Clinical trials in Sierra Leone
57 studies list at least one site in Sierra Leone. 8 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-22.
Status
- Completed
- 39
- Recruiting
- 6
- Active, not recruiting
- 6
- Not yet recruiting
- 2
- Terminated
- 2
- Status unknown
- 1
Phase
- Phase 2
- 8
- Phase 3
- 6
- Phase 4
- 3
- Phase 1
- 1
Most studied here
Who runs them
Washington University School of Medicine (9) · Boston College (7) · London School of Hygiene and Tropical Medicine (5) · Doctors with Africa - CUAMM (4) · Barcelona Institute for Global Health (2) · University of Michigan (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Janssen Vaccines & Prevention B.V. (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 57 — search for more.
- ICU-related Out of Pocket Expenses (ICOPE)RecruitingNCT07439692
- Study Assessing Reduced HPV Infectivity and Transmission in HPV-Positive Women Following Vaccination With 9vHPVNot yet recruitingNCT07303751Phase 2
- EBOla Post-Exposure ProphylaxisNot yet recruitingNCT06841614Phase 3
- Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute MalnutritionRecruitingNCT06869850Not applicable
- Reducing Mortality in Adults With Advanced HIV Disease (REVIVE)RecruitingNCT05580666Phase 3
- Global Burden Estimation of Human Papillomavirus (GLOBE-HPV)RecruitingNCT06129253
- Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled TrialRecruitingNCT05899140Phase 4
- Pulmonary Edema Resolution in Severe Preeclampsia and EclampsiaRecruitingNCT06219109
- Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study)CompletedNCT02156102
- Advancing mHealth-supported Adoption and Sustainment of an Evidence-based Mental Health Intervention in Sierra LeoneActive, not recruitingNCT05737667Not applicable
- SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial DisabilitiesCompletedNCT06007105Not applicable
- REVIVE (Response to the Ebola Virus Vaccine)Active, not recruitingNCT05992480Phase 4
- Improving Care Through Azithromycin Research for Infants in AfricaActive, not recruitingNCT04235816Phase 3
- Improving Cognition and Gestational Duration With Targeted NutritionActive, not recruitingNCT05949190Not applicable
- MULTIple Doses of IPTi Proposal: a Lifesaving High Yield InterventionCompletedNCT05085340
- Seeing to Learn in Sierra LeoneTerminatedNCT06065631Not applicable
- Deploying Emergency Bystander Internet TrainingCompletedNCT05909917Not applicable
- Kinshasa Lung Ultrasound Approach ValidationCompletedNCT06839963
- Intergenerational Study of War-Affected YouthActive, not recruitingNCT06440460
- Project My Heart Your Heart: Pacemaker ReuseActive, not recruitingNCT04016870Not applicable
- A Study of 2-dose Vaccination Regimen of Ad26.ZEBOV and MVA-BN-Filo in InfantsCompletedNCT03929757Phase 2
- Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone StudyCompletedNCT05284097Phase 2
- Evaluation of a Family Strengthening Program Evaluation in Sierra Leone to Prevent Family SeparationCompletedNCT05632237Not applicable
- Impact of an Innovative Childhood TB Diagnostic Approach Decentralized to District Hospital and Primary Health Care Levels on Childhood Tuberculosis Case Detection and Management in High Tuberculosis Incidence Countries (TB-Speed Decentralisation)CompletedNCT04038632Not applicable
- Eggs for Gut HealthCompletedNCT06002438Not applicable
- Partnership for Research on Ebola VACcinationsCompletedNCT02876328Phase 2
- Milk Matters in Malnutrition, is it the Lactose or Dairy Protein?CompletedNCT04216043Not applicable
- Ad26.ZEBOV Booster in Children Previously Vaccinated With Ad26.ZEBOV and MVA-BN-Filo (EBOVAC Booster Study)CompletedNCT04711356Phase 2
- Mobile Health (mHealth) Tools to Improve Delivery Quality of a Family Home Visiting InterventionCompletedNCT04481399Not applicable
- Youth FORWARD Phase 2 YRI and EPP StudyCompletedNCT03542500Not applicable
- EBOVAC-Salone ExtensionCompletedNCT03820739
- Effect of an Alternative RUTF on Intestinal Permeability in Children With Severe Acute MalnutritionCompletedNCT04334538Not applicable
- Staged Phase 3 Study to Assess the Safety and Immunogenicity of Ebola Candidate Vaccines Ad26.ZEBOV and MVA-BN-FiloCompletedNCT02509494Phase 3
- Cardiovascular Function and Ribavirin Pharmacokinetics and Pharmacodynamics in Patients With Lassa FeverTerminatedNCT03889106
- Africa COVID-19 Vaccine HesitancyCompletedNCT04912284
- Nutritional and Anti-infective Interventions for Malnutrition in Pregnancy (Beleuman Welbodi)CompletedNCT03079388Not applicable
- Treatment of High-Risk Moderate Acute Malnutrition Using Expanded Admission CriteriaCompletedNCT03647150Not applicable
- Moderate Acute Malnutrition (MAM) and Severe Acute Malnutrition (SAM) in Sierra LeoneCompletedNCT01785680Not applicable
- Contagious Misinformation TrialCompletedNCT04112680Not applicable
- Comparison of an Alternative Therapeutic Food for the International Food Aid Market to a Standard Ready-to-use Therapeutic Food (RUTF) for the Treatment of Severe Acute Malnutrition in ChildrenCompletedNCT03407326Not applicable
- Critically-Ill Women Admitted to an Obstetric High Dependency Unit in a Resource-Limited SettingCompletedNCT04121234
- Reliability of Simple Sonographic Findings Acquired With Hand-held Apparatuses to Inform Obstetric DiagnosisCompletedNCT03856307
- Putative Investigational Therapeutics in the Treatment of Patients With Known Ebola InfectionCompletedNCT02363322Phase 1/2
- Youth FORWARD Phase 1 YRI and EPP StudyCompletedNCT03603613Not applicable
- Maternal Cesarian Section Infection (MACSI) in Sierra LeoneStatus unknownNCT03929991
- Sub-Trial of the Youth Readiness Intervention (YRI): Treatment of Control Group and Addition of Stress BiomarkersWithdrawnNCT02128568Not applicable
- Lung Ultrasound to Detect Pulmonary Complications in Critically Ill ParturientsCompletedNCT03828630
- Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute MalnutritionCompletedNCT03146897Not applicable
- Trial of the Youth Readiness InterventionCompletedNCT01684488Not applicable
- Adapting Mental Health Interventions for War-Affected Youth Through Employment ProgramsCompletedNCT02561949Not applicable