Dysphonia clinical trials
The registry lists 132 studies for Dysphonia across more than 10 countries. 38 are recruiting or about to start. 98 of them are mainly about Dysphonia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (8) · University of Minnesota (6) · Kristina Simonyan (5) · Massachusetts Eye and Ear Infirmary (5) · NYU Langone Health (4) · University of California, San Francisco (3) · University of British Columbia (3) · University of Southern California (3)
What is being tested here
Drugs under test in Dysphonia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Apr 2027Translaryngeal Vibration for Hyperfunctional Voice Disorders · Phase 3 · Texas Christian University
- Nov 2026Assessment of the Efficacy of a Highly Standardized Ginger and Perilla Nutraceutical (Dispepril®) in Improving Gastric and Intestinal Symptoms in Patients With Functional Dyspepsia · Liaquat University of Medical & Health Sciences
- Dec 2026tDCS for Laryngeal Dystonia · Yale University
- Dec 2026Autonomic Dysfunction in Functional Dysphonia · University Ghent
- Dec 2026Improving Voice Production for Adults With Age-related Dysphonia · University of Arizona
- Dec 2026Effects of Neuromodulation in Laryngeal Dystonia · MGH Institute of Health Professions
- Dec 2026Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery · Seoul National University Hospital
- Feb 2027Monitoring of the Safety and the Performance of the Endoscopic Cap Electrode (ECE50) · MED-EL Elektromedizinische Geräte GesmbH
- Feb 2027Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia · University of Minnesota
- Jun 2027Active vs. Passive VR During Office-based ENT Procedures · Cedars-Sinai Medical Center
Who these studies take
Of the 25 Dysphonia studies recruiting now, 8 (32%) set no upper age limit and 9 (36%) stop at 75 or younger. 7 (28%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 14 (56%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (16%) | 4 (16%) |
| 18 | 21 (84%) | 21 (84%) |
| 30 | 24 (96%) | 24 (96%) |
| 40 | 24 (96%) | 24 (96%) |
| 50 | 24 (96%) | 24 (96%) |
| 65 | 22 (88%) | 22 (88%) |
| 75 | 17 (68%) | 17 (68%) |
| 85 | 10 (40%) | 10 (40%) |
Across all 132 studies, recruiting or not: 30% stop at 75 or younger and 20% at 65; 16% take children; 4% are for women only and 2% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Dysphonia studies take
Of 44 interventional studies with no phase under Dysphonia, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 26 mo11–47 · 44 studies | — | 26 mo11–47 · 44 studies |
| Observational | 26 mo12–193 · 18 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Stopped1
- Assessment of Laryngopharyngeal Sensation: Cancer Survivor CohortSuspendedNov 5, 2026NCT06078527
Newly registered1
- EMG-Guided Versus Endoscopic-Catheter Botulinum Toxin Injection for Spasmodic DysphoniaOct 26, 2026NCT07894172
Studies
Recruiting first, then most recently updated. Showing 50 of 132. Browse all 132 → or search them.
- EMG-Guided Versus Endoscopic-Catheter Botulinum Toxin Injection for Spasmodic DysphoniaNot yet recruitingNCT07894172Not applicable
- Active vs. Passive VR During Office-based ENT ProceduresNot yet recruitingNCT07599826Not applicable1 country
- Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal ApplicationRecruitingNCT055060851 country
- Capturing Key MG-symptoms Using Smartphone Recordings.RecruitingNCT067434901 country
- Transcranial Magnetic Stimulation in Laryngeal DystoniaNot yet recruitingNCT07683767Not applicable
- Assessment of the Efficacy of a Highly Standardized Ginger and Perilla Nutraceutical (Dispepril®) in Improving Gastric and Intestinal Symptoms in Patients With Functional DyspepsiaNot yet recruitingNCT07655219Not applicable1 country
- Usefulness and Feasibility of Ultrasound in Office Laryngology ProceduresNot yet recruitingNCT06579989Not applicable1 country
- A Personalized Voice Restoration Device for Patients With LaryngectomyNot yet recruitingNCT05479643Not applicable1 country
- Voice Therapy Per the Rehabilitation Treatment Specification SystemRecruitingNCT06152627Not applicable1 country
- Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice TremorNot yet recruitingNCT07041203Phase 11 country
- Brain Network Changes After Vibro-tactile Stimulation in Laryngeal DystoniaRecruitingNCT07443891Not applicable1 country
- Effects of Neuromodulation in Laryngeal DystoniaRecruitingNCT05095740Not applicable1 country
- tDCS for Laryngeal DystoniaRecruitingNCT06830174Not applicable1 country
- PhoRTE® Therapy Efficacy: In-Person Versus TelehealthNot yet recruitingNCT06934265Not applicable1 country
- Brain Networks in DystoniaRecruitingNCT030429621 country
- Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice TremorRecruitingNCT051501061 country
- Brain-Computer Interfaces in Laryngeal DystoniaRecruitingNCT04421365Not applicable1 country
- Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated DystoniaRecruitingNCT05317390Not applicable1 country
- Imaging Genetics of Laryngeal DystoniaRecruitingNCT030429751 country
- Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice TremorRecruitingNCT05216770Early Phase 11 country
- Deep Brain Stimulation in Laryngeal Dystonia and Voice TremorRecruitingNCT05150093Not applicable1 country
- Deconstructing Voice Therapy: Towards Enhanced Communication OutcomesRecruitingNCT07176988Not applicable1 country
- Translaryngeal Vibration for Hyperfunctional Voice DisordersRecruitingNCT07145086Phase 31 country
- The Mechanism Versus PPI TrialRecruitingNCT06999577Phase 41 country
- Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid SurgeryRecruitingNCT06002984Not applicable1 country
- Management of Non-Organic Dysphonia in Adults.RecruitingNCT06856785Not applicable1 country
- Characterization of "Bamboo" and Other Vocal Cord Lesions Responsible for Dysphonia in Patients With Systemic Autoimmune Diseases (BAMBOO)RecruitingNCT067797991 country
- Longitudinal Non-invasive Analysis of VOCAle Cord Function Based on Trans-laryngeal Ultrasound Acquisitions and Voice RecordingsNot yet recruitingNCT06776393Not applicable
- Dynamics of Pelvic Floor Muscles With Different Phonation Patterns Among Female StudentsNot yet recruitingNCT067162681 country
- The Use of Dexamethasone in Total Thyroidectomy to Improve Voice Outcome and HypocalcaemiaRecruitingNCT05732883Phase 21 country
- The 'Lombard Effect' in Patients Affected by Adductor Laryngeal DystoniaNot yet recruitingNCT06402214Not applicable1 country
- Investigation of the Effectiveness of Group Voice Therapy in ChildrenRecruitingNCT06124053Not applicable1 country
- Autonomic Dysfunction in Functional DysphoniaRecruitingNCT06100601Not applicable1 country
- Voice Analysis in Women With Polycystic Ovary SyndromeNot yet recruitingNCT06085170
- Cortical Silent Period in Laryngeal DystoniaRecruitingNCT055803021 country
- Impact of Temporomandibular Joint Dysfunction on Objective and Subjective Vocal MeasuresRecruitingNCT060465211 country
- Artificial Intelligence and Benign Lesions of Vocal Folds RecognitionRecruitingNCT057546061 country
- A Phase 2 Trial of Deep Brain Stimulation for Spasmodic DysphoniaNot yet recruitingNCT04938154Phase 21 country
- Dysphagia and Dysphonia in Anterior Cervical Spinal SurgeryCompletedNCT07713693Not applicable1 country
- Assessment of Laryngopharyngeal Sensation: Cancer Survivor CohortSuspendedNCT060785271 country
- Spasmodic Dysphonia InterviewsCompletedNCT065613341 country
- Zinc Supplementation Prior to Botox Injections for Spasmodic DysphoniaCompletedNCT05892770Phase 1/21 country
- Usability of Vibro-tactile Stimulation to Treat Spasmodic DysphoniaCompletedNCT06111027Phase 1/21 country
- Voice Rest Versus Hypofunctional Whispering After PhonosurgeryCompletedNCT07704125Not applicable1 country
- DaxibotulinumtoxinA Injection for Treatment of Adductor Spasmodic DysphoniaCompletedNCT05158166Phase 1/21 country
- Dysphonia Pain Perception Following Botulinum Toxin InjectionsCompletedNCT06767215Not applicable1 country
- Stabilization Training, Voice And Neck PainCompletedNCT07401576Not applicable1 country
- A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold ScarringCompletedNCT04290182Phase 1/21 country
- Voice and Swallowing Outcomes Following Revision Anterior Cervical Spine SurgeryCompletedNCT010170551 country
- Monitoring of the Safety and the Performance of the Endoscopic Cap Electrode (ECE50)Active, not recruitingNCT052459421 country