ClinicalTrials.gg
RecruitingNCT06824506Updated Jun 5, 2026

Ultrasound for Postop Lung Issues in Low-Flow Anesthesia

An observational study in Atelectasis, Postoperative, Cholecystitis; Gallstone and Pulmonary Atelectasis, sponsored by Ankara Ataturk Sanatorium Training and Research Hospital. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-05.

Sponsored by Ankara Ataturk Sanatorium Training and Research Hospital · Observational

From the registry’s dates

  • Started Feb 2025; still recruiting 1 year 8 months later.
Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
110
Ages
18 Years and older
Sex
All
01

Study summary

Detecting possible atelectasis and other respiratory problems that may develop immediately after extubation via lung ultrasonography can reduce pulmonary complications by performing necessary interventions such as oxygen support, respiratory exercises, mobilization, and non-invasive mechanical ventilation applications at an early stage. In addition, although low-flow anesthesia is frequently used in daily anesthesia practice, publications showing the effects of its use in laparoscopic cholecystectomy operations on pulmonary complications are limited. On this occasion, this study can be presented as a contribution to the literature.

Read the detailed description

Postoperative atelectasis is a common complication that can develop in all patients receiving general anesthesia. The frequency of atelectasis increases due to increased intraabdominal pressure, especially in laparoscopic surgeries performed with pneumoperitoneum. For this reason, in order to prevent postoperative complications related to the lungs, it is extremely important to recognize atelectasis at an early stage, as well as to recognize the mechanisms that will cause atelectasis and avoid them.

Lung ultrasonography (Lung USG) draws attention for the rapid, cheap, safe and reliable detection of postoperative atelectasis. The fact that it can be applied at the bedside and can be easily repeated makes this method valuable. In the literature and in daily practice, it is seen that anesthesiologists commonly apply inhalation anesthesia with different fresh gas flow (FGF) rates during general anesthesia.

As defined by Baker and Simionescu, in low-flow anesthesia, FGF varies between 0.5 and 1 liter per minute. It has been shown that all types of flow are safe with modern anesthesia machines.

This study aims to demonstrate the effect of low-flow anesthesia (LFA) on pulmonary complications and, in particular, atelectasis that may develop after laparoscopic cholecystectomy operations, using a non-invasive, rapidly applicable, and proven method such as Lung USG.

02

Conditions studied

  • Atelectasis, Postoperative
  • Cholecystitis; Gallstone
  • Pulmonary Atelectasis

Keywords

  • lung ultrasound
  • low flow anesthesia
  • laparoscopic cholecystectomy
03

In context

Pulmonary Atelectasis

377 studies on the registry are indexed under Pulmonary Atelectasis; 93 are open to participants now.

This study's planned enrollment of 110 is above the median of 76 across 100 observational studies indexed under Pulmonary Atelectasis.

Browse Pulmonary Atelectasis studies →

Lead sponsor

Ankara Ataturk Sanatorium Training and Research Hospital is the lead sponsor of 38 studies on the registry; 15 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All cases that meet the inclusion and exclusion criteria will be included in the study. Patients will be taken to the operating room after being preoperatively evaluated in the observation room. The patient's anesthetic management will be provided by another anesthesiologist who is not participating in the study and is responsible for the patient. Intraoperative data will be obtained from the patient's anesthesia follow-up form and the records of the anesthesia machine. When the patients arrive in the recovery room, postoperative ultrasonographic measurements and other evaluations will be performed and noted. This group will include patients who received general anesthesia using low-flow techniques during the intraoperative period.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with
  • Patients scheduled for laparoscopic cholecystectomy
  • Patients with a between 18-35 kg/m²
  • Patients in the (ASA) 1-2-3 category

Exclusion criteria

Exclusion Criteria:

  • Patients with emergency surgery planned
  • Patients with ASA 4 and above
  • Patients with lung disease
  • Patients who have undergone thoracic surgery
  • Pregnancy
  • Patients with a preoperative Lung Ultrasound Score of 2 or 3 in any lung region
Terms in these criteria, in plain language(3)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

ASA physical status

The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.

05

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
110 participants (estimated)
Patient registry
No

Groups and cohorts

  • Low-Flow Anesthesia Group

    As this study is observational in nature, no interventions will be performed by the research team. The study will involve a single group, within which the incidence and prevalence of the outcomes will be assessed.

    Other: No-intervention

Interventions

  • OtherNo-intervention

    No interventions will be performed by the research team.

06

What researchers measure

Primary outcomes

  1. incidence of postoperative atelectasis

    Incidence of postoperative atelectasis determined by lung ultrasonography in patients undergoing laparoscopic cholecystectomy with low-flow anesthesia

    Time frame: 1 hour peroperatively

Secondary outcomes

  1. incidence of other postoperative pulmonary complications

    Other postoperative pulmonary complications that may develop and be detected by ultrasonography such as pneumothorax, pleural effusion, pulmonary edema

    Time frame: 1 hour peroperatively

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 5, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06824506
Lead sponsor
Ankara Ataturk Sanatorium Training and Research Hospital
Responsible party
Mustafa Özgür Cirik (Assoc. Prof., Ankara Ataturk Sanatorium Training and Research Hospital) — Principal investigator
First posted
Feb 13, 2025
Start date
Feb 15, 2025
Primary completion
Mar 31, 2025
Completion
Jun 15, 2026 (estimated)
Last update
Jun 5, 2026

Study contacts

Hilal SAZAK, MD
Contact
hilalgun@yahoo.com
+90 312 356 90 00
Necla DERELI, MD
Contact
Mustafa Özgür CIRIK, MD
principal investigator · Ankara Ataturk Sanatorium Training and Research Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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