Nasal Polyps clinical trials
The registry lists 236 studies for Nasal Polyps across more than 10 countries. 68 are recruiting or about to start. 189 of them are mainly about Nasal Polyps (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Status
Who runs them
Sanofi (13) · GlaxoSmithKline (9) · Beijing Tongren Hospital (8) · AstraZeneca (8) · Assiut University (5) · Brigham and Women's Hospital (5) · Keymed Biosciences Co.Ltd (4) · Optinose US Inc. (4)
What is being tested here
Drugs under test in Nasal Polyps studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dupilumab | 3 | 2 | 9 |
| Felcorekibart | 2 | 2 | 2 |
| Omalizumab | 1 | 3 | 8 |
| Budesonide | 1 | 2 | 6 |
| Mepolizumab | 1 | 2 | 5 |
| Depemokimab | 1 | 2 | 3 |
| Stapokibart | 1 | 0 | 2 |
| Triamcinolone | 1 | 1 | 2 |
| Thymoquinone | 1 | 0 | 1 |
| Triamcinolone Acetonide | 1 | 1 | 1 |
Drug classes tested here Corticosteroids 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps · Phase 3 · Sanofi
- Mar 2027Clinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal Polyps · Phase 3 · Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.
- May 2027A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) · Phase 3 · Eli Lilly and Company
- Nov 2026Comparison of Intraoperative Outcomes of Microdebrider-Assisted Versus Conventional Functional Endoscopic Sinus Surgery in Patients With Sinonasal Polyposis · Lahore General Hospital
- Dec 2026Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis With Nasal Polyps · Harran University
- Dec 2026Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training · The Cleveland Clinic
- Dec 2026Mepolizumab and in Office-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). · Instituto de Investigación Marqués de Valdecilla
- Jan 2027Mepolizumab and In-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). A Three Arm Study. · Instituto de Investigación Marqués de Valdecilla
- Feb 2027A Study to Evaluate the Efficacy and Safety of LP-003 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) · Longbio Pharma
- Mar 2027Evaluation of the Safety and Performance of a Bioresorbable Nasal Dressing Containing Mometasone Furoate (MF) · Polyganics BV
Who these studies take
Of the 40 Nasal Polyps studies recruiting now, 22 (55%) set no upper age limit and 12 (30%) stop at 75 or younger. 2 (5%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (18%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 38 (95%) | 38 (95%) |
| 30 | 39 (98%) | 39 (98%) |
| 40 | 39 (98%) | 39 (98%) |
| 50 | 39 (98%) | 39 (98%) |
| 65 | 38 (95%) | 38 (95%) |
| 75 | 32 (80%) | 32 (80%) |
| 85 | 25 (63%) | 25 (63%) |
Across all 236 studies, recruiting or not: 39% stop at 75 or younger and 12% at 65; 7% take children; 0% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Nasal Polyps studies take
Of 34 phase 3 interventional studies under Nasal Polyps, half reached primary completion within 22 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 23 mo18–32 · 24 studies | — | — |
| Phase 3 | 22 mo19–27 · 34 studies | 22 mo15–26 · 30 studies | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting1
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 236. Browse all 236 → or search them.
- Biologics in Chronic Rhinosinusitis With Nasal PolyposisRecruitingNCT06824649Phase 41 country
- Tezepelumab CRSwNP Real World Study (CREW Study)Not yet recruitingNCT077901981 country
- A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)RecruitingNCT07782970Phase 33 countries
- A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)RecruitingNCT06338995Phase 320 countries
- Paclitaxel-Coated Balloon Treatment of Chronic RhinosinusitisRecruitingNCT07290140Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of MG-K10 in Adults With Chronic Rhinosinusitis With Nasal PolypsNot yet recruitingNCT07903194Phase 3
- Prospective, Non-interventional Single-arm Study With Tezepelumab to Investigate the Change in Clinical and Patient-reported Outcomes in Patients With CRSwNP in Real-world (PETRICHOR)RecruitingNCT076331581 country
- FESS With or Without Intranasal Desmopressin in Chronic Rhinosinusitis With Nasal PolypsNot yet recruitingNCT07855315Not applicable
- Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis With Nasal PolypsRecruitingNCT078604111 country
- A Study to Investigate NPS and Symptoms in Chinese Adult Participants With CRSwNP Initiating Treatment With TezepelumabRecruitingNCT07520162Phase 31 country
- A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)RecruitingNCT07782957Phase 32 countries
- Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal PolypsRecruitingNCT06850805Phase 31 country
- Neural Dissimilarity in Patients With Chronic Rhinosinusitis With Nasal Polyps Treated With BiologicsNot yet recruitingNCT078191621 country
- Mepolizumab and in Office-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS).RecruitingNCT07814924Phase 41 country
- CRS Questionnaire Validation ProjectRecruitingNCT0697097711 countries
- Efficacy and Safety of Depemokimab Monotherapy Without Concomitant Use of Intranasal Corticosteroids (INCS) in Japanese Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)RecruitingNCT07701967Phase 41 country
- China CRSwNP Registry StudyNot yet recruitingNCT077956581 country
- Effect of Post Operative Low Dose Oral Azithromycin in Chronic Rhinosinusitis Patients With Nasal PolypsNot yet recruitingNCT07780292Phase 4
- Active vs. Passive VR During Office-based ENT ProceduresNot yet recruitingNCT07599826Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of AK139 in Participants With Chronic Rhinosinusitis With Nasal PolypsNot yet recruitingNCT07755371Phase 21 country
- Triamcinolone Nanocapsules After Endoscopic Nasal SurgeryRecruitingNCT07714525Phase 21 country
- A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With or Without Comorbid AsthmaRecruitingNCT07436949Phase 1/21 country
- Study on Drug Interactions Affecting the Pharmacokinetics of RSS0343 TabletNot yet recruitingNCT07696091Phase 11 country
- Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell TrainingRecruitingNCT07681973Not applicable1 country
- Evaluation of the Safety and Performance of a Bioresorbable Nasal Dressing Containing Mometasone Furoate (MF)Enrolling by invitationNCT07286201Not applicable1 country
- Preoperative Stapokibart for Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Nasal PolypsNot yet recruitingNCT07616609Not applicable1 country
- 3D Printing to Improve Nasal Irrigation OutcomeRecruitingNCT06118554Not applicable1 country
- BIOlogics in Severe Nasal POlyposis SurvEy.: a French RegistryRecruitingNCT06501807Not applicable1 country
- Polysomnographic Findings in Nasal PolyposisRecruitingNCT03725956Not applicable1 country
- Xylitol vs Saline Nasal Irrigations in CF-CRSEnrolling by invitationNCT05531630Not applicable1 country
- Upper Airway Inflammation and Olfaction: Mechanisms of Loss and RecoveryRecruitingNCT06776042Not applicable1 country
- Inflammatory Profiles, Histopathological Features, and Remodeling Factors in Chronic Rhinosinusitis With Nasal PolypsNot yet recruitingNCT07528820Not applicable1 country
- Phenotyping of Type 2 Inflammation Profile by Rheology of Nasal Secretions and Tissue Quantification of Eosinophilic Polymorphonuclear Cells in the Middle TurbinateNot yet recruitingNCT07524127Not applicable1 country
- Follow-up of Spanish Prospective Asthma and Nasal Polyposis RegistryRecruitingNCT061638071 country
- Efficacy and Safety of Fully Resorbable Sinus Drug-eluting Stents in Patients With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps After Surgery: A Prospective, Randomized Controlled TrialRecruitingNCT07498374Not applicable1 country
- A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of CM326 in Participants With Chronic Rhinosinusitis With Nasal PolyposisNot yet recruitingNCT07420257Phase 3
- A Study to Evaluate the Efficacy and Safety of LP-003 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)Not yet recruitingNCT07313917Phase 21 country
- In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal PolypsRecruitingNCT02975310Not applicable1 country
- Real-Time Diagnosis of Eosinophilic Nasal Polyps Using High-Sensitivity SpectroscopyRecruitingNCT07125586Not applicable1 country
- Complete Remission After Treatment With Biologics for Nasal PolypsRecruitingNCT07268313Phase 41 country
- Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal PolypsRecruitingNCT07245329Not applicable1 country
- Efficacy and Safety of SHR-1905 Injection in Subjects With Chronic Rhinosinusitis With Nasal PolypsRecruitingNCT07132827Phase 31 country
- Tapering of Biologics in Chronic Rhinosinusitis With Nasal PolypsRecruitingNCT07187583Phase 41 country
- Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis (CRS).RecruitingNCT07184684Phase 2/31 country
- A Study to Evaluate the Efficacy and Safety of HTMC0658 Tablets in the Treatment of Chronic Rhinosinusitis Without Nasal PolypsRecruitingNCT07174115Phase 21 country
- The German National CRS Registry (GenreCRS): Clinical Evaluation of the New European Academy for Allergy and Clinical Immunology (EAACI) Criteria for CRSwNP Disease Control, Remission and Cure in a Real-World Evidence Study ApproachNot yet recruitingNCT06815211
- Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNPRecruitingNCT063988731 country
- Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal PolypsRecruitingNCT05009758Not applicable1 country
- Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNPRecruitingNCT05094570Phase 41 country
- A Cohort Study on Biomarkers to Predict the Efficacy of Biologics for Chronic Rhinosinusitis with Nasal PolypsNot yet recruitingNCT06801353Phase 41 country