Lacerations clinical trials
The registry lists 174 studies for Lacerations across more than 10 countries. 43 are recruiting or about to start. 119 of them are mainly about Lacerations (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
Hacettepe University (4) · Children's Hospitals and Clinics of Minnesota (2) · Zhongshan Ophthalmic Center, Sun Yat-sen University (2) · Lille Catholic University (2) · Temple University (2) · University of California, Irvine (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2) · Baylor College of Medicine (2)
What is being tested here
Drugs under test in Lacerations studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Capsaicin | 1 | 0 | 1 |
| Ropivacaine | 1 | 0 | 1 |
| Varenicline | 1 | 0 | 1 |
| Midazolam | 0 | 0 | 2 |
| Lidocaine | 0 | 0 | 2 |
| Cephalexin | 0 | 0 | 2 |
| Intranasal Ketamine | 0 | 0 | 2 |
| Nitrous Oxide | 0 | 0 | 2 |
| Botulinum toxin type A | 0 | 0 | 2 |
| Dexmedetomidine | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jan 2027ACB vs no Block for Pediatric ACL Reconstruction · Phase 3 · Isabella Jaramillo
- Jun 2027Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs · Phase 3 · Florida Atlantic University
- Nov 2026Prospective Study Comparing Two Classification Systems for Second-degree Vaginal Tears During Spontaneous Childbirth to Assess Their Ability to Predict Postpartum Complications. · University of Campania Luigi Vanvitelli
- Dec 2026Augmented Reality in Surgery · I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
- Dec 2026Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment · University of California, Berkeley
- Jan 2027Prospective Cohort Study of Villarreal CF Youth Players · Cardenal Herrera University
- Jan 2027Clinical Analysis of a Novel Flexor Tendon Repair Technique · Brett Lewellyn
- Jan 2027OJO-miR: microRNA Expression in Allergic Conjunctivitis. · Instituto de Oftalmología Fundación Conde de Valenciana
- Feb 2027Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment · Zhongshan Ophthalmic Center, Sun Yat-sen University
- Jun 2027Will a Hands on Technique Applied to the Face Increase the Tear Production in Participants · Edward Via Virginia College of Osteopathic Medicine
Who these studies take
Of the 27 Lacerations studies recruiting now, 15 (56%) set no upper age limit and 10 (37%) stop at 75 or younger. 6 (22%) take children under 18. 6 (22%) are for women only and 0 (0%) for men only; 9 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (15%) | 4 (15%) |
| 18 | 24 (89%) | 18 (67%) |
| 30 | 24 (89%) | 18 (67%) |
| 40 | 25 (93%) | 19 (70%) |
| 50 | 21 (78%) | 16 (59%) |
| 65 | 20 (74%) | 16 (59%) |
| 75 | 17 (63%) | 13 (48%) |
| 85 | 17 (63%) | 13 (48%) |
Across all 174 studies, recruiting or not: 52% stop at 75 or younger and 47% at 65; 34% take children; 19% are for women only and 1% for men only; 35% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lacerations studies take
Of 50 interventional studies with no phase under Lacerations, half reached primary completion within 19 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 19 mo12–72 · 50 studies | — | 19 mo10–72 · 46 studies |
| Observational | 25 mo12–35 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Newly registered1
- Arthrocentesis vs Observation Study for Acute ACL TearsNov 10, 2026NCT07929922
Studies
Recruiting first, then most recently updated. Showing 50 of 174. Browse all 174 → or search them.
- Arthrocentesis vs Observation Study for Acute ACL TearsRecruitingNCT07929922Not applicable1 country
- Identification of Diagnosis Biomarkers in the Tears of Alzheimer's Disease Patients: The COG-EYE Pilot StudyRecruitingNCT06661564Not applicable1 country
- Inflammatory Mediators of Glaucoma After Corneal Transplantation (AH-Tears)RecruitingNCT04339907Not applicable1 country
- Bone-Patellar Tendon-Bone Versus Quadriceps Tendon Autograft for Anterior Cruciate Ligament Reconstruction: A Non-Inferiority Trial Regarding Anterior Knee PainNot yet recruitingNCT07846709Not applicable
- The Effect of Osteopathic Manipulative Techniques on Human Tear CompositionEnrolling by invitationNCT07633496Not applicable1 country
- Clinical and Functional Outcomes After ACL Reconstruction Versus Primary RepairRecruitingNCT073182721 country
- Nailbed Repair for Patients With Nailbed InjuriesRecruitingNCT07388823Not applicable1 country
- Tear Biomarkers for MigraineNot yet recruitingNCT07690696
- Measuring Knee Laxity and Pivot Shift in ACL-Deficient PatientsNot yet recruitingNCT076889671 country
- Prospective Cohort Study of Villarreal CF Youth PlayersNot yet recruitingNCT076536331 country
- Augmented Reality in SurgeryRecruitingNCT076362781 country
- Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye TreatmentRecruitingNCT07606625Phase 41 country
- Prospective Study Comparing Two Classification Systems for Second-degree Vaginal Tears During Spontaneous Childbirth to Assess Their Ability to Predict Postpartum Complications.RecruitingNCT071246761 country
- Evaluation of Survival and Clinical Outcomes of Patients Treated With Isolated All-inside Meniscal Sutures or With Meniscal Sutures Associated With Ligament ReconstructionRecruitingNCT072894121 country
- Study on Fewer Tears (SOFT) - The Effect of Local Anesthesia on the Incidence of Perineal Tears in the First Vaginal BirthEnrolling by invitationNCT074997521 country
- Effects of a Preoperative Cognitive-Behavioral Intervention on Kinesiophobia and Function in Anterior Cruciate Ligament ReconstructionRecruitingNCT07423767Not applicable1 country
- Pain Biomarker StudyEnrolling by invitationNCT03511846Phase 11 country
- Patient Satisfaction and Cosmetic Outcomes in Adhesive Strip Versus Suture Repair for Simple Facial LacerationsNot yet recruitingNCT06550999Not applicable1 country
- Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration RepairsRecruitingNCT06910241Phase 31 country
- Physiotherapeutic Protocol Compared to Usual Care in the Treatment of Primiparas After Perineal TraumaRecruitingNCT07170007Not applicable1 country
- ACB vs no Block for Pediatric ACL ReconstructionRecruitingNCT06875427Phase 31 country
- Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric PopulationNot yet recruitingNCT06559137Phase 21 country
- Perineal Massage During Labor for the Prevention of Perineal TraumaRecruitingNCT07099690Not applicable1 country
- Clinical Analysis of a Novel Flexor Tendon Repair TechniqueRecruitingNCT070688801 country
- Anxiolysis for Laceration Repair in ChildrenRecruitingNCT05383495Phase 31 country
- The Effect of Birth Ball and Perineal Massage on Perineal Pain, Perineal Trauma and Birth SatisfactionNot yet recruitingNCT06935643Not applicable
- Wear and Tear on Military Personnel Post Caledonian CrisisRecruitingNCT069070301 country
- Slow and Accelerated Rehabilitation ProtocolsRecruitingNCT05450510Not applicable1 country
- Vicryl Rapide Versus Nonabsorbable SutureRecruitingNCT04056013Not applicable1 country
- The Irrigation or No Irrigation in Simple Lacerations TrialsRecruitingNCT02976480Not applicable1 country
- Evaluation of Interventions Based on Behavioral Sciences to Reduce Episiotomy UseNot yet recruitingNCT06625866Not applicable
- TRESPASS Clinical StudyRecruitingNCT06443736Not applicable1 country
- Validation of Human Drugs Target of Repurposed Drugs and Novel TherapiesNot yet recruitingNCT06412718
- Assessment of Tear Production, Corneal Staining, and Comfort Level Wearing Different Types of Contact LensesNot yet recruitingNCT06351410Not applicable1 country
- Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes ResultsRecruitingNCT063682841 country
- Antibiotics for Severe Perineal Laceration to Prevent Infection Following RepairRecruitingNCT04573504Phase 41 country
- Neurological Dry Eye Study Stimulating Both Lacrimal and Vagus NervesNot yet recruitingNCT06271005Not applicable
- Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP TreatmentRecruitingNCT062434971 country
- Outcomes of Massive Rotator Cuff Tendon Tear Treatment.Not yet recruitingNCT06016439Not applicable
- Arthroscopic Repair Versus High Tibial Osteotomy for Medial Meniscus Posterior Root TearsRecruitingNCT05971472Not applicable1 country
- Pattern of Chronic Disease in Adult attendantsabove18years Old in New Vally Elkharga Family Medicine ClinicNot yet recruitingNCT05963373
- Cellular Mechanisms Involved in Muscle PathologyRecruitingNCT057989621 country
- Outcomes Following Pre-marking of Episiotomy LocationRecruitingNCT04719533Not applicable1 country
- Pelvic Floor Training Combined With Perineal Massage Reduces Episiotomy to 5.7%CompletedNCT07626333Not applicable1 country
- Active Noise-Cancelling Headphones With Closed-Loop Communication During Arthroscopic ACL ReconstructionActive, not recruitingNCT07589582Not applicable1 country
- Targeted Deep Pelvic Floor Muscle Physiotherapy Versus Antenatal Perineal Massage in Nulliparous WomenCompletedNCT07764068Not applicable1 country
- Effect of Boric Acid Wet Dressing on Postpartum Perineal Healing and PainCompletedNCT07748182Not applicable1 country
- 3M™ Topical Tissue Adhesive Versus Commercially Available Tissue Adhesive for the Closure of Lacerations and IncisionsTerminatedNCT06217081
- Adductor Canal Block With IPACK Versus 4-in-1 Block for Postoperative Analgesia in Knee SurgeryCompletedNCT07700797Not applicable1 country
- Analysis Of Knee Joint Of Patients With Anterior Cruciate Ligament Injury Undergoing Physiotherapy After Two Different Surgical Techniques: A Randomized Clinical Trial.Active, not recruitingNCT06809920Not applicable1 country