Lung Diseases, Interstitial clinical trials
The registry lists 680 studies for Lung Diseases, Interstitial across more than 10 countries. 246 are recruiting or about to start. 333 of them are mainly about Lung Diseases, Interstitial (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 9 narrower conditions too, such as Idiopathic Pulmonary Fibrosis: 1,658 studies, 460 open.
ClinicalTrials.gov finds 1,776 studies for Lung Diseases, Interstitial. How that becomes 679 here
This page counts the studies the registry files under Lung Diseases, Interstitial, and those it files under no condition that list Lung Diseases, Interstitialthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,776Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −962Filed under a narrower condition, counted on its own pageIdiopathic Pulmonary Fibrosis 469 · Pulmonary Fibrosis 183 · Granulomatosis with Polyangiitis 102 · Histiocytosis, Langerhans-Cell 80 · Sarcoidosis, Pulmonary 54 · Radiation Pneumonitis 35 · 3 more
- −16List Lung Diseases, Interstitial as a condition, but the registry did not file them under itMost often written as “Diffuse Interstitial Lung Disease” (2), “Interstitial Lung Disease Due to Systemic Disease” (2), and “Pneumonia, Interstitial Plasma Cell” (1). The registry filed them under other conditions only, most often Lung Diseases (3) and Pulmonary Arterial Hypertension (3).
- −121Match it another way49 name it in the title, 2 in a keyword, and 70 by a synonym or other text the search reads.
- 677Counted here and found by its search38 of them list Lung Diseases, Interstitial in their own words; the registry filed them under no condition.
- +2
Counted here, but its search does not find them
- 679The count on this page
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Status
Who runs them
Boehringer Ingelheim (24) · Assiut University (18) · Assistance Publique - Hôpitaux de Paris (12) · United Therapeutics (8) · Post Graduate Institute of Medical Education and Research, Chandigarh (8) · Duke University (7) · Mayo Clinic (7) · Celgene (7)
What is being tested here
Drugs under test in Lung Diseases, Interstitial studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Nerandomilast | 4 | 4 | 6 |
| Belimumab | 4 | 3 | 4 |
| Treprostinil | 3 | 7 | 10 |
| Treprostinil hexadecyl ester | 3 | 4 | 5 |
| Mosliciguat | 2 | 1 | 3 |
| Dexamethasone | 2 | 1 | 3 |
| Hydroxychloroquine | 2 | 0 | 3 |
| CBP-8 gallium GA-68 | 2 | 0 | 2 |
| Pirfenidone | 1 | 0 | 10 |
| Nintedanib | 1 | 7 | 10 |
Drug classes tested here Corticosteroids 4 open · Tyrosine kinase inhibitors (TKIs) 2 open · JAK inhibitors 2 open · Alkylating agents 1 open · Endothelin receptor antagonists 7
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jan 2027Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) · Phase 3 · AstraZeneca
- Apr 2027Efficacy and Safety of Olokizumab in Patients With Progressive Fibrosing Interstitial Lung Diseases · Phase 3 · R-Pharm International, LLC
- Apr 2027A Study to Test Whether Nerandomilast Helps People With Lung Fibrosis Related to Rheumatic Diseases · Phase 3 · Boehringer Ingelheim
- May 2027A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Qifangfeixian Granules in the Treatment of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD) · Phase 3 · Huilan Zhang
- Nov 2027Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF) · Phase 3 · United Therapeutics
- Nov 2026Platform Clinical Study for Conquering Scleroderma · Scleroderma Research Foundation, Inc.
- Nov 2026dEtection of rheumAtoid aRthritis - Interstitial Lung dIseasE by Thoracic ultRasound · University Hospital, Tours
- Dec 2026Prednisolone for 12 Versus 6 Months to Treat Pulmonary Sarcoidosis · Post Graduate Institute of Medical Education and Research, Chandigarh
- Dec 2026CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia · University Hospital, Tours
- Dec 2026Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease · Centre hospitalier de l'Université de Montréal (CHUM)
Who these studies take
Of the 174 Lung Diseases, Interstitial studies recruiting now, 109 (63%) set no upper age limit and 26 (15%) stop at 75 or younger. 13 (7%) take children under 18. 0 (0%) are for women only and 1 (1%) for men only; 22 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 12 (7%) | 12 (7%) |
| 18 | 149 (86%) | 149 (86%) |
| 30 | 154 (89%) | 154 (89%) |
| 40 | 169 (97%) | 169 (97%) |
| 50 | 170 (98%) | 171 (98%) |
| 65 | 166 (95%) | 167 (96%) |
| 75 | 162 (93%) | 163 (94%) |
| 85 | 130 (75%) | 131 (75%) |
Across all 680 studies, recruiting or not: 16% stop at 75 or younger and 5% at 65; 10% take children; <1% are for women only and 1% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lung Diseases, Interstitial studies take
Of 53 phase 2 interventional studies under Lung Diseases, Interstitial, half reached primary completion within 48 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 48 mo30–71 · 53 studies | — | — |
| Phase 3 | 33 mo29–61 · 36 studies | — | — |
| Interventional, no phase | 27 mo14–44 · 118 studies | — | 27 mo14–46 · 114 studies |
| Observational | 55 mo31–83 · 132 studies | — | 72 mo35–274 · 111 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- A Study to Assess the Efficacy and Safety of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Progressive Pulmonary Fibrosis (PPF)Nov 2, 2026NCT07805785
- Study of the Prevalence of Acid Sphingomyelinase Deficiency/Niemann Pick AB and B Disease in Patients With Diffuse Interstitial Lung DiseaseOct 15, 2026NCT06869499
Results posted2
- Multinational Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary FibrosisOct 15, 2026NCT05255991
- Myositis Interstitial Lung Disease Nintedanib TrialOct 15, 2026NCT05799755
Stopped1
- Sjogren's Lung StudyTerminatedNov 9, 2026NCT04843345
Newly registered3
- Chronic Respiratory Disease Participant Engagement StudyNov 9, 2026NCT07924462
- TBLC vs NIVATS in Interstitial Lung DiseaseNov 2, 2026NCT07910448
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesOct 14, 2026NCT07873931
Studies
Recruiting first, then most recently updated. Showing 50 of 680. Browse all 680 → or search them.
- A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)RecruitingNCT07366034Phase 322 countries
- An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)RecruitingNCT07234032Phase 38 countries
- Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With Idiopathic Pulmonary FibrosisRecruitingNCT07284459Phase 219 countries
- CT Quantitative Assessment of Interstitial Lung DiseaseNot yet recruitingNCT059474221 country
- Senicapoc in Patients With Worsening Fibrotic Interstitial Lung DiseaseRecruitingNCT06714123Phase 23 countries
- Chronic Respiratory Disease Participant Engagement StudyRecruitingNCT079244621 country
- Inspiratory Muscle Training in Lung Transplant CandidatesRecruitingNCT06370832Not applicable1 country
- Ambulatory Oxygen Therapy for Individuals With Mild-to-moderate Interstitial Lung DiseaseRecruitingNCT06053164Phase 21 country
- A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary FibrosisRecruitingNCT06968845Phase 27 countries
- Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary HypertensionRecruitingNCT06911632Not applicable1 country
- A Study to Assess the Efficacy and Safety of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Progressive Pulmonary Fibrosis (PPF)RecruitingNCT07805785Phase 31 country
- TBLC vs NIVATS in Interstitial Lung DiseaseNot yet recruitingNCT07910448Not applicable1 country
- Investigating Novel Strategies in Pediatric Immune Responses and Microbiome Environment: Comprehensive Lung Disease Investigation in Children.Enrolling by invitationNCT067460771 country
- FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease ProgressionRecruitingNCT07540988Phase 320 countries
- A Clinical Trial of NS-863 in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)RecruitingNCT07441278Phase 22 countries
- A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary FibrosisRecruitingNCT07201922Phase 313 countries
- Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung DiseaseRecruitingNCT07473700Phase 26 countries
- Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT ImagingRecruitingNCT07613099Phase 31 country
- Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)RecruitingNCT07179380Phase 330 countries
- Optimizing the Diagnostic Journey in Interstitial Lung Disease: The OPTIMIZE-ILD-1 TrialRecruitingNCT07482917Not applicable1 country
- Premedication With Dexamethasone for Preventing Interstitial Lung Disease in Patients With Breast Cancer Treated With Trastuzumab DeruxtecanNot yet recruitingNCT07828054Phase 3
- Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung DiseaseEnrolling by invitationNCT04905693Phase 318 countries
- An Expanded Access Study to Assess Treprostinil Palmitil Inhalation Powder (TPIP) for Participants With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)AvailableNCT06939647
- RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic SclerosisRecruitingNCT06328777Phase 2/31 country
- LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)RecruitingNCT05798923Phase 21 country
- Study of the Prevalence of Acid Sphingomyelinase Deficiency/Niemann Pick AB and B Disease in Patients With Diffuse Interstitial Lung DiseaseRecruitingNCT06869499Not applicable1 country
- A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILDRecruitingNCT07285655Phase 312 countries
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesNot yet recruitingNCT07873931Phase 16 countries
- Nebulized Human Amniotic Fluid in Patients With Interstitial Lung DiseaseRecruitingNCT07372989Phase 11 country
- CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis PneumoniaRecruitingNCT06892951Phase 1/21 country
- Effects of Inspiratory Muscle Training and Positive Expiratory Pressure on Mechanically Ventilated Restrictive Lung Disease PatientsRecruitingNCT07867730Not applicable1 country
- Remote Evaluation and Surveillance of Patients With Interstitial Lung Disease: Transforming ILD Care Delivery With Remote MonitoringRecruitingNCT07673237Not applicable1 country
- A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)RecruitingNCT07175038Phase 29 countries
- Gabapentin vs. Benzonatate vs. Standard of Care for Cough in ILDNot yet recruitingNCT07859839Phase 41 country
- Study of Hospitalised Patients With Acute Respiratory ConditionsRecruitingNCT050950901 country
- Home-based Pulmonary Rehabilitation in Interstitial Lung DiseaseRecruitingNCT07830602Not applicable1 country
- Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung DiseaseRecruitingNCT05785065Phase 21 country
- Clinical Efficacy of Telitacicept in Sjögren's Disease With Interstitial Lung DiseaseRecruitingNCT078433811 country
- Artificial Intelligence Enhanced Remote Monitoring in Interstitial Lung DiseaseNot yet recruitingNCT07844915Not applicable1 country
- Combined Growth Differentiation Factor-15 (GDF-15) and Lung Ultrasound for ILD Screening in Rheumatoid Arthritis and Systemic SclerosisNot yet recruitingNCT07839221
- Tele-Pulmonary Rehabilitation For Patients With Chronic Lung DiseasesRecruitingNCT07666841Not applicable1 country
- A Randomized, Double-Blind, Placebo-Controlled Trial of Fufei Huazhuo Tongluo Formula Combined With Standardized Medicine in Patients With Anti-Synthetase Syndrome-Associated Interstitial Lung DiseaseNot yet recruitingNCT07836790Not applicable1 country
- Validation of 1 Minute Sit-to Stand Test for Assessment of Breathlessness at Exertion in Individuals With Chronic Lung DiseaseNot yet recruitingNCT078367641 country
- Evaluation of the Reproducibility of the Automated Measurement of the Extent of ILD on Chest CTRecruitingNCT06743022Not applicable1 country
- Risk Factors of Venous Thrombotic Event in Interstitial Lung DiseaseNot yet recruitingNCT07833254
- Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene VariantsNot yet recruitingNCT07443436Phase 21 country
- Study Evaluating 68GA-FAPI-46 PET/CT in Patients With Interstitial Lung DiseaseNot yet recruitingNCT07817563Phase 11 country
- Global Utilization And Registry Database for Improved preservAtion of doNor LUNGsEnrolling by invitationNCT049302892 countries
- Pulmonary Fibrosis Foundation Community RegistryRecruitingNCT053825721 country
- A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung DiseaseRecruitingNCT07323732Phase 21 country