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Breakthrough Pain clinical trials

The registry lists 34 studies for Breakthrough Pain across more than 10 countries. 4 are recruiting or about to start. 21 of them are mainly about Breakthrough Pain (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-18.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
19
Terminated
5
Recruiting
3
Active, not recruiting
3
Withdrawn
2
Not yet recruiting
1

Phase

Phase 3
10
Phase 4
5
Phase 1
4
Phase 2
3

Where

United States
9
Spain
6
Germany
2
Singapore
2
United Kingdom
2
France
2

Who runs them

Cephalon (6) · Angelini Farmacéutica (3) · KK Women's and Children's Hospital (2) · Kyowa Kirin Co., Ltd. (2) · Holy Family Hospital, Nazareth, Israel (2) · University of Surrey (1) · UNICANCER (1) · Alexza Pharmaceuticals, Inc. (1)

What is being tested here

Drugs under test in Breakthrough Pain studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Fentanyl2715
Bupivacaine203
Ropivacaine022
Methadone001
Tramadol001
Acetaminophen001

Drug classes tested here Opioids 2 open · Local anesthetics 2 open

Coming up

2phase 3 studies under way
2studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 2

Who these studies take

Of the 3 Breakthrough Pain studies recruiting now, 3 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 2 (67%) take children under 18. 3 (100%) are for women only and 0 (0%) for men only; 2 (67%) take healthy volunteers.

Recruiting studies that take each age, of 3
AgeWomenMen
102 (67%)0 (0%)
183 (100%)0 (0%)
303 (100%)0 (0%)
403 (100%)0 (0%)
503 (100%)0 (0%)
653 (100%)0 (0%)
753 (100%)0 (0%)
853 (100%)0 (0%)

Across all 34 studies, recruiting or not: 15% stop at 75 or younger and 12% at 65; 18% take children; 18% are for women only and 0% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 34 of 34. search them.