Duodenal Ulcer clinical trials
The registry lists 79 studies for Duodenal Ulcer across more than 10 countries. 5 are recruiting or about to start. 33 of them are mainly about Duodenal Ulcer (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
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Who runs them
Takeda (18) · AstraZeneca (15) · Eisai Co., Ltd. (3) · Livzon Pharmaceutical Group Inc. (3) · Hamamatsu University (3) · Boryung Pharmaceutical Co., Ltd (3) · The Catholic University of Korea (2) · Valenta Pharm JSC (2)
What is being tested here
Drugs under test in Duodenal Ulcer studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Aspirin | 1 | 1 | 2 |
| Fexuprazan | 1 | 1 | 1 |
| Vonoprazan | 0 | 8 | 8 |
| Lansoprazole | 0 | 5 | 6 |
| Esomeprazole | 0 | 4 | 5 |
| Rabeprazole | 0 | 3 | 4 |
| Amoxicillin | 0 | 2 | 4 |
| D961H | 0 | 2 | 3 |
| Ilaprazole | 0 | 2 | 3 |
| Clarithromycin | 0 | 2 | 3 |
Drug classes tested here Proton pump inhibitors (PPIs) 20
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Jan 2027Comparison of Open vs Laparoscopic Repair of Perforated Duodenal Ulcer · Allied Hospital Faisalabad
- Feb 2027Efficacy and Safety of Esomeprazole 40 mg IV in Post-Surgical Patients Admitted to the ICU · Asian Institute of Gastroenterology, India
Who these studies take
Of the 3 Duodenal Ulcer studies recruiting now, 1 (33%) set no upper age limit and 2 (67%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 3 (100%) | 3 (100%) |
| 30 | 3 (100%) | 3 (100%) |
| 40 | 3 (100%) | 3 (100%) |
| 50 | 2 (67%) | 2 (67%) |
| 65 | 2 (67%) | 2 (67%) |
| 75 | 2 (67%) | 2 (67%) |
| 85 | 1 (33%) | 1 (33%) |
Across all 79 studies, recruiting or not: 32% stop at 75 or younger and 22% at 65; 28% take children; 0% are for women only and 3% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 79. Browse all 79 → or search them.
- Comparison of Open vs Laparoscopic Repair of Perforated Duodenal UlcerNot yet recruitingNCT07893951Not applicable1 country
- Efficacy and Safety of Esomeprazole 40 mg IV in Post-Surgical Patients Admitted to the ICURecruitingNCT073990541 country
- Phase 3 to Evaluate the Efficacy and Safety of DWP14012 in Patients With Gastric UlcerNot yet recruitingNCT07730138Phase 32 countries
- Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic DiseaseRecruitingNCT06541691Not applicable1 country
- Comparative Pharmacodynamics and Pharmacodynamics Equivalence of Antareit 800 mg/10 ml Oral Suspension and Riopan 800 mg Chewable Tablets in Healthy VolunteersRecruitingNCT06098742Not applicable1 country
- To Develop Methods for the Rehabilitation of Chronic Gastroduodenal Pathology in Children.Active, not recruitingNCT04702542Not applicable1 country
- Stress Ulcer Prophylaxis in the Intensive Care UnitCompletedNCT02467621Phase 46 countries
- Pharmacist-Driven Stress Ulcer Prophylaxis Minimization in the Intensive Care UnitCompletedNCT062251671 country
- A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal UlcerCompletedNCT03553563Phase 31 country
- Optimizing Stress Ulcer Prophylaxis Practices and Reducing Associated Costs in Intensive Care Units: a Nonrandomized Controlled StudyCompletedNCT06586333Not applicable1 country
- Comparative Pharmacodynamics and Pharmacodynamics Equivalence of Antareit 800 mg Chewable Tablets and Riopan 800 mg Chewable Tablets in Healthy VolunteersCompletedNCT06552624Not applicable1 country
- A Study to Evaluate the Drug-drug Interaction and Safety Between "BR6001-1" and "BR6001-2"CompletedNCT06165237Phase 11 country
- Systems Biology of Gastrointestinal and Related DiseasesTerminatedNCT055794441 country
- A Study to Evaluate the Pharmacokinetics and Safety Between Single Administration of "BR6002" and Coadministration of "BR6002A" and "BR6002B" Under Fasting Conditions in Healthy Adult VolunteersCompletedNCT05959486Phase 11 country
- A Study to Evaluate the Pharmacokinetics and Safety Between Single Administration of "BR6002" and Coadministration of "BR6002A" and "BR6002B" Under Fed Conditions in Healthy Adult VolunteersCompletedNCT05959499Phase 11 country
- Special Drug Use Surveillance of Vonoprazan for "Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Non-steroidal Anti-inflammatory Drugs: Long-term Use"CompletedNCT032141981 country
- Efficacy and Safety of LXI-15028 Comparing With Lansoprazole in the Treatment of Duodenal UlcerCompletedNCT05010954Phase 31 country
- A Study of Pariet to Prevent Gastric and Duodenal Ulcer Associated With Low-aspirin in Korean Participants With a History of Gastric and Duodenal UlcerCompletedNCT052082681 country
- Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart DiseaseCompletedNCT03667703Phase 41 country
- The Efficacy and Safety of Ilaprazole/Doxycycline-based Bismuth-containing Quadruple Therapy on Hp Infected Duodenal UlcersCompletedNCT03342456Phase 41 country
- Scoring System in Predicting Perforated Duodenal Ulcer Morbidity and Mortality in BpkihsCompletedNCT049941841 country
- Helicobacter Pylori Eradication With a New Sequential TreatmentCompletedNCT00132171Phase 31 country
- A Phase 2 Randomised Controlled Trial to Evaluate Efficacy and Safety of Anaprazole in Patients With Duodenal Ulcers.CompletedNCT04503629Phase 21 country
- Early Oral Feeding vs Traditional Post-operative Care In Emergency Abdominal SurgeriesCompletedNCT04431037Not applicable1 country
- Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Duodenal Ulcer Participants With or Without Helicobacter Pylori InfectionCompletedNCT03050359Phase 34 countries
- Special Drug Use Surveillance of Vonoprazan for "Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Low-dose Aspirin: Long-term Use"CompletedNCT032140941 country
- A Phase 3 Randomised Controlled Trial to Evaluate Efficacy and Safety of Anaprazole in Patients With Duodenal Ulcers.Status unknownNCT04215653Phase 3
- Drug Use Surveillance of Vonoprazan for "Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis"CompletedNCT032149521 country
- Nexium Capsules Non-steroidal Anti-inflammatory Drug (NSAID) Specific Clinical Experience InvestigationCompletedNCT015626001 country
- Nexium Capsules LDA Specific Clinical Experience InvestigationCompletedNCT017291821 country
- Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"CompletedNCT032197231 country
- A Study on the Gastrointestinal Disease and Helicobacter Pylori Controlled Long Non-coding RNAStatus unknownNCT030571711 country
- Rabeprazole Specific Clinical Experience Investigation for the Long-term Combination Therapy With Low-dose AspirinCompletedNCT024231871 country
- Effect of Second-look Endoscopy on Peptic Ulcer Rebleeding in Patients With Early Resumption of Antiplatelet AgentsTerminatedNCT02840929Not applicable2 countries
- China Survey of Stress Ulcer Bleeding in Critically Ill Neurosurgical PatientsCompletedNCT023169901 country
- A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related DiseasesCompletedNCT02153398Phase 31 country
- Long-term Use of Takepron Capsules on the Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Low-dose AspirinCompletedNCT02099682
- Long-term Use of Takepron on the Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Non-steroidal Anti-inflammatory DrugsCompletedNCT02099708
- Ilaprazole for the Treatment of Duodenal Ulcer in Chinese PatientsCompletedNCT02847455Phase 2/3
- Lansoprazole Intravenous 30 mg Specified Drug-use Survey [Hemostatic Effect/Rebleeding Rate]CompletedNCT02151786
- Long-term Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)CompletedNCT01398410Phase 2/31 country
- MK0782 + Low-Dose Aspirin 7-Day Erosion Endoscopy Study (0782-001)CompletedNCT00543868Phase 2
- Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)CompletedNCT01397448Phase 2/31 country
- Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose AspirinCompletedNCT01456247Phase 31 country
- Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Non-steroidal Anti-inflammatory Drug (NSAID)CompletedNCT01456260Phase 31 country
- Nexium Capsules Clinical Experience InvestigationCompletedNCT014344851 country
- Nexium Capsules Helicobacter Pylori Specific Clinical Experience InvestigationCompletedNCT014355251 country
- Efficacy and Safety of L-Pantoprazole Sodium Injection to Treat Upper Gastrointestinal Ulcer BleedingStatus unknownNCT02108756Not applicable1 country
- Concomitant Therapy of H. PyloriStatus unknownNCT01922765Phase 41 country
- A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Low-Dose Aspirin TherapyCompletedNCT01568398Phase 31 country