Blepharitis clinical trials
The registry lists 73 studies for Blepharitis across more than 10 countries. 9 are recruiting or about to start. 54 of them are mainly about Blepharitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.
Get an email when these change. Save the Blepharitis studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Merck Sharp & Dohme LLC (7) · Tarsus Pharmaceuticals, Inc. (5) · Federal University of São Paulo (2) · Alcon Research (2) · Laboratoires Thea (2) · Aperta Biosciences, LLC (2) · University of Texas Southwestern Medical Center (2) · Nicox Ophthalmics, Inc. (2)
What is being tested here
Drugs under test in Blepharitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Spinosad | 1 | 0 | 2 |
| Azithromycin | 0 | 0 | 10 |
| TP-03 | 0 | 2 | 3 |
| Loteprednol Etabonate | 0 | 1 | 3 |
| Lotilaner | 0 | 1 | 2 |
| Tobramycin | 0 | 1 | 2 |
| Moxifloxacin | 0 | 1 | 2 |
| Dexamethasone | 0 | 1 | 2 |
| Moxidectin | 0 | 0 | 1 |
| Fluticasone | 0 | 0 | 1 |
Drug classes tested here Corticosteroids 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Jan 2027A Phase 2 Study to Compare Efficacy and Safety of a Novel Topical Therapy (APT-001, Spinosad 1.8%) in Patients With Blepharitis · Aperta Biosciences, LLC
- Mar 2027Clinical Lid Eradication of Antifungal-Responsive FUNGUS Study · Brent Kramer
- Mar 2027Ocular Dysbiosis in Eyelid Disease · Brent Kramer
Who these studies take
Of the 6 Blepharitis studies recruiting now, 6 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 6 (100%) | 6 (100%) |
| 30 | 6 (100%) | 6 (100%) |
| 40 | 6 (100%) | 6 (100%) |
| 50 | 6 (100%) | 6 (100%) |
| 65 | 6 (100%) | 6 (100%) |
| 75 | 6 (100%) | 6 (100%) |
| 85 | 6 (100%) | 6 (100%) |
Across all 73 studies, recruiting or not: 7% stop at 75 or younger and 4% at 65; 14% take children; 0% are for women only and 0% for men only; 16% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 73. Browse all 73 → or search them.
- A Phase 2 Study to Compare Efficacy and Safety of a Novel Topical Therapy (APT-001, Spinosad 1.8%) in Patients With BlepharitisNot yet recruitingNCT07904767Phase 21 country
- Ocular Dysbiosis in Eyelid DiseaseRecruitingNCT078694981 country
- Clinical Lid Eradication of Antifungal-Responsive FUNGUS StudyNot yet recruitingNCT07856680Phase 41 country
- Development of a Mobile Terminal-Based Intelligent Detection System for Multiple Anterior Segment Diseases of the EyeRecruitingNCT076349131 country
- Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex BlepharitisRecruitingNCT07400965Phase 21 country
- Photobiomodulation With REd vs BluE Light (REBEL)RecruitingNCT06371300Not applicable2 countries
- A Usability Study of iTEAR100 For Combined EyeLid Microblepharoexfoliation and NeurostimulationRecruitingNCT06235450Phase 11 country
- BroadBand Light for the Treatment of Dry Eye DiseaseNot yet recruitingNCT06174064Not applicable
- Evaluation of SUMMIT BRUSH in Treatment of BlepharitisRecruitingNCT04603222Not applicable1 country
- A Phase 2, Controlled, Double Blind, Randomized and Multicenter Study to Compare Efficacy and Safety of a Novel Topical Therapy (APT-001, Spinosad 1.8%) in Patients With Blepharitis.CompletedNCT06720896Phase 21 country
- Demodex Blepharitis in Scleral Lens WearersCompletedNCT07561450Phase 41 country
- Performance and Safety of IRIDIUM GARZE in Blepharitis or Blepharconjunctivitis Adjuvant TreatmentCompletedNCT07431385Not applicable1 country
- Sterile Plant-Based Gauze for Eyelid Hygiene in Anterior BlepharitisCompletedNCT07759180Not applicable1 country
- Treatment of Blepharitis Induced by Demodex Folliculorum Through Eyelid Cleansing With Wipes Containing Topical ChlorhexidineCompletedNCT07451678Phase 41 country
- A Phase 3 Study to Evaluate the Efficacy and Safety of Pimecrolimus 0.3% Ophthalmic OintmentTerminatedNCT06400511Phase 31 country
- Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGDCompletedNCT05454956Phase 21 country
- Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash InfestationCompletedNCT06795165Phase 41 country
- Impact of XDEMVY® on Demodex Blepharitis in Soft Contact Lens WearersCompletedNCT06182358Phase 41 country
- Comparison Between Continuous and Pulsed Oral Doxycycline Treatment Protocols for Refractory Meibomian Gland DysfunctionCompletedNCT065200071 country
- Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA StudyCompletedNCT05629390Phase 31 country
- Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With DemodexActive, not recruitingNCT06054217Phase 21 country
- Innovative Imaging of the Conjunctiva, Cornea, and Ocular AdnexaCompletedNCT02386774Not applicable1 country
- Safety and Efficacy of TP-03 for the Treatment of Demodex BlepharitisCompletedNCT04475432Phase 2/31 country
- Trial to Evaluate the Safety and Efficacy of TP-03 for the Treatment of Demodex BlepharitisCompletedNCT04784091Phase 31 country
- Study Evaluating the Safety and Efficacy of NCX 4251 Ophthalmic Suspension for the Treatment of BlepharitisCompletedNCT04675242Phase 21 country
- Study Evaluating the Safety and Tolerability of NCX 4251 for the Treatment of Acute Exacerbations of BlepharitisCompletedNCT03926026Phase 21 country
- Short-term Effects on Tear Film (Baby Shampoo vs Blephasol)Status unknownNCT04858113Not applicable1 country
- 0.01% Hypochlorous Acid in the Treatment of BlepharitisStatus unknownNCT05608980Not applicable1 country
- Analysis of the Results of Intense Pulsed Light Treatment Previously to Laser Refractive SurgeryStatus unknownNCT05139511Not applicable1 country
- Efficacy of LipiFlow in Patients Affected by Meibomian Gland Dysfunction in Reducing Post-cataract Surgery Dry EyeCompletedNCT05062564Not applicable1 country
- Corneal Epithelial Stem Cells and Dry Eye DiseaseCompletedNCT03302273Not applicable1 country
- Treatment of Blepharitis With Povidone-Iodine 1%Status unknownNCT05160623Not applicable1 country
- Efficacy and Safety Study of a Steroid/Antibiotic Combination Eyedrop to Treat Non-Bacterial BlepharitisCompletedNCT01408082Phase 31 country
- Treatment of Demodex Blepharitis With Ivermectin Gel 0.1% Plus Metronidazole 1%CompletedNCT02236403Phase 31 country
- Efficacy of Over the Counter (OTC) Povidone-Ioldine 5% for Treatment of Acute or Chronic BlepharitisTerminatedNCT01560962Not applicable1 country
- Efficacy and Tolerability of Blephademodex WipesCompletedNCT04780165Not applicable1 country
- Treatment of Patients With Blepharitis and Facial RosaceaCompletedNCT00560703Phase 21 country
- Probiotics for Blepharitis in Adults and ChildrenStatus unknownNCT047428551 country
- Treatment of Anterior Blepharitis With Microblepharoexfoliation ProcedureTerminatedNCT04290455Not applicable1 country
- Safety and Efficacy of KPI-121 in Subjects With Inflammatory Meibomian Gland DiseaseCompletedNCT02218489Phase 21 country
- TTO Swabs Versus Baby Shampoo in Patients With Seborrehic BlepharitisCompletedNCT04678531Phase 41 country
- Ocular Comfort and Inflammation in Lid Hygiene TherapyTerminatedNCT02938078Not applicable1 country
- Lid Wipes Versus Baby Shampoo in Patients With Seborrehic BlepharitisCompletedNCT04441528Phase 41 country
- Facial Demodicosis and Ocular DemodicosisStatus unknownNCT043778411 country
- To Compare Blephapad Combo vs Standard Treatment for Eyelid Cleansing in Bilateral Posterior BlepharitisCompletedNCT03301844Not applicable1 country
- Blephacura Versus Baby Shampoo to Treat BlepharitisCompletedNCT01115192Not applicable1 country
- Treatment of Meibomian Gland Dysfunction Prior to Cataract SurgeryCompletedNCT01808560Not applicable1 country
- DRy Eye Outcome and Prescription StudyStatus unknownNCT036524151 country
- A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye SyndromeCompletedNCT00344721Not applicable1 country
- Antimicrobial and Clinical Efficacy of Cliradex® as Compared With I-Lid'n Lash® Hygiene in Treating BlepharitisStatus unknownNCT03422146Not applicable1 country