Drug
Cobicistat clinical trials
Also written Tybost and GS-9350.
- studies test it
- 59
- open now
- 4
- in phase 3
- 21
- first study started
- 2009
Keep track of what changes. Save the Cobicistat studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
59 studies that test it; most in 2015 (12)
| Year | Studies |
|---|---|
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 3 |
| 2012 | 2 |
| 2013 | 7 |
| 2014 | 6 |
| 2015 | 12 |
| 2016 | 3 |
| 2017 | 4 |
| 2018 | 1 |
| 2019 | 1 |
| 2020 | 5 |
| 2021 | 3 |
| 2022 | 4 |
| 2023 | 1 |
| 2024 | 4 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 23
- Phase 2
- 6
- Phase 3
- 21
- Phase 4
- 9
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 40 · Other 19
Gilead Sciences (22) · Bristol-Myers Squibb (4) · Janssen Sciences Ireland UC (3) · Janssen Research & Development, LLC (3) · National Institutes of Health Clinical Center (CC) (2) · Fore Biotherapeutics (1) · Janssen Scientific Affairs, LLC (1) · The Crofoot Research Center, Inc. (1)
Often tested with
Tested in the same studies.
Emtricitabine (30) · Tenofovir alafenamide (27) · Darunavir (22) · Elvitegravir (22) · Atazanavir (9) · Emtricitabine tenofovir alafenamide (5) · Ritonavir (5) · Cobicistat mixture with darunavir (2)
Studies
Open first, then newest update. How each study uses Cobicistat is read from its arms, and is right about nine times in ten.
Testing it · 59
- A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV TreatmentsRecruitingPhase 4Gilead SciencesNCT06337032Written as E/C/F/TAF
- A Trial to Assess Cobicistat Boosted Venetoclax in Combination With Azacitidine in Adult Patients With Newly Diagnosed AMLRecruitingPhase 2Stichting Hemato-Oncologie voor Volwassenen NederlandNCT06014489Written as Cobicistat
- Effectiveness and Safety of Darunavir/Cobicistat Plus Lamivudine Compared With Darunavir/Cobicistat Plus Tenofovir Alafenamide/Emtricitabine in Virologically Suppressed People Living With HIV at 24 and 48 Weeks of Follow-upRecruitingPhase 4Instituto Mexicano del Seguro SocialNCT07678268Written as Dual therapy: darunavir/cobicistat + lamivudine
- Improving Osimertinib Exposure and Cost-effectiveness Using Pharmacokinetic Boosting With CobicistatRecruitingPhase 4Maastricht University Medical CenterNCT05748093Written as Cobicistat
- Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIVActive, not recruitingPhase 2/3Gilead SciencesNCT02016924Written as Cobicistat
- A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Participants.CompletedPhase 1Fore BiotherapeuticsNCT06385119Written as Cobicistat
- Cost-effectiveness of Different Antiretroviral Treatment in Patients HIV NaiveWithdrawnPhase 4Juan A. ArnaizNCT02470650Written as elvitegravir/cobicistat/emtricitabine/tenofovir
- A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients with Advanced Stage or Metastatic Pancreatic Ductal AdenocarcinomaTerminatedPhase 1German Cancer Research CenterNCT05494866Written as Cobicistat Oral Tablet
- A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy ParticipantsCompletedPhase 1Janssen Sciences Ireland UCNCT02578550Written as Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide fixed-dose combination (FDC)
- Study to Evaluate the Relative Bioavailability of Fixed-dose Combination Tablet Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) as a Whole Tablet, as a Split Tablet, and as Crushed Tablet in Healthy Adult ParticipantsCompletedPhase 1Janssen Scientific Affairs, LLCNCT02984852Written as Cobicistat (COBI)
- A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat as Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared With Co-administration of the Separate AgentsCompletedPhase 1Janssen Research & Development, LLCNCT04661397Written as Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide FDC
- A Study of Darunavir in the Presence of Cobicistat When Administered as a Fixed Dose Combination Under Fed ConditionsCompletedPhase 1Janssen Research & Development, LLCNCT04718805Written as Cobicistat
- Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART)CompletedPhase 4The Crofoot Research Center, Inc.NCT04388904Written as Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (FDC)
- Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health VolunteersCompletedPhase 1National Institutes of Health Clinical Center (CC)NCT03864406Written as Cobicistat
- Electrophysiological Effects of Potential QT Prolonging DrugsCompletedPhase 1Food and Drug Administration (FDA)NCT05716854Written as Cobicistat
- A Study of PBI-200 With Ritonavir or Cobicistat in Healthy VolunteersCompletedPhase 1Pyramid BiosciencesNCT05692570Written as Cobicistat Oral Tablet
- A Study to Compare the Drug Levels of Atazanavir and Cobicistat Between the Coadministration of Age-Appropriate Mini-Tablet Formulations and the Coadministration of the Individual Reference Products in Healthy Adults Under Fed ConditionsCompletedPhase 1Bristol-Myers SquibbNCT05236738Written as Cobicistat
- A Study of Darunavir in the Presence of Cobicistat When Administered as a Fixed Dose Combination Compared to the Co-administration of the Separate Available Formulations of Darunavir and Cobicistat Under Fed Conditions in Healthy ParticipantsCompletedPhase 1Janssen Research & Development, LLCNCT05378906Written as COBI
- A Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed Dose Combination (FDC) Versus a Regimen Consisting of Darunavir/Cobicistat FDC With Emtricitabine/Tenofovir Disoproxil Fumarate FDC in Treatment-naive HIV Type 1 Infected SubjectsCompletedPhase 3Janssen Sciences Ireland UCNCT02431247Written as Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide FDC
- Pharmacokinetic Boosting of OsimertinibCompletedEarly Phase 1Academisch Ziekenhuis MaastrichtNCT03858491Written as Cobicistat
See all 59 studies that test Cobicistat →
Given in every arm · 8 — Cobicistat is usual care beside what is tested
- A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 MutationRecruitingPhase 1/2Syndax PharmaceuticalsNCT04065399Written as cobicistat
- Pharmacokinetic Boosting of Olaparib to Improve Exposure, Tolerance and Cost-effectivenessRecruitingPhase 4Radboud University Medical CenterNCT05078671Written as Cobicistat
- KF2024#1-trial: Esketamine Interaction StudyCompletedPhase 1Helsinki University Central HospitalNCT06726382Written as Cobicistat 150 MG
- Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents and Virologically Suppressed ChildrenCompletedPhase 2/3Gilead SciencesNCT01854775Written as E/C/F/TAF
- ProSTAR: A Study Evaluating CPI-1205 in Patients With Metastatic Castration Resistant Prostate CancerCompletedPhase 1/2Constellation PharmaceuticalsNCT03480646Written as Cobicistat
- Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus LevelsTerminatedPhase 1Gilead SciencesNCT05458102Written as Cobicistat
- Safety and Efficacy of E/C/F/TDF Versus RTV-Boosted ATV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment-Naive WomenCompletedPhase 3Gilead SciencesNCT01705574Written as E/C/F/TAF
- First-in-Human Study of an Oral Plasmodium Falciparum Plasma Membrane Protein InhibitorCompletedPhase 1St. Jude Children's Research HospitalNCT02661373Written as Cobicistat
As the comparator · 1 — what is tested is compared with Cobicistat
Codes
What other systems call Cobicistat · ClinicalTrials.gg INT006607
- MeSH (NLM) D000069547CobicistatConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) LW2E03M5PGCOBICISTATConfirmed FDA, NLM, Wikidata
- RxNorm 1306284Confirmed FDA, Wikidata
- Wikidata Q5138908cobicistatConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C97360CobicistatOne source FDA
- DrugBank DB09065One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069547 | Cobicistat | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | LW2E03M5PG | COBICISTAT | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1306284 | — | Confirmed FDA, Wikidata |
| Wikidata | Q5138908 | cobicistat | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C97360 | Cobicistat | One source FDA |
| DrugBank | DB09065 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.