1 country
- Efficacy Of M-TAPA and TAP Block Following Laparoscopic CholecystectomyCompletedNCT06198335Not applicable1 country
- Prospective Evaluation of an Endoscopic Ultrasound (EUS)-Based Artificial Intelligence to Assist in the Deployment of Lumen Apposing Metal Stents for Gallbladder DrainageCompletedNCT069810521 country
- Clipless Versus Conventional Laparoscopic Cholecystectomy Using Harmonic ScalpelCompletedNCT07473388Not applicable1 country
- Fundus-first Laparoscopic CholecystectomyCompletedNCT07137546Not applicable1 country
- Role of Intra-Operative Aspiration in Distended GB in LCCompletedNCT07378410Phase 31 country
- Investigation of the Effects of Aromatherapy Foot Massage on Postoperative Pain, Sleep, and Recovery in Laparoscopic CholecystectomyCompletedNCT07363668Not applicable1 country
- Genomic Resources for Enhancing Available Therapies (GREAT1.0) StudySuspendedNCT043069391 country
- Metabolic Dysfunction-Associated Fatty Liver Disease Impairs Intraoperative Indocyanine Green Fluorescence Cholangiography Quality: Development and Validation of a Predictive ModelCompletedNCT072972251 country
- Evaluation of Ultra-portable Ultrasound in General PracticeCompletedNCT04127149Not applicable1 country