Omega-3 fatty acid clinical trials
Also written Omega-3.
A group of medicines. Docosahexaenoic Acids (80 studies), Omacor (78 studies), Eicosapentaenoic Acid (56 studies) and others are counted on their own pages; this page counts the studies that name Omega-3 fatty acid itself.
Counted the way a researcher would: Omega-3 fatty acid with its salts, dosage forms, brands and biosimilars. Looking for a trial to join? Including related medicines shows more you could take part in.
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How each study uses omega-3 fatty acid is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the omega-3 fatty acid studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your alerts, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorizations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Medicines filed under Omega-3 fatty acid
As reviewed, so not every one. Each counts its studies on its own page, not here.
Studies by the year they started
376 studies that test it; most in 2014 (26); 1 more planned to start later
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1997 | 1 |
| 2000 | 1 |
| 2002 | 1 |
| 2003 | 3 |
| 2004 | 10 |
| 2005 | 9 |
| 2006 | 5 |
| 2007 | 11 |
| 2008 | 22 |
| 2009 | 22 |
| 2010 | 23 |
| 2011 | 23 |
| 2012 | 24 |
| 2013 | 23 |
| 2014 | 26 |
| 2015 | 19 |
| 2016 | 17 |
| 2017 | 16 |
| 2018 | 19 |
| 2019 | 17 |
| 2020 | 14 |
| 2021 | 8 |
| 2022 | 9 |
| 2023 | 19 |
| 2024 | 8 |
| 2025 | 13 |
| 2026 | 12 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 18 · Other 360
Brigham and Women's Hospital (16) · Tehran University of Medical Sciences (7) · Massachusetts General Hospital (6) · China Medical University Hospital (6) · Mayo Clinic (6) · Coordinación de Investigación en Salud, Mexico (5) · Ain Shams University (4) · Université de Sherbrooke (4)
Often tested with
Tested in the same studies.
Cholecalciferol (19) · Vitamin D (7) · Aspirin (5) · Curcumin (5) · Vitamin E (4) · Atorvastatin (4) · Cholestyramine Resin (4) · Fenofibrate (4)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 18, 2 in phase 3
Studies that test omega-3 fatty acid, phase 3 first.
- Dec 2026Efficiency of a Composite Personalised Care on Functional Outcome in Early PsychosisPhase 3 · Centre Hospitalier St Anne
- Oct 2027VITAL Rhythm StudyPhase 3 · Brigham and Women's Hospital
- Nov 2026Effectiveness of Neuroplasticity-Targeted Supplements on Neuroinflammatory Markers, ADHD Symptom Severity, and Clinical Scores in ChildrenNot applicable · Khyber Medical University Peshawar
- Dec 2026Regenerative Root Canal Treatment of Immature Teeth Using Omega-3 Fatty AcidsNot applicable · Mansoura University
- Dec 2026Effects of Vitamin D and Omega-3 Fatty Acids on Infectious Diseases and hCAP18 (VITAL Infection)Not applicable · Brigham and Women's Hospital
- Dec 2026Free Fatty Acid Effects In Type 2 DiabetesNot applicable · University of Ulster
- Dec 2026Omega-3 Fatty Acids and Nutritional Support in Gastrointestinal CancerNot applicable · Maimónides Biomedical Research Institute of Córdoba
- Jan 2027Effects of Omega-3 and Whey Protein Supplementation on Lean Mass in Older AdultsNot applicable · Federal University of Uberlandia
- Feb 2027Fish Oil and HDL Function in Patients on Maintenance HemodialysisNot applicable · Medical University of Vienna
- Feb 2027Omega 3 Fatty Acids and ERPR(-)HER2(+/-) Breast Cancer PreventionNot applicable · City of Hope Medical Center
Studies
Open first, then newest update. How each study uses omega-3 fatty acid is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 378
- Toripalimab, Induction Chemotherapy, Radiation Therapy With Omega-3 for Locally Advanced Nasopharyngeal CarcinomaRecruitingPhase 2Affiliated Hospital of Guangdong Medical UniversityNCT07136519Written as Omega-3
- NMDA Enhancement Combined With Omega-3 for Early DementiaNot yet recruitingPhase 2Chang Gung Memorial HospitalNCT05181189Written as DAOIB+Omega-3
- A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)RecruitingNot applicableMemorial Sloan Kettering Cancer CenterNCT06055894Written as Omega-3
- Supplementation Absorption ComparisonRecruitingPhase 4RDC Clinical Pty LtdNCT07791797Written as Aquacelle® Omega 3
- Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory TrialRecruitingPhase 2North-West University, South AfricaNCT07118059Written as Omega-3 (EPA+DHA)
- Effect of Fish Oil Supplementation on the Voice of Female Professional Voice Users (PVU)Not yet recruitingNot applicableBaylor UniversityNCT07800702Written as Omega-3 Polyunsaturated Fatty Acids
- Free Fatty Acid Effects In Type 2 DiabetesEnrolling by invitationNot applicableUniversity of UlsterNCT07677995Written as Omega-3 Fatty Acids
- Fish Oil and HDL Function in Patients on Maintenance HemodialysisNot yet recruitingNot applicableMedical University of ViennaNCT07730385Written as n-3 PUFA (fish oil)
- Omega-3 Supplementation in Systemic Lupus ErythematosusNot yet recruitingNot applicableUniversity of Sao PauloNCT07393399Written as Omega-3 Fatty Acids (EPA plus DHA)
- Impact of an Optimized Omega-3 Formulation on Inflammation and Endothelial Dysfunction in Pulmonary Arterial HypertensionNot yet recruitingNot applicableUniversity Hospital, Strasbourg, FranceNCT07697235Written as OMega 3
- Omega-3 Plus Low-Dose Aspirin in Smokers With Stage III PeriodontitisRecruitingNot applicableAl-Azhar UniversityNCT07673185Written as Omega-3 Fatty Acids (EPA plus DHA) plus low dose aspirin
- Effectiveness of Neuroplasticity-Targeted Supplements on Neuroinflammatory Markers, ADHD Symptom Severity, and Clinical Scores in ChildrenRecruitingNot applicableKhyber Medical University PeshawarNCT07665658Written as Omega-3 Fatty Acids
- Phase II, Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Omega-3 Fatty Acids as an Adjunct to Morphine in Acute Postoperative PainNot yet recruitingPhase 2National University of La RiojaNCT07657468Written as Omega-3 fatty acids + Morphine group
- Effects of Omega-3 Fatty Acids on Inflammation and Gut Microbiota in Celiac DiseaseRecruitingNot applicableUniversity of ChileNCT07585669Written as n-3 Polyunsaturated Fatty Acids (PUFAs)
- Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.Not yet recruitingNot applicableNicosia General HospitalNCT06995586Written as Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose
- Omega-3 Fatty Acids and Subconcussive Head ImpactsRecruitingNot applicableIndiana UniversityNCT06736925Written as Omega-3 Fatty Acids (EPA plus DHA)
- Efficiency of a Composite Personalised Care on Functional Outcome in Early PsychosisRecruitingPhase 3Centre Hospitalier St AnneNCT05796401Written as Personalized neuroprotective strategies : Vitamin B12, folinic acid, Omega 3, NAC
- Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty AcidsRecruitingNot applicableInstitut de Recherches Cliniques de MontrealNCT04485871Written as Omega-3 fatty acids
- Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological RecoveryNot yet recruitingNot applicableSt. Mary's University, TwickenhamNCT07439601Written as Oil Supplementation
- Omega-3 Fatty Acids, Inflammation, Gut Microbiota in Youth With DepressionRecruitingNot applicableChina Medical University HospitalNCT07363551Written as Omega-3 fatty acids
See all 378 studies that test omega-3 fatty acid →
Given beside what is tested · 4 — omega-3 fatty acid is usual care or a partner of the new treatment
- Omega 3 Plus Vaginal Progesterone on Birth Weight of Constitutionally Small for Gestational Age FetusesCompletedNot applicableAssiut UniversityNCT04161989Written as omega-3 fatty acids
- TEFA Family Prevention: Glutenfree Diet to Preserve Beta-cell FunctionStatus unknownNot applicableLund UniversityNCT02605148Written as Omega 3 fatty acid
- Omega 3 FA Supplements as Augmentation in the Treatment of DepressionTerminatedPhase 2/3UConn HealthNCT01803711Written as Omega 3 Fatty acids
- Multimodal Therapeutic Approach in Undernourished Maintenance Hemodialysis Patients (AMERICANO)Status unknownPhase 3University Hospital, Clermont-FerrandNCT02418065Written as n3 polyunsaturated fatty acid
As the comparator · 4 — what is tested is compared with omega-3 fatty acid
- Physiological Effects of Nutritional Support in Patients With Parkinson's DiseaseCompletedNot applicableThomas Jefferson UniversityNCT02445651Written as Oral Supplements: Baicalin, Ganoderma, Omega 3 and Curcumin
- Chia Seeds Consumption in HypertriglyceridemiaCompletedNot applicableShahid Beheshti UniversityNCT06020950Written as Omega-3 supplementation
- Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)CompletedPhase 4SanofiNCT02642159Written as Omega-3 fatty acids
- Omega-3 Supplementation in HIV Patients With Therapeutic Lifestyle Change Diet.CompletedPhase 3Instituto Mexicano del Seguro SocialNCT02537236Written as Omega-3 fatty acids
What changed recently
From the registry's own updates since Oct 16, 2026.
Started recruiting1
Codes
What other systems call omega-3 fatty acid · ClinicalTrials.gg INT008472
- UNII (FDA) 71M78END5SOMEGA-3 FATTY ACIDSConfirmed FDA, Wikidata
- RxNorm 4301One source FDA
- Wikidata Q191756omega-3 fatty acidConfirmed FDA, Wikidata
- NCI Thesaurus C493Omega-3 Fatty AcidOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | 71M78END5S | OMEGA-3 FATTY ACIDS | Confirmed FDA, Wikidata |
| RxNorm | 4301 | — | One source FDA |
| Wikidata | Q191756 | omega-3 fatty acid | Confirmed FDA, Wikidata |
| NCI Thesaurus | C493 | Omega-3 Fatty Acid | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.