Medtronic: Atrial Fibrillation trials

The registry lists 80 Atrial Fibrillation studies with Medtronic as lead sponsor. 8 are open to participants now and 38 have results posted.

Phase 1 1Phase 3 4Phase 4 11No phase 64(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Sphere-9 PAF China StudyNot yet recruitingNCT07789925Not applicable
• Outcomes of an Optimized Workflow With PulseSelect Pulsed Field Ablation (PFA) System in Paroxysmal and Persistent Atrial FibrillationNot yet recruitingNCT07575828Not applicable
• Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)RecruitingNCT07298473Not applicable
• PULSED AF Post-Approval StudyRecruitingNCT06578104
• PulseSelect™ PFA Global RegistryRecruitingNCT06393920
• Safety and Performance of the SpherePVI™ Catheter to Treat Paroxysmal Atrial FibrillationRecruitingNCT05144503Not applicable
• Safety and Performance of the Affera SpherePVI™ Multi-Ablation System to Treat Paroxysmal Atrial FibrillationRecruitingNCT05115214Not applicable
• Medtronic Terminate AF StudyRecruitingNCT03546374Not applicable
• Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation SystemCompletedNCT05120193Not applicableResults posted
• DEFINE AFib (Atrial Fibrillation)TerminatedNCT04926857Results posted
• Assessment of the Sphere-9™ Catheter and Affera Mapping and Ablation System for Treatment of Atrial and Ventricular ArrhythmiasCompletedNCT04211441Not applicableResults posted
• An Initial Assessment of the Sphere-9™ Catheter and Affera Mapping and Ablation SystemCompletedNCT04210622Results posted
• Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AFCompletedNCT04198701Not applicableResults posted
• DiamondTemp™ System for the Treatment of Persistent Atrial FibrillationCompletedNCT03643224Not applicableResults posted
• ArcticLine Feasibility StudyCompletedNCT03604263Not applicableResults posted
• DiamondTemp™ Ablation System for the Treatment of Paroxysmal Atrial FibrillationCompletedNCT03334630Not applicableResults posted
• FIRE AND ICE Re-Ablations (Retrospective Data Collection)CompletedNCT03314753Results posted
• AF Septal Pacing (Clinical Investigation Plan)CompletedNCT03242941Not applicableResults posted
• STOP AF First: Cryoballoon Catheter Ablation in an Antiarrhythmic Drug Naive Paroxysmal Atrial FibrillationCompletedNCT03118518Not applicableResults posted
• STOP Persistent AFCompletedNCT03012841Not applicableResults posted
• Spanish Registry of Cryoballoon AblationCompletedNCT02785991Results posted
• Rate of Atrial Fibrillation Through 12 Months in Patients With Recent Ischemic Stroke of Presumed Known OriginCompletedNCT02700945Not applicableResults posted
• Postmarket Evaluation of the Phased Radio Frequency Ablation System (GOLD AF Registry)CompletedNCT02433613Results posted
• Cardiac Resynchronization Therapy Efficacy EnhancementsCompletedNCT02222818Not applicableResults posted
• Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial FibrillationCompletedNCT02064764Not applicableResults posted
• Usability Study to Assess the Reveal LINQ Insertable Cardiac Monitor SystemCompletedNCT01965899Not applicableResults posted
• REVEAL AF: Incidence of AF in High Risk PatientsCompletedNCT01727297Not applicableResults posted
• Evaluation of the Phased Radio Frequency Ablation SystemTerminatedNCT01693120Not applicableResults posted
• Evaluation of the Cardioblate CryoFlex Surgical Ablation System in Longstanding Persistent Atrial FibrillationTerminatedNCT01558635Not applicableResults posted
• Evaluation of the Incidence of Cerebral Lesions Post Pulmonary Vein Ablation Catheter (PVAC)CompletedNCT01520532Not applicableResults posted
• Diagnostic Device Risk Management of Atrial Fibrillation and Heart FailureCompletedNCT01486316Not applicableResults posted
• Sustained Treatment of Paroxysmal Atrial Fibrillation Post-Approval Study (STOP AF PAS)CompletedNCT01456949Not applicableResults posted
• Continued Access ProtocolCompletedNCT00889681Not applicableResults posted
• Ablation of the Pulmonary Veins for Paroxysmal AfibCompletedNCT00744874Phase 4Results posted
• Surgical or Catheter Ablation of Lone Atrial Fibrillation (AF) PatientsTerminatedNCT00703157Not applicableResults posted
• A Clinical Study of the Arctic Front Cryoablation Balloon for the Treatment of Paroxysmal Atrial FibrillationCompletedNCT00523978Phase 3Results posted
• Tailored Treatment of Permanent Atrial FibrillationCompletedNCT00514735Phase 3Results posted
• Medtronic Concomitant Utilization of Radio Frequency for Atrial Fibrillation CURE-AF/PersistentCompletedNCT00506493Phase 3Results posted
• DISCOVERY: Diagnostic Data and Genetic Polymorphisms in ICD Patients.CompletedNCT00478933Not applicableResults posted
• Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) StudyCompletedNCT00431834Phase 3Results posted
• CONNECT Study - Clinical Evaluation Of Remote NotificatioN to rEduCe Time to Clinical DecisionCompletedNCT00402246Not applicableResults posted
• Reducing Episodes by Septal Pacing Efficacy Confirmation Trial (RESPECT)CompletedNCT00289289Not applicableResults posted
• MINERVA: MINimizE Right Ventricular Pacing to Prevent Atrial Fibrillation and Heart FailureCompletedNCT00262119Phase 4Results posted
• Heart Rate Regularization in Patients With Permanent Atrial Fibrillation Post Marketing StudyCompletedNCT00246805Phase 4Results posted
• Electrophysiologically Guided PAcing Site Selection StudyCompletedNCT00239226Phase 4Results posted
• DATAS: The Dual Chamber & Atrial Tachyarrhythmias Adverse Events StudyCompletedNCT00157820Not applicableResults posted
• Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)Active, not recruitingNCT07308847Not applicable
• The CT-verified Data Collection Study to Investigate the Correlation Between the Leadless Pacemaker Tip Location and Echo, ECGActive, not recruitingNCT06910059
• SPHERE Per-AF Post-Approval StudyActive, not recruitingNCT06858306
• Affera Global RegistryActive, not recruitingNCT06026345
• DIAMOND AF Post-Approval StudyTerminatedNCT05230524
• STOP AF First Post-Approval StudyCompletedNCT05227053
• STOP Persistent AF PASActive, not recruitingNCT05005949
• European CURE-AF StudyCompletedNCT04645615Not applicable
• FIRE AND ICE II Trial PilotCompletedNCT03706677Not applicable
• Evaluation for the Characterization of the Safety Profile of the DiamondTemp™ System for Fast Treatment of Patients With Atrial FibrillationCompletedNCT03626649Not applicable
• ACT DiamondTemp TempeRAture-Controlled and Contact Sensing RF Ablation Clinical Trial for Atrial FibrillationCompletedNCT02821351Not applicable
• Cryo Global RegistryCompletedNCT02752737
• Spinal Cord Stimulation to Treat Post-operative Atrial FibrillationTerminatedNCT02530203Not applicable
• Cryoballoon Ablation for Early Persistent Atrial Fibrillation (Cryo4 Persistent AF)CompletedNCT02213731Not applicable
• Catheter Cryoablation Versus Antiarrhythmic Drug as First-Line Therapy of Paroxysmal Atrial FibrillationCompletedNCT01803438Phase 4
• PRECISION GOLD Post Market Study in Europe of Pulmonary Vein Ablation Catheter (PVAC GOLD)CompletedNCT01767558Not applicable
• Durability of Pulmonary Vein Isolation Following Cryoablation for Treatment of Paroxysmal Atrial FibrillationCompletedNCT01645917Phase 4
• AV-node Stimulation Clinical Download Study to Reduce Ventricular Rate During AFCompletedNCT01095952Not applicable
• PAF-HEFT (Permanent Atrial Fibrillation in Heart Failure Trial)TerminatedNCT00839566Phase 4
• Atrial Fibrillation Ablation Pilot StudyCompletedNCT00744835Phase 1
• Reveal® XT Performance Trial (XPECT)CompletedNCT00680927Phase 4
• INSIGHT (R)XT. Indications for Diagnosis, Arrhythmia and Monitoring of Reveal XTCompletedNCT00680550
• Medtronic Genetic Arrhythmia Markers for Early Detection (GAME Study)CompletedNCT00664807
• The Atrial High Rate Episodes in Pacemaker PatientsCompletedNCT00627328
• PANORAMA Observational StudyCompletedNCT00382525
• SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular ConductionCompletedNCT00284830Not applicable
• TRENDS: A Prospective Study of the Clinical Significance of Atrial Arrhythmias Detected by Implanted Device DiagnosticsCompletedNCT00279981
• Clinical Investigation of the Medtronic Concerto™ DeviceCompletedNCT00268320Not applicable
• Restoring Sinus Rhythm With Cardiac Resynchronization in Patients With Atrial Fibrillation (ReSync AF)CompletedNCT00268294Not applicable
• Study for Atrial Fibrillation Reduction (SAFARI)CompletedNCT00267137Not applicable
• CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atrial FibrillationTerminatedNCT00170313Phase 4
• Clinical and Economic Consequences of Left Atrial Bipolar Radiofrequency Ablation of Persistent and Permanent Atrial Fibrillation During Cardiac SurgeryTerminatedNCT00157807Not applicable
• LEAF - Low Energy In Atrial FibrillationCompletedNCT00157781Phase 4
• Study to Characterize Atrial Fibrillation in CHF Patients Indicated for CRTCompletedNCT00156728Phase 4