Menorrhagia clinical trials
The registry lists 206 studies for Menorrhagia across more than 10 countries. 35 are recruiting or about to start. 119 of them are mainly about Menorrhagia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Who runs them
Bayer (19) · Assiut University (8) · AbbVie (8) · Abbott (7) · Ferring Pharmaceuticals (5) · Minerva Surgical, Inc. (5) · Gynesonics (5) · Myovant Sciences GmbH (5)
What is being tested here
Drugs under test in Menorrhagia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Tranexamic Acid | 2 | 5 | 13 |
| Relugolix | 1 | 5 | 5 |
| Calcium Dobesilate | 1 | 1 | 2 |
| Cyclobenzaprine | 1 | 0 | 1 |
| Ginger extract | 1 | 0 | 1 |
| Ferrosoferric Oxide | 1 | 0 | 1 |
| Elagolix | 0 | 4 | 7 |
| Asoprisnil | 0 | 6 | 7 |
| Levonorgestrel | 0 | 4 | 5 |
| Estradiol | 0 | 3 | 4 |
Drug classes tested here Hormonal contraceptives 16 · NSAIDs 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids · Phase 3 · Qilu Pharmaceutical Co., Ltd.
- Nov 2026Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) · Duke University
- Dec 2026Evaluating the Reliability and Validity of the Arabic Version of the SAMANTA Questionnaire: A Step Toward Improved Diagnosis of Heavy Menstrual Bleeding · Assiut University
- Dec 2026Prevalence and Impact on Quality of Life, Academic Performance, and Blood Indices of Heavy Menstrual Bleeding Among Female Students in Assiut University, Egypt · Assiut University
- Jan 2027Phase II Study of CMS-D002 Capsule for Uterine Fibroids With Menorrhagia · Shenzhen Kangzhe Biotechnology Co., Ltd.
- Jun 2027HIFU Versus Myomectomy for the Treatment of Symptomatic Uterine Fibroids · Chinese University of Hong Kong
- Jun 2027HMBeacon: A Phase 2 Study to Evaluate ALN-6400 in Adult and Adolescent Female Patients With VWD and HMB · Alnylam Pharmaceuticals
- Jul 2027Hormonal Management of Heavy Menstrual Bleeding in Adolescents · University Hospital, Geneva
- Aug 2027Delivering tAN to Reduce HMB: The LUNA Study · Spark Biomedical, Inc.
- Oct 2027Heavy Menstrual Bleeding and Dysmenorrhea Among Undergraduate Females in the Faculty of Medicine of Assiut University · Assiut University
Who these studies take
Of the 23 Menorrhagia studies recruiting now, 4 (17%) set no upper age limit and 19 (83%) stop at 75 or younger. 5 (22%) take children under 18. 22 (96%) are for women only and 0 (0%) for men only; 5 (22%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (13%) | 1 (4%) |
| 18 | 14 (61%) | 1 (4%) |
| 30 | 16 (70%) | 0 (0%) |
| 40 | 19 (83%) | 0 (0%) |
| 50 | 15 (65%) | 0 (0%) |
| 65 | 5 (22%) | 0 (0%) |
| 75 | 4 (17%) | 0 (0%) |
| 85 | 4 (17%) | 0 (0%) |
Across all 206 studies, recruiting or not: 70% stop at 75 or younger and 69% at 65; 15% take children; 95% are for women only and 0% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Menorrhagia studies take
Of 17 phase 3 interventional studies under Menorrhagia, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 27 mo24–35 · 17 studies | — | — |
| Interventional, no phase | 24 mo14–35 · 23 studies | — | — |
| Observational | 61 mo41–102 · 21 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered3
- Clinical Study on the Safety and the Performance of an Endometrial Ablation System in Women With Abnormal Uterine Bleeding (AUB) and Previous Cesarean Delivery.Nov 9, 2026NCT07925008
- Ultrasound-Guided Radiofrequency Ablation for Focal AdenomyosisOct 30, 2026NCT07906535
- A Clinical Study of the Aqua Therapeutics Thermal Therapy Vapor Ablation System in Premenopausal Women With Abnormal Uterine BleedingOct 16, 2026NCT07877051
Studies
Recruiting first, then most recently updated. Showing 50 of 206. Browse all 206 → or search them.
- Clinical Study on the Safety and the Performance of an Endometrial Ablation System in Women With Abnormal Uterine Bleeding (AUB) and Previous Cesarean Delivery.RecruitingNCT07925008Not applicable2 countries
- Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders StudyRecruitingNCT059164691 country
- Ultrasound-Guided Radiofrequency Ablation for Focal AdenomyosisNot yet recruitingNCT07906535Not applicable1 country
- A Clinical Study of the Aqua Therapeutics Thermal Therapy Vapor Ablation System in Premenopausal Women With Abnormal Uterine BleedingRecruitingNCT07877051Not applicable1 country
- HMBeacon: A Phase 2 Study to Evaluate ALN-6400 in Adult and Adolescent Female Patients With VWD and HMBRecruitingNCT07575308Phase 25 countries
- Delivering tAN to Reduce HMB: The LUNA StudyRecruitingNCT07326722Not applicable1 country
- Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical SymptomsRecruitingNCT073977154 countries
- Heavy Menstrual Bleeding and Dysmenorrhea Among Undergraduate Females in the Faculty of Medicine of Assiut UniversityNot yet recruitingNCT07852143
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)RecruitingNCT042784042 countries
- Cyclobenzaprine for Postoperative Pain in Minimally Invasive HysterectomyNot yet recruitingNCT07664956Phase 41 country
- A Registry to Gather Real World Use Data on the Cerene® Cryotherapy DeviceRecruitingNCT059226571 country
- Impact of Ehlers-Danlos Syndrome on Gynaecological HealthRecruitingNCT071512741 country
- Effect of Ginger on Heavy Menstrual Bleeding in Women With Coagulation DisordersNot yet recruitingNCT07595640Early Phase 1
- Hormonal Management of Heavy Menstrual Bleeding in AdolescentsRecruitingNCT067409291 country
- to Evaluate the Efficacy and Safety of KLH-2109 in Patients With Uterine Fibroids and MenorrhagiaRecruitingNCT07378098Phase 31 country
- Reframing Endometrial Physiology by Advanced Integrated ResearchRecruitingNCT075579921 country
- HIFU Versus Myomectomy for the Treatment of Symptomatic Uterine FibroidsRecruitingNCT06692335Not applicable1 country
- Multicenter Observational Cohort Study on the Epidemiology of Therapeutic Strategies in Patients Affected by AdenomyosisRecruitingNCT074786141 country
- Phase II Study of CMS-D002 Capsule for Uterine Fibroids With MenorrhagiaRecruitingNCT07402369Phase 21 country
- Effectiveness of an mHealth Innovation on the Impact of Menstrual Complaints in AdolescentsNot yet recruitingNCT07457957Not applicable1 country
- Clinical Spectrum and Management of Von Willebrand Disease Among Children in Assiut GovernorateNot yet recruitingNCT074101301 country
- Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine FibroidsRecruitingNCT06671548Phase 31 country
- NovaSure Study: Endometrial Ablation in Women With Heavy Menstrual BleedingRecruitingNCT05856838Not applicable1 country
- Evaluating the Reliability and Validity of the Arabic Version of the SAMANTA Questionnaire: A Step Toward Improved Diagnosis of Heavy Menstrual BleedingNot yet recruitingNCT07267611
- Prevalence and Impact on Quality of Life, Academic Performance, and Blood Indices of Heavy Menstrual Bleeding Among Female Students in Assiut University, EgyptNot yet recruitingNCT071882591 country
- Moderate Aerobic Exercise for Managing Menstrual Cycle SymptomsRecruitingNCT07084714Not applicable1 country
- Efficacy of Calcium Dobesilate Versus Tranexamic Acid for Treating Heavy Menstrual BleedingNot yet recruitingNCT06763094Not applicable
- Pattern of Menorrhagic Female Attending the Hematology Unit in Assuit University Children HospitalNot yet recruitingNCT06660459
- TRanEXamic Acid to Decrease Heavy Menstrual Bleeding in Individuals Anticoagulated for Venous Thromboembolism Pilot StudyNot yet recruitingNCT06452342Phase 4
- A Phase II/III Study of Efficacy and Safety of SHR7280 Tablets in Subjects With Menorrhagia With Uterine FibroidsRecruitingNCT05442827Phase 2/31 country
- IV Iron vs Oral Iron for Treatment of Anemia in Women With Abnormal Uterine BleedingRecruitingNCT04205266Phase 41 country
- IUB SEAD RED (Revolutionary Endometrial Ablation Device Study)RecruitingNCT05606146Not applicable1 country
- IUB SEAD RED (Revolutionary Endometrial Ablation Device StudyRecruitingNCT04959396Not applicable2 countries
- Effects of Dietary Nitrate Intake on Physical Performance of Middle-aged WomenRecruitingNCT05820321Not applicable1 country
- Heavy Menstrual Bleeding and Iron Deficiency AnemiaNot yet recruitingNCT05079815
- Juveena Hydrogel System Feasibility Study for Heavy Menstrual Bleeding (HMB)CompletedNCT06634719Not applicable1 country
- Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian SyndromeCompletedNCT07701525Phase 41 country
- GyneFix IUD Plus LNG-IUS for AdenomyosisCompletedNCT07680985Not applicable1 country
- Sleep and Health Outcomes in Women With Heavy MensesCompletedNCT05722444Not applicable1 country
- Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)WithdrawnNCT05538689Phase 41 country
- Clinical Observation of Hysteroscopy-Assisted Placement of Handmade Frameless GyneFix-LNG-IUS (Retrospective Cohort)CompletedNCT075186931 country
- Identifying the Determinants of Bleeding and Hypermobility in Patients With Heavy Menstrual BleedingTerminatedNCT056851991 country
- Efficiency of Lina LibrataTM SystemCompletedNCT03670680Not applicable1 country
- Post Market TRUST - U.S.A. StudyCompletedNCT02163525Not applicable1 country
- Transcutaneous Auricular Neurostimulation as a Treatment for Women With Heavy Menstrual Bleeding: A Dose-finding TrialCompletedNCT06814028Not applicable1 country
- A Study to Evaluate Changes in Hair in Adult Participants Taking Oral Oriahnn Capsules With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF)WithdrawnNCT060587281 country
- Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal WomenCompletedNCT03271489Phase 32 countries
- Impact of Incomplete Endometrial AblationActive, not recruitingNCT061223631 country
- Delivering Transcutaneous Auricular Neurostimulation to Reduce Heavy Menstrual Bleeding in Patients With and Without Von Willebrand DiseaseCompletedNCT06064851Not applicable1 country
- Menstrual Complaints in Adolescents and AdultsActive, not recruitingNCT069216291 country