Drug
Ranibizumab clinical trials
Also written RFB002.
Keep track of what changes. Save the Ranibizumab studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
349 studies that test it; most in 2007 (38)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2002 | 1 |
| 2003 | 3 |
| 2004 | 5 |
| 2005 | 8 |
| 2006 | 18 |
| 2007 | 38 |
| 2008 | 35 |
| 2009 | 24 |
| 2010 | 32 |
| 2011 | 28 |
| 2012 | 19 |
| 2013 | 27 |
| 2014 | 23 |
| 2015 | 24 |
| 2016 | 14 |
| 2017 | 11 |
| 2018 | 4 |
| 2019 | 5 |
| 2020 | 6 |
| 2021 | 10 |
| 2022 | 3 |
| 2023 | 3 |
| 2024 | 3 |
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 108 · Other 242
Novartis Pharmaceuticals (40) · Genentech, Inc. (17) · Novartis (11) · Hoffmann-La Roche (8) · National Eye Institute (NEI) (7) · California Retina Consultants (6) · Vitreous -Retina- Macula Consultants of New York (6) · University of Miami (5)
Often tested with
Tested in the same studies.
Bevacizumab (16) · Aflibercept (14) · Dexamethasone (9) · Verteporfin (7) · Dexamethasone Intravitreal Implant (4) · Photodynamic Therapy (4) · DRUG 601 (2) · LKA651 (2)
Related medicines
As reviewed, each with the page that says it.
- One of Angiogenesis Inhibitors source
Studies
Open first, then newest update. How each study uses Ranibizumab is read from its arms, and is right about nine times in ten.
Testing it · 350
- A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMDRecruitingPhase 3Hoffmann-La RocheNCT06847542Written as Ranibizumab
- Continuous Delivery of Ranibizumab Via the Port Delivery System for Proliferative Diabetic Retinopathy-related Vitreous Hemorrhage With Pars Plana Vitrectomy and Limited PRP.Not yet recruitingPhase 4Southeast Retina Center, GeorgiaNCT07864480Written as Ranibizumab
- A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)RecruitingPhase 4Genentech, Inc.NCT04853251Written as LUCENTIS (Ranibizumab Injection)
- Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMDEnrolling by invitationPhase 2AbbVieNCT05210803Written as Ranibizumab
- Efficacy, Safety, pharmacokinetiсs, Immunogenicity of GNR-067 and Lucentis®RecruitingPhase 3AO GENERIUMNCT04667039Written as GNR-067
- Study on Precision Treatment of Diabetic Retinopathy Macular Edema Guided by Real-time OCT During OperationRecruitingPhase 3Affiliated Hospital of Nantong UniversityNCT05138029Written as Ranibizumab Injection [Lucentis]
- A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular EdemaCompletedPhase 3Incepta Pharmaceuticals LtdNCT06305416Written as Ranibizumab 10mg/ml Injection
- Laser Photocoagulation and Ranibizumab Treatment in Proliferative Diabetic RetinopathyCompletedNot applicableAswan UniversityNCT07819253Written as Ranibizumab 0.5 mg
- Study of Zifibancimig in Participants With Neovascular Age-related Macular DegenerationCompletedPhase 1/2Hoffmann-La RocheNCT04567303Written as Ranibizumab
- A Study of the Efficacy, Safety, and Pharmacokinetics (PK) of the Port Delivery System With Ranibizumab (PDS) in Chinese Participants With Neovascular Age-related Macular Degeneration (nAMD)Active, not recruitingPhase 3Hoffmann-La RocheNCT05562947Written as Ranibizumab (10 mg/mL)
- A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)Active, not recruitingPhase 3Hoffmann-La RocheNCT04657289Written as Ranibizumab
- Intravitreal Ranibizumab for Aggressive Posterior Retinopathy of Prematurity: A Prospective Interventional Case SeriesCompletedNot applicableAin Shams UniversityNCT07721298Written as Intravitreal Ranibizumab injection
- Outcomes of Intravitreal Ranibizumab Injection for Diabetic Vitreous HemorrhageCompletedPhase 4Benha UniversityNCT07690800Written as Ranibizumab
- A Study to Evaluate the Usability of the SB11 PFS in Trial Participants With Wet AMD, Macular Oedema Secondary to RVO, or mCNVCompletedPhase 2Samsung Bioepis Co., Ltd.NCT07550504Written as SB11 PFS
- A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator ArmCompletedPhase 3Hoffmann-La RocheNCT04503551Written as Intravitreal Ranibizumab 0.5 mg Injection
- A Study to Compare JL14002 to Lucentis® in Subjects With Wet Age-related Macular Degeneration (wAMD)CompletedPhase 3Jecho Biopharmaceuticals Co., Ltd.NCT07389577Written as Ranibizumab(Fixed dosing regimen)
- Stereotactic Radiotherapy for Wet AMD (STAR)CompletedPhase 3King's College Hospital NHS TrustNCT02243878Written as 0.5 mg ranibizumab
- 601 Versus Ranibizumab in Patients With Central Retinal Vein Occlusion (CRVO)CompletedPhase 2Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.NCT04667910Written as Ranibizuman 0.5 mg
- 601 Versus Ranibizumab in Patients With Branch Retinal Vein Occlusion (BRVO)CompletedPhase 2Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.NCT04667897Written as Ranibizuman 0.5 mg
- ZIMURA in Combination With LUCENTIS in Patients With Neovascular Age Related Macular Degeneration (NVAMD)CompletedPhase 2Ophthotech CorporationNCT03362190Written as Lucentis
See all 350 studies that test Ranibizumab →
Given in every arm · 58 — Ranibizumab is usual care beside what is tested
- Identification of Molecular Signals in Vitreous Humor Associated With Suboptimal Response to Vascular Endothelial Growth Factor (VEGF) Inhibition in Neovascular Age-related Macular Degeneration (nAMD) Within a Clinical Trial SettingRecruitingNot applicableSingapore National Eye CentreNCT07249216Written as Ranibizumab
- Combination of Ranibizumab and Targeted Laser PhotocoagulationActive, not recruitingPhase 3University of GiessenNCT04444492Written as Ranibizumab Injection
- Ranibizumab and Reduced Fluence PDT for AMDCompletedPhase 2Texas Retina AssociatesNCT00527475Written as ranibizumab
- A Study to Investigate Vamikibart (RO7200220) in Combination With Ranibizumab in Diabetic Macular EdemaCompletedPhase 2Hoffmann-La RocheNCT05151744Written as Ranibizumab
- Manage Macular Cystoid Edema With Retinal Vein Obstruction Using Traditional Chinese Medicine and RanibizumabCompletedPhase 4Dongyang People's HospitalNCT06234514Written as intravitreal injections of 0.5mg ranibizumab
- OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD)TerminatedPhase 3Opthea LimitedNCT04757610Written as 0.5 mg ranibizumab
- Safety Study of Zimura in Combination With Anti-VEGF Therapy in Patients With Neovascular AMDTerminatedPhase 2IVERIC bio, Inc.NCT05571267Written as Lucentis
- A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® MonotherapyTerminatedPhase 3Ophthotech CorporationNCT01940900Written as ranibizumab
- A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® MonotherapyTerminatedPhase 3Ophthotech CorporationNCT01944839Written as ranibizumab
- Optical Coherence Tomography Angiography (OCTA) - Directed PDT Triple TherapyWithdrawnPhase 4Wake Forest University Health SciencesNCT04075136Written as Ranibizumab
- Combined Ranibizumab and Iluvien for Diabetic Macular OedemaWithdrawnPhase 2/3Imperial College LondonNCT03784443Written as Ranibizumab Injection [Lucentis]
- Noctura400 Treatment for Diabetic Retinopathy (CANDLE)TerminatedNot applicablePolyPhotonix MedicalNCT02207712Written as Ranibizumab
- Combination of Intravitreal Ranibizumab With or Without Macular Laser Photocoagulation for ME Secondary to BRVOCompletedNot applicableBeijing HospitalNCT03054766Written as Ranibizumab
- Combination of Intravitreal Ranibizumab With or Without Micropulse Laser for the Treatment of DMECompletedPhase 4Beijing HospitalNCT03690947Written as Intravitreal Ranibizumab
- Evaluation of the Safety and Efficacy of ALS-L1023 Administered in Combination With Ranibizumab in Patients With Wet-AMDCompletedPhase 2AngioLab, Inc.NCT03725501Written as Ranibizumab
- Brolucizumab vs. Aflibercept for Retinal Angiomatous ProliferationWithdrawnPhase 4Faculty Hospital Kralovske VinohradyNCT04698850Written as Ranibizumab 6 MG/ML [Lucentis]
- Phacoemulsification Combined With Intravitreal Injection of Ranibizumab Prevent Postoperative Capillary Non-perfusion Zone Progress in Non-proliferative Diabetic RetinopathyStatus unknownPhase 4Ruijin HospitalNCT05386160Written as Ranibizumab Injection [Lucentis]
- Study of the Efficacy and Tolerability of Intravitreal Injections of Ranibizumab Compared to Intravitreal Injections of Ranibizumab Combined With Targeted Retinal Photocoagulation to Treat Radiation Retinopathy.CompletedPhase 2Greater Houston Retina ResearchNCT02222610Written as 0.5 mg ranibizumab
- A Dose Ranging Study of OPT-302 With Ranibizumab in Neovascular (Wet) AMDCompletedPhase 2Opthea LimitedNCT03345082Written as ranibizumab
- Macular EpiRetinal Brachytherapy Versus Lucentis® Only Treatment (MERLOT)CompletedPhase 4King's College Hospital NHS TrustNCT01006538Written as Ranibizumab
Showing 20 of 58.
As the comparator · 59 — what is tested is compared with Ranibizumab
- Phase 3 Study of Intravitreal OLN324 in Adults With Neovascular (Wet) Age-related Macular Degeneration (nAMD) (OLN324-CP-05)Not yet recruitingPhase 3Ollin Biosciences, Inc.NCT07816289Written as Ranibizumab
- Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Diabetic Macular EdemaRecruitingPhase 3Bio-Thera SolutionsNCT07515079Written as Lucentis
- Pharmacogenomics of antiVEGF in Patients With Age-Associated Macular Degeneration (AMD)RecruitingPhase 3Parc de Salut MarNCT06952452Written as Ranibizumab Ophthalmic
- This Study Will Compare the Efficacy and Safety of SCT510A Administered by Intravitreal Injection (IVT) With Ranibizumab in Patients With wAMDRecruitingPhase 3Sinocelltech Ltd.NCT05480293Written as Ranibizumab
- A Study of 2 Doses of Remigromig (EYE103) Compared With Ranibizumab (0.5 mg) in Participants With DMEActive, not recruitingPhase 2/3EyeBiotech Ltd.NCT06957080Written as Ranibizumab
- A Study to Evaluate the Efficacy and Safety of 2 Doses of Remigromig (EYE103) Compared With Ranibizumab (0.5 mg) in Participants With DMEActive, not recruitingPhase 2/3EyeBiotech Ltd.NCT06571045Written as Ranibizumab
- Clinical Study to Evaluate PRO-169 for Diabetic Macular EdemaCompletedPhase 3Laboratorios Sophia S.A de C.V.NCT05217680Written as Lucentis®
- A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DMEActive, not recruitingPhase 3Hoffmann-La RocheNCT04108156Written as Intravitreal Ranibizumab 0.5 mg Injection
- A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)CompletedPhase 3Outlook Therapeutics, Inc.NCT03834753Written as ranibizumab
- A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic MyopiaCompletedPhase 3Hoffmann-La RocheNCT06176352Written as Ranibizumab
- A 3-month Study to Assess the Safety and Effectiveness of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)CompletedPhase 3Outlook Therapeutics, Inc.NCT06190093Written as ranibizumab
- A Study to Investigate Vamikibart (RO7200220) in Diabetic Macular EdemaCompletedPhase 2Hoffmann-La RocheNCT05151731Written as Ranibizumab
- Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMDActive, not recruitingPhase 2/3AbbVieNCT04704921Written as Ranibizumab (LUCENTIS®)
- RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD)Active, not recruitingPhase 2AbbVieNCT04514653Written as Ranibizumab
- Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMDCompletedPhase 3Lupin Ltd.NCT04690556Written as Lucentis (ranibizumab)
- A Phase III Study for 601 Versus Ranibizumab in Patients With Vision LossCompletedPhase 3Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.NCT05520177Written as ranibizumab 0.5mg
- Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Macular DegenerationCompletedPhase 3Bio-Thera SolutionsNCT05439629Written as Lucentis
- Steroid vs. Anti-vascular Endothelial Growth Factor for Diabetic Macular Edema Prior to PhacoemulsificationCompletedPhase 4Bay Area Retina AssociatesNCT03832179Written as Ranibizumab
- Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMDCompletedPhase 3Shanghai Henlius BiotechNCT05003245Written as Lucentis
- A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)CompletedPhase 3Outlook Therapeutics, Inc.NCT03844074Written as ranibizumab
Showing 20 of 59.
Codes
What other systems call Ranibizumab · ClinicalTrials.gg INT006612
- MeSH (NLM) D000069579RanibizumabConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) ZL1R02VT79RANIBIZUMABConfirmed FDA, NLM, Wikidata
- RxNorm 595060Confirmed FDA, Wikidata
- Wikidata Q414270ranibizumabConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C67562RanibizumabOne source FDA
- DrugBank DB01270One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069579 | Ranibizumab | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | ZL1R02VT79 | RANIBIZUMAB | Confirmed FDA, NLM, Wikidata |
| RxNorm | 595060 | — | Confirmed FDA, Wikidata |
| Wikidata | Q414270 | ranibizumab | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C67562 | Ranibizumab | One source FDA |
| DrugBank | DB01270 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.