Postoperative Hemorrhage clinical trials
The registry lists 135 studies for Postoperative Hemorrhage across more than 10 countries. 31 are recruiting or about to start. 62 of them are mainly about Postoperative Hemorrhage (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its narrower condition Endoleak too: 164 studies, 37 open.
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Status
Who runs them
St. Olavs Hospital (4) · Bayer (3) · Egymedicalpedia (3) · CytoSorbents, Inc (3) · Cairo University (3) · Mallinckrodt (2) · University of Liege (2) · Sheba Medical Center (2)
What is being tested here
Drugs under test in Postoperative Hemorrhage studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Tranexamic Acid | 5 | 5 | 25 |
| Dutasteride | 1 | 0 | 1 |
| Calcium Gluconate | 1 | 0 | 1 |
| Protamines | 1 | 0 | 1 |
| Rocuronium | 1 | 0 | 1 |
| Fibrinogen | 0 | 0 | 3 |
| Ketorolac | 0 | 0 | 2 |
| Oxytocin | 0 | 0 | 2 |
| Bupivacaine | 0 | 0 | 2 |
| Deamino Arginine Vasopressin | 0 | 0 | 2 |
Drug classes tested here NSAIDs 5 · Local anesthetics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 9
- Nov 2026Ultrasound for Assessment of Intra-Abdominal Blood Loss After Gynecological Surgery · Holy Family Hospital, Nazareth, Israel
- Jan 2027EFFICACY OF INTRAOPERATIVE ARISTA POLYSACCHARIDE APPLICATION ON THE POSTOPERATIVE BLOOD LOSS IN PATIENTS UNDERGOING RARP FOR THE TREATMENT OF PROSTATE CANCER · St. Antonius Hospital Gronau
- Feb 2027Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL · Benha University
- Feb 2027Flow-Based Platelet Function Assessment Using Total Thrombus-Formation Analysis System (T-TAS) and Early Bleeding After Cardiac Surgery With Cardiopulmonary Bypass (CPB) · Hospital de la Santa creu i Sant Pau - Barcelona
- Apr 2027Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty · St. Mary's Research Center, Canada
- Apr 2027Perioperative Dutasteride for Hemorrhage Control in Bipolar TURP Under Anticoagulation. · Mohamed Mahmoud Dogha
- May 2027Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery. · Hemorai Inc
- Jun 2027Ostene in Thoracolumbar Decompression and Fusion Evaluated With VIBE · University of Maryland, Baltimore
- Aug 2027Tranexamic Acid in Nasal Mohs Reconstruction · Vanderbilt University Medical Center
Who these studies take
Of the 17 Postoperative Hemorrhage studies recruiting now, 11 (65%) set no upper age limit and 4 (24%) stop at 75 or younger. 2 (12%) take children under 18. 3 (18%) are for women only and 2 (12%) for men only; 6 (35%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (6%) | 1 (6%) |
| 18 | 14 (82%) | 12 (71%) |
| 30 | 14 (82%) | 12 (71%) |
| 40 | 14 (82%) | 12 (71%) |
| 50 | 14 (82%) | 13 (76%) |
| 65 | 14 (82%) | 13 (76%) |
| 75 | 13 (76%) | 12 (71%) |
| 85 | 12 (71%) | 11 (65%) |
Across all 135 studies, recruiting or not: 31% stop at 75 or younger and 25% at 65; 16% take children; 16% are for women only and 3% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Postoperative Hemorrhage studies take
Of 13 phase 4 interventional studies under Postoperative Hemorrhage, half reached primary completion within 16 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 4 | 16 mo11–23 · 13 studies | — | — |
| Interventional, no phase | 14 mo8–23 · 38 studies | — | 14 mo10–23 · 35 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Newly registered4
- Prospective, Multicenter, Randomized Controlled Phase III Trial of Biological Mesh for Alimentary Tract Reconstruction in Digestive SurgeryNov 6, 2026NCT07921732
- Systematic Intraoperative Cell Salvage in On-Pump Cardiac Surgery Within a Mature Patient Blood Management ProgrammeNov 6, 2026NCT07922486
- Post-extraction Bleeding in Older Adults on Uninterrupted Antiplatelet TherapyNov 3, 2026NCT07913035
- Perioperative Dutasteride for Hemorrhage Control in Bipolar TURP Under Anticoagulation.Nov 2, 2026NCT07911501
Studies
Recruiting first, then most recently updated. Showing 50 of 135. Browse all 135 → or search them.
- Change in Platelet Lipid Metabolism and Procoagulant Phenotype Induced by Cardiopulmonary Bypass. Impact on Postoperative Inflammatory Response and Bleeding Complications During Cardiac Surgery.RecruitingNCT07630987Not applicable1 country
- Systematic Intraoperative Cell Salvage in On-Pump Cardiac Surgery Within a Mature Patient Blood Management ProgrammeNot yet recruitingNCT079224861 country
- Prospective, Multicenter, Randomized Controlled Phase III Trial of Biological Mesh for Alimentary Tract Reconstruction in Digestive SurgeryRecruitingNCT07921732Not applicable1 country
- Perioperative Dutasteride for Hemorrhage Control in Bipolar TURP Under Anticoagulation.Not yet recruitingNCT07911501Phase 41 country
- Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.Not yet recruitingNCT07826637Not applicable1 country
- Observational Study of Platelet Dysfunction Assessed by Thromboelastography in Cardiovascular Surgery (DISPLATEG)RecruitingNCT069611751 country
- Tranexamic Acid in Nasal Mohs ReconstructionRecruitingNCT06057675Phase 21 country
- Ostene in Thoracolumbar Decompression and Fusion Evaluated With VIBEEnrolling by invitationNCT064508341 country
- TEG Use in Children Undergoing Procedures With High Anticipated Blood LossNot yet recruitingNCT05379530Not applicable
- Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNLNot yet recruitingNCT07749807Not applicable1 country
- Oral Versus Intravenous Tranexamic Acid in Off-Pump Coronary Artery Bypass SurgeryNot yet recruitingNCT07740330Phase 41 country
- Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine AtonyRecruitingNCT07217899Phase 21 country
- Spinal Versus General Anesthesia in Open Simple ProstatectomyRecruitingNCT07643415Not applicable1 country
- Flow-Based Platelet Function Assessment Using Total Thrombus-Formation Analysis System (T-TAS) and Early Bleeding After Cardiac Surgery With Cardiopulmonary Bypass (CPB)Not yet recruitingNCT07619261
- EFFICACY OF INTRAOPERATIVE ARISTA POLYSACCHARIDE APPLICATION ON THE POSTOPERATIVE BLOOD LOSS IN PATIENTS UNDERGOING RARP FOR THE TREATMENT OF PROSTATE CANCERRecruitingNCT06822036Not applicable1 country
- Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and EcchymosisRecruitingNCT05774717Phase 11 country
- Dose for Reversal of Heparin After Cardiopulmonary BypassRecruitingNCT07477977Not applicable1 country
- Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee ArthroplastyRecruitingNCT06208267Not applicable1 country
- Ultrasound for Assessment of Intra-Abdominal Blood Loss After Gynecological SurgeryRecruitingNCT069531411 country
- GENECARD - the Use of Genetic, Epigenetic, Metabolomic, Proteomic and Microbiotic Markers, Image and Voice Biomarker Analyses, and Pre- and Intraoperative Clinical Data - to Predict Early Complications After Cardiac Surgery.Not yet recruitingNCT073454031 country
- Perioperative Risk in Patients on Chronic Aspirin Undergoing CraniotomyNot yet recruitingNCT070861833 countries
- Development and Pilot Evaluation of a Urethral Catheter Traction Device for Post-TURP Hemorrhage ControlRecruitingNCT07287488Not applicable1 country
- Comparative Study of Tranexamic Acid Dosing in Cardiac SurgeryRecruitingNCT07164300Not applicable1 country
- Diet Education and Postoperative Outcomes in Pediatric AdenotonsillectomyNot yet recruitingNCT06988748Not applicable1 country
- The Effect of Local Infiltration of Tranexamic Acid on Postoperative Blood Loss in Orthognathic SurgeryNot yet recruitingNCT06983886Phase 1/21 country
- Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing HysterectomyRecruitingNCT06969326Phase 31 country
- Usability of Pericardial Flushing with the Haermonics Pure System After Cardiac SurgeryNot yet recruitingNCT06521164Not applicable
- Fresh Autologous Whole Blood Transfusion After Cardiopulmonary BypassRecruitingNCT03204357Not applicable1 country
- Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle RelaxantsRecruitingNCT06399445Phase 41 country
- Femoral Blood Gas and Prediction of Postoperative BleedingNot yet recruitingNCT06285656
- Effect of Early Administration of TXA in Adult Hip FracturesRecruitingNCT05047133Phase 2/31 country
- Post-extraction Bleeding in Older Adults on Uninterrupted Antiplatelet TherapyCompletedNCT079130351 country
- Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)CompletedNCT04976530Not applicable2 countries
- Safe and Timely Antithrombotic Removal (STAR) RegistryActive, not recruitingNCT050771246 countries
- Chitosan-Based, Gelatin Sponge and Non-absorbable Nasal Packing After Endoscopic Sinus SurgeryCompletedNCT07862283Not applicable1 country
- Bizact Tonsillectomy: Postoperative Pain, Bleeding and Cost-effectiveness (Randomized Study)CompletedNCT07842419Not applicable1 country
- Effect of Tranexamic Acid on Bleeding After Bariatric SurgeryCompletedNCT077543961 country
- Kaolin-based Hemostatic Gauze in Total Knee ArthroplastyCompletedNCT05504577Phase 41 country
- Tranexamic Acid Versus Misoprostol to Reduce Blood Loss During and After Cesarean SectionCompletedNCT07712510Phase 41 country
- EFFECT OF TRANEXAMIC ACID ON PERIOPERATIVE BLOOD LOSS IN REAMED INTRAMEDULLARY NAILING OF DIAPHYSEAL FEMORAL AND TIBIAL FRACTURES: A PROSPECTIVE COMPARATIVE STUDYCompletedNCT07625709Not applicable1 country
- IV Ketorolac on Platelet Function Post-Cesarean DeliveryCompletedNCT03805607Phase 41 country
- Cyanoacrylate Versus Omentum for Staple-Line Reinforcement in Sleeve GastrectomyCompletedNCT07339020Not applicable1 country
- Hemoglobin Drop and Need for Blood Transfusion in Primary Knee Arthroplasty With or Without Drain InsertionCompletedNCT07494708Not applicable1 country
- Autologous Whole Blood Management for Transfusion Reduction in Adult Cardiac Surgery PatientsCompletedNCT05889494Not applicable1 country
- Warm Saline Irrigation Before Omentopexy to Reduce Early Bleeding After Laparoscopic Sleeve GastrectomyCompletedNCT07475169Not applicable1 country
- Haemorrhoidectomy With vs Without Lateral Internal SphincterotomyCompletedNCT07360912Not applicable1 country
- Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)TerminatedNCT05093504Not applicable1 country
- Developing an Intervention to Improve the Non-Technical Skills of the Cardiac Surgical TeamsWithdrawnNCT06257511Not applicable
- Tranexamic Acid Instillation in Laparoscopic CholecystectomyCompletedNCT06246422Not applicable1 country
- Stratafix Vs. Vicryl OAGB / MGB Suture StudyCompletedNCT04613635Not applicable1 country