Lotilaner clinical trials
How each study uses lotilaner is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the lotilaner studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Approvals
The first approval found in each region, with its record
- United States
- 24 Jul 2023 · XDEMVY · NDA 217603 (FDA, Drugs@FDA)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
5 studies that test it; most in 2022 (2)
| Year | Studies |
|---|---|
| 2021 | 1 |
| 2022 | 2 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 4 · Other 1
Tarsus Pharmaceuticals, Inc. (3) · Boston Sight (1) · LianBio LLC (1)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1
Studies that test lotilaner.
- Dec 2026Study of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE)Phase 2 · Tarsus Pharmaceuticals, Inc.
Studies
Open first, then newest update. How each study uses lotilaner is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 5
- Study of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE)Enrolling by invitationPhase 2Tarsus Pharmaceuticals, Inc.NCT07443202Written as lotilaner
- Demodex Blepharitis in Scleral Lens WearersCompletedPhase 4Boston SightNCT07561450Written as Xdemvy
- A Human Tick Kill Study to Investigate the Safety, Tolerability, and Whole Blood Concentration of TP-05CompletedPhase 2Tarsus Pharmaceuticals, Inc.NCT05387083Written as Low Dose TP-05
- Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA StudyCompletedPhase 3LianBio LLCNCT05629390Written as Lotilaner
- A Pharmacokinetic Study of TP-05 in Healthy SubjectsCompletedPhase 1Tarsus Pharmaceuticals, Inc.NCT05138796Written as TP-05 (lotilaner oral capsules)
As the comparator · 1 — what is tested is compared with lotilaner
Codes
What other systems call lotilaner · ClinicalTrials.gg INT001442
- MeSH (NLM) C000711088lotilanerConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) HEH4938D7KLOTILANERConfirmed FDA, NLM, Wikidata
- RxNorm 1998841One source FDA
- Wikidata Q27279888lotilanerConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C170132LotilanerOne source FDA
- DrugBank DB17992One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000711088 | lotilaner | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | HEH4938D7K | LOTILANER | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1998841 | — | One source FDA |
| Wikidata | Q27279888 | lotilaner | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C170132 | Lotilaner | One source FDA |
| DrugBank | DB17992 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.