Atrioventricular Block clinical trials
The registry lists 117 studies for Atrioventricular Block across more than 10 countries. 43 are recruiting or about to start. 57 of them are mainly about Atrioventricular Block (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
Abbott Medical Devices (7) · Medtronic Cardiac Rhythm and Heart Failure (7) · Boston Scientific Corporation (4) · BackBeat Medical Inc (4) · Biotronik, Inc. (3) · Fu Wai Hospital, Beijing, China (2) · Aalborg University Hospital (2) · Cairdac SA (2)
What is being tested here
Drugs under test in Atrioventricular Block studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexamethasone | 0 | 1 | 1 |
| Immunoglobulins, Intravenous | 0 | 1 | 1 |
| Immunoglobulin G | 0 | 1 | 1 |
| Adenosine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Danish Randomized Trial on Leadless vs Transvenous Pacing · University of Aarhus
- Nov 2026PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial · Yonsei University
- Dec 2026Left Septal Pacing or Left Bundle Branch Pacing to Avoid Left Ventricle Systolic Dysfunction · Parc de Salut Mar
- Dec 2026The Leadless AV Versus DDD Pacing Study · Insel Gruppe AG, University Hospital Bern
- Dec 2026Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry · Rush University Medical Center
- Jan 2027Left Septal or Deep Septal Pacing to Prevent Pacing-induced Cardiomyopathy · Institut d'Investigació Biomèdica de Bellvitge
- Feb 2027Remote ECG Monitoring Post TAVI · Medical University of Silesia
- Mar 2027ALPs Single ChambEr New Device Study · Cairdac SA
- Mar 2027ALPs Single ChambEr New Device · Cairdac SA
- Mar 2027BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System · Biotronik, Inc.
Who these studies take
Of the 29 Atrioventricular Block studies recruiting now, 21 (72%) set no upper age limit and 4 (14%) stop at 75 or younger. 1 (3%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (3%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (3%) | 1 (3%) |
| 18 | 27 (93%) | 27 (93%) |
| 30 | 27 (93%) | 27 (93%) |
| 40 | 27 (93%) | 27 (93%) |
| 50 | 27 (93%) | 27 (93%) |
| 65 | 26 (90%) | 26 (90%) |
| 75 | 26 (90%) | 26 (90%) |
| 85 | 24 (83%) | 24 (83%) |
Across all 117 studies, recruiting or not: 6% stop at 75 or younger and 4% at 65; 12% take children; 1% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Atrioventricular Block studies take
Of 44 interventional studies with no phase under Atrioventricular Block, half reached primary completion within 33 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 33 mo18–55 · 44 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- Transjugular Approach for Implantation of Active Fixation Leadless PacemakersNov 10, 2026NCT07802119
- Novel Approach to Conduction System Pacing With Use of UltrasoundOct 19, 2026NCT06815783
Newly registered2
- Leadless Versus Conventional Pacemakers: Effects on Heart Function and Heart FailureNov 10, 2026NCT07929467
- Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in JapanOct 13, 2026NCT07870837
Studies
Recruiting first, then most recently updated. Showing 50 of 117. Browse all 117 → or search them.
- Transjugular Approach for Implantation of Active Fixation Leadless PacemakersRecruitingNCT07802119Not applicable1 country
- Leadless Versus Conventional Pacemakers: Effects on Heart Function and Heart FailureNot yet recruitingNCT07929467Not applicable1 country
- SPIKE FLOW Endocardial Lead Safety and Performance StudyRecruitingNCT07820072Not applicable1 country
- Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in JapanNot yet recruitingNCT07870837Not applicable1 country
- Novel Approach to Conduction System Pacing With Use of UltrasoundRecruitingNCT06815783Not applicable1 country
- BIOTRONIK Investigation of the LivIQ Leadless Pacemaker SystemRecruitingNCT07118358Not applicable8 countries
- The Impact of LBBAP vs RVP on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular BlockRecruitingNCT06023784Not applicable1 country
- Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal CaptureNot yet recruitingNCT07804394Not applicable
- OPTImizing Lead Placement in Patients Requiring Pacemaker After Cardiac SurgeryNot yet recruitingNCT07795541Not applicable
- BIO|STREAM.CSP CLSRecruitingNCT076088225 countries
- Comparison of Focal Cryoablation vs. Radiofrequency Cardioneuroablation for BradyarrhythmiasRecruitingNCT07671898Not applicable1 country
- Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following TAVRRecruitingNCT041396161 country
- RandomIsed sTudy of Physiologic cArdiac stimuLation in patIents With Atrio-ventricular Conduction DiseaseRecruitingNCT07279870Not applicable1 country
- Aveir DR Real-World Evidence Post-Approval StudyRecruitingNCT059350071 country
- Trial Evaluating the Benefit of Left Bundle Branch Area Stimulation Compared With Conventional Pacing in Post-TAVI Atrioventricular Atrioventricular BlockRecruitingNCT07236489Not applicable1 country
- Remote ECG Monitoring Post TAVIRecruitingNCT07521800Not applicable2 countries
- Randomized Study of Physiological vs Right Ventricular Pacing in Patients With Normal Ventricular Function Post TAVIRecruitingNCT06197503Not applicable1 country
- ALPs Single ChambEr New Device StudyNot yet recruitingNCT07469579Not applicable
- Left Bundle Branch Pacing vs Right Ventricular Pacing on AHRE Burden in Patients With Preserved LVEFRecruitingNCT07250529Not applicable1 country
- ALPs Single ChambEr New DeviceNot yet recruitingNCT07461935Not applicable
- Central Haemodynamics and Pacing for AV BlockRecruitingNCT07276490Not applicable1 country
- Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECGNot yet recruitingNCT07348991
- LLL vs. SDL for LBBP: A Non-inferiority RCTNot yet recruitingNCT07378124Not applicable1 country
- Efficacy and Safety of Micra AV2 Transcatheter Pacing SystemRecruitingNCT07356505Not applicable1 country
- Taiwan Registry for Leadless PacemakerEnrolling by invitationNCT049267921 country
- PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled TrialRecruitingNCT05585411Not applicable1 country
- PACE-AF: Prospective Analysis of Cardiac Electrostimulation and Atrial FibrillationNot yet recruitingNCT072792071 country
- Left vs Left Randomized Clinical TrialRecruitingNCT05650658Not applicable2 countries
- Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD RegistryRecruitingNCT061662771 country
- Physiologic Cardiac Pacing to Prevent Left Ventricular Dysfunction Post TAVIRecruitingNCT05966675Not applicable1 country
- Synchrony in Cardiac Conduction: Assessing the Effects of Pacing on Cardiac Performance Through Magnetic Resonance Imaging and Advanced ECG-imagingNot yet recruitingNCT06843135Not applicable
- Left Septal Pacing or Left Bundle Branch Pacing to Avoid Left Ventricle Systolic DysfunctionRecruitingNCT06707662Not applicable1 country
- AVEIR™ Leadless Pacemaker Registry in Europe and MIddle East Region (PREMIER LEADLESS)Not yet recruitingNCT06782152
- Evaluating the Safety and Effectiveness of 5G Cloud Follow-up for Cardiovascular Implantable Electronic DevicesRecruitingNCT06652750Not applicable1 country
- Efficacy and Safety of Left Bundle Area Pacing Vs Right Ventricular Apical Pacing in Patients with Atrioventricular BlockNot yet recruitingNCT066749671 country
- Factors Affecting Selection of Leadless Pacemaker and Atrioventricular Synchronous Pacing StatusNot yet recruitingNCT065876721 country
- Left Septal or Deep Septal Pacing to Prevent Pacing-induced CardiomyopathyRecruitingNCT06474819Not applicable1 country
- LVSP vs RVP in Patients With AV Conduction DisordersRecruitingNCT04595487Not applicable7 countries
- ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System PacingRecruitingNCT063246821 country
- Pacemaker Implantation Versus Cardioneuroablation for Functional Atrioventricular BlockRecruitingNCT05774262Not applicable1 country
- LEft Bundle branchArea Pacing to Avoid Pacing-induced CARdiomyopathyRecruitingNCT05910866Not applicable1 country
- Outcomes and Safety of Various Conduction System Pacing MethodsRecruitingNCT047498361 country
- Screening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker ImplantationRecruitingNCT056990441 country
- The CT-verified Data Collection Study to Investigate the Correlation Between the Leadless Pacemaker Tip Location and Echo, ECGCompletedNCT069100591 country
- Biventricular Alternative PacingWithdrawnNCT00559143Phase 41 country
- Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-upActive, not recruitingNCT072098527 countries
- AVEIR DR Coverage With Evidence Development (CED) StudyActive, not recruitingNCT059326021 country
- Conduction System Pacing to Prevent Pacing-Induced CardiomyopathyCompletedNCT07831655Not applicable1 country
- Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)Active, not recruitingNCT04474223Phase 32 countries
- Left Bundle Branch Area Pacing Versus Right Ventricular Pacing in Atrioventricular Block With Preserved Ejection FractionActive, not recruitingNCT07464041Not applicable1 country