Rhinitis, Allergic, Seasonal clinical trials
The registry lists 404 studies for Rhinitis, Allergic, Seasonal across more than 10 countries. 24 are recruiting or about to start. 349 of them are mainly about Rhinitis, Allergic, Seasonal (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.
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Status
Who runs them
Organon and Co (37) · GlaxoSmithKline (31) · AstraZeneca (14) · Meda Pharmaceuticals (10) · UCB Pharma (9) · Fraunhofer-Institute of Toxicology and Experimental Medicine (9) · Stallergenes Greer (7) · University of Chicago (7)
What is being tested here
Drugs under test in Rhinitis, Allergic, Seasonal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Stapokibart | 3 | 1 | 3 |
| Telikibart | 2 | 2 | 2 |
| TQH2722 | 1 | 0 | 2 |
| AK139 | 1 | 0 | 1 |
| Fluticasone | 0 | 14 | 28 |
| Mometasone Furoate | 0 | 10 | 18 |
| Azelastine | 0 | 9 | 16 |
| Montelukast | 0 | 11 | 14 |
| Fluticasone furoate | 0 | 8 | 14 |
| Ciclesonide | 0 | 11 | 11 |
Drug classes tested here Antihistamines 70 · Corticosteroids 68
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10, phase 3 first
- Dec 2026A Clinical Study Evaluating the Efficacy and Safety of SHR-1819 Injection in Patients With Seasonal Allergic Rhinitis · Phase 3 · Guangdong Hengrui Pharmaceutical Co., Ltd
- Dec 2026Study on the Treatment of Adolescent Patients With Seasonal Allergic Rhinitis · Phase 3 · Chengdu Kangnuoxing Biopharma,Inc.
- May 2027A Study of GR1802 Injection in Patients With Seasonal Allergic Rhinitis. · Phase 3 · Genrix (Shanghai) Biopharmaceutical Co., Ltd.
- Oct 2027Rupatifen Fumarate Capsules in Patients With Seasonal Allergic Rhinitis · Phase 3 · Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd.
- Nov 2026Clinical Study on TQH2722 Injection Combined With Background Therapy for Seasonal Allergic Rhinitis · Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.
- Dec 2026Tezepelumab in Allergic Rhinitis and Asthma Study (TEZARS) · Dr. Anne Ellis
- Dec 2026The Role of the Nasal Allergen Provocation Test in Starting and Monitoring Allergen Immunotherapy · Universitaire Ziekenhuizen KU Leuven
- Mar 2027Safety, Tolerability And Pharmacodynamics of DM-101PX in Birch Pollen Allergy · Desentum Oy
- May 2027Identification of B Regulatory Cells by Flow Cytometry · Hull University Teaching Hospitals NHS Trust
- Jul 2027Evaluation of the Efficacy, Safety, and Tolerability of PL-14 Allergy Blocker Compared to Saline Spray in Patients With Seasonal Allergic Rhinitis · Polyrizon Ltd.
Who these studies take
Of the 17 Rhinitis, Allergic, Seasonal studies recruiting now, 2 (12%) set no upper age limit and 15 (88%) stop at 75 or younger. 1 (6%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 17 (100%) | 17 (100%) |
| 30 | 16 (94%) | 16 (94%) |
| 40 | 16 (94%) | 16 (94%) |
| 50 | 16 (94%) | 16 (94%) |
| 65 | 14 (82%) | 14 (82%) |
| 75 | 7 (41%) | 7 (41%) |
| 85 | 2 (12%) | 2 (12%) |
Across all 404 studies, recruiting or not: 67% stop at 75 or younger and 60% at 65; 37% take children; <1% are for women only and 2% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Rhinitis, Allergic, Seasonal studies take
Of 37 phase 3 interventional studies under Rhinitis, Allergic, Seasonal, half reached primary completion within 4 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 5 mo4–9 · 16 studies | — | — |
| Phase 2 | 5 mo3–23 · 24 studies | — | — |
| Phase 3 | 4 mo2–14 · 37 studies | 4 mo1–14 · 31 studies | — |
| Interventional, no phase | 7 mo2–22 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 404. Browse all 404 → or search them.
- Safety, Tolerability And Pharmacodynamics of DM-101PX in Birch Pollen AllergyRecruitingNCT07898800Phase 11 country
- Identification of Allergen-reactive Antibodies in the Blood of Pollen Allergic PatientsEnrolling by invitationNCT037273991 country
- Investigating Nasal and Ocular Immune Response to Conjunctival Allergen ExposureRecruitingNCT078016251 country
- Evaluation of the Efficacy, Safety, and Tolerability of PL-14 Allergy Blocker Compared to Saline Spray in Patients With Seasonal Allergic RhinitisRecruitingNCT07588672Not applicable1 country
- Phase 1, First in Human (FIH), Open-Label, Single-Arm, Ascending Dose Study to Assess the Safety, Tolerability and Preliminary Immunogenicity of ITI-9001 in Japanese Patients With Japanese Red Cedar (JRC) PollinosisRecruitingNCT07726147Phase 11 country
- Identification of B Regulatory Cells by Flow CytometryRecruitingNCT068765061 country
- Rupatifen Fumarate Capsules in Patients With Seasonal Allergic RhinitisRecruitingNCT07711262Phase 31 country
- Study on the Treatment of Adolescent Patients With Seasonal Allergic RhinitisRecruitingNCT07678931Phase 31 country
- Study of Stapokibart Injection in Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)Not yet recruitingNCT07617324Phase 21 country
- Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA StudyRecruitingNCT07055542Not applicable1 country
- The Role of the Nasal Allergen Provocation Test in Starting and Monitoring Allergen ImmunotherapyRecruitingNCT045447741 country
- Clinical Study on TQH2722 Injection Combined With Background Therapy for Seasonal Allergic RhinitisRecruitingNCT07398859Phase 21 country
- A Study to Evaluate the Efficacy and Safety of AK139 in Participants With Seasonal Allergic RhinitisNot yet recruitingNCT07436234Phase 21 country
- A Study to Determine the Optimal Dose and Frequency of ALDP001 Nasal Spray in Adults With Seasonal Allergic Rhinitis Under Allergen ExposureRecruitingNCT07219849Phase 21 country
- A Study of GR1802 Injection in Patients With Seasonal Allergic Rhinitis.Not yet recruitingNCT07199257Phase 31 country
- Study of CM310 in Patients With Uncontrolled Seasonal Allergic RhinitisRecruitingNCT06300203Phase 21 country
- A Study of IL4Rα Monoclonal Antibody in Patients With Seasonal Allergic RhinitisRecruitingNCT07154342Phase 31 country
- A Phase III Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic RhinitisNot yet recruitingNCT07146126Phase 31 country
- Acupuncture at the Sphenopalatine Ganglion in the Treatment of Moderate-to-severe Seasonal Allergic RhinitisRecruitingNCT04815668Not applicable1 country
- Quercus Ilex and Quercus Robur Allergen Extracts StandardisationRecruitingNCT05532566Not applicable1 country
- Phase II/III Seamless Clinical Study of MG-K10 Humanized Monoclonal Antibody Injection in Treatment of Seasonal Allergic RhinitisRecruitingNCT06846385Phase 2/31 country
- Impacts of Nitrogen Deposition in the Natural Environment on Pollen Allergy in BelgiumRecruitingNCT06714149Not applicable1 country
- Study of CM310 in Subjects With Seasonal Allergic RhinitisNot yet recruitingNCT06171074Phase 21 country
- Allergy Diagnostic Test Based on Microchip TechnologyNot yet recruitingNCT06167564Not applicable1 country
- A Clinical Study Evaluating the Efficacy and Safety of SHR-1819 Injection in Patients With Seasonal Allergic RhinitisActive, not recruitingNCT07688772Phase 31 country
- A Multicenter, Randomized, Double-blind, Three-arm, Parallel Clinical Endpoint Bioequivalence Study of Monometasone Furoate Nasal Spray in Patients With Seasonal Allergic RhinitisCompletedNCT06200766Phase 31 country
- Allergen Challenge Trial of IRL201104 in Seasonal Allergic RhinitisCompletedNCT05098522Phase 21 country
- A Clinical Trial for Evaluation of Efficacy, Safety and Immunogenicity of GNR-127 (Recombinant ABP Antigen Protein Which Carries a Birch Pollen Allergen [BET V 1] and an Apple Allergen [MAL D 1]) in Patients With Birch Pollen Allergic Rhinitis.CompletedNCT07155499Phase 1/21 country
- A Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic RhinitisCompletedNCT06837233Phase 21 country
- Study of DM-101PX in Adults With Birch Pollen AllergyCompletedNCT07254871Phase 21 country
- A Clinical Study on the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of SHR-1819 Injection in Patients With Seasonal Allergic RhinitisCompletedNCT07091357Phase 21 country
- Threshold Concentrations for Ragweed and Birch Pollen in Seasonal Allergic RhinitisCompletedNCT05346718Not applicable1 country
- An Exploratory Study of PQ Grass 27600 SUCompletedNCT04687059Phase 2/32 countries
- Grass Pollen Immunotherapy Plus Dupilumab for Tolerance InductionCompletedNCT04502966Phase 21 country
- Special Drug Use Observational Study of Xolair in Patients With Severe to Most Severe Seasonal Allergic Rhinitis Aged ≥ 12 Years and < 18 Years Whose Symptoms Were Inadequately Controlled Despite to Conventional TherapiesCompletedNCT04648930
- Clinical Trial of TQC2938 Injection in Patients With Seasonal Allergic RhinitisCompletedNCT07052097Phase 21 country
- Tyrosine Allergoid Paediatric and Adult StudyActive, not recruitingNCT051860251 country
- Tezepelumab in Allergic Rhinitis and Asthma Study (TEZARS)Active, not recruitingNCT06189742Phase 21 country
- Study of Efficacy and Safety of Omalizumab in Severe Japanese Cedar Pollinosis Adult and Adolescent PatientsCompletedNCT03369704Phase 31 country
- Efficacy and Safety of LP-003 Injection in Patients With Moderate to Severe Seasonal Allergic RhinitisActive, not recruitingNCT07291284Phase 31 country
- Efficacy and Safety of LP-003 in Moderate-to-severe Seasonal Allergic Rhinitis AdultCompletedNCT06046391Phase 21 country
- A Clinical Pharmacology Study of MT-2990 in Seasonal Allergic Rhinitis PatientsCompletedNCT03570957Phase 11 country
- Safety and Efficacy of STALORAL® Birch 300 IR in a Paediatric Population With Birch Pollen-induced ARC w/o AsthmaCompletedNCT05668390Phase 312 countries
- Phleum Pratense and Dactylis Glomerata Allergen Extracts StandardizationCompletedNCT06957496Not applicable1 country
- Nasal Allergen Challenge Test as a Method to Detect Clinical Reactivity Against Birch PollenCompletedNCT06085963Not applicable1 country
- A Placebo-controlled Study of 2-day Pre-treatment With Fexofenadine in Seasonal Allergic RhinitisCompletedNCT05692154Phase 31 country
- Clinical Trial of TQH2722 Injection in Patients With Seasonal Allergic RhinitisCompletedNCT06760182Phase 21 country
- A Motivation-enhancing App to Retain Patients With Hay Fever in a Trial After TreatmentCompletedNCT05560698Not applicable1 country
- Phase II Study of JT002 in the Treatment of Seasonal Allergic Rhinitis in AdultsCompletedNCT06861101Phase 21 country
- Immunological Analysis of Lymph Node Tissue After Intralymphatic Immunotherapy: A Prospective Case Control StudyCompletedNCT05960266Early Phase 11 country