Drug
Metyrapone clinical trials
Also written Metopirone.
- studies test it
- 17
- open now
- 3
- in phase 3
- 2
- first study started
- 1998
Keep track of what changes. Save the Metyrapone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Combined with it in one product
Studies by the year they started
17 studies that test it; most in 2015 (2)
| Year | Studies |
|---|---|
| 1998 | 1 |
| 2001 | 1 |
| 2006 | 1 |
| 2007 | 1 |
| 2011 | 1 |
| 2012 | 1 |
| 2013 | 1 |
| 2015 | 2 |
| 2018 | 1 |
| 2022 | 1 |
| 2023 | 2 |
| 2024 | 1 |
| 2025 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 4
- Phase 2
- 3
- Phase 3
- 2
- Phase 4
- 4
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 4 · Other 13
Eleonora Seelig (3) · Mayo Clinic (2) · Embera NeuroTherapeutics, Inc. (2) · HRA Pharma (1) · University of Michigan (1) · GlaxoSmithKline (1) · Jane Barnes (1) · Universitätsklinikum Hamburg-Eppendorf (1)
Often tested with
Tested in the same studies.
Hydrocortisone (3) · Oxazepam (2) · Dexamethasone (1) · Cosyntropin (1) · Corticorelin ovine (1) · Corticorelin ovine (1) · Alprazolam (1) · NBI 77860 (1)
Studies
Open first, then newest update. How each study uses Metyrapone is read from its arms, and is right about nine times in ten.
Testing it · 17
- Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACSRecruitingPhase 2Mayo ClinicNCT07138274Written as Metyrapone 250 mg Oral Tablets
- Sleep Loss and Circadian Misalignment - Mechanisms of Insulin ResistanceRecruitingPhase 4Washington State UniversityNCT07494084Written as Metyrapone And Hydrocortisone
- Metyrapone Versus Osilodrostat in Patients With Metabolic Autonomous Cortisol Secretion (MACS)RecruitingPhase 4Laikο General Hospital, AthensNCT07268222Written as Metyrapone 250 mg Oral Tablets
- Metyrapone for Mild Autonomous Cortisol Secretion (MACS)Active, not recruitingPhase 2Mayo ClinicNCT06106295Written as Metyrapone
- A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine AddictionCompletedNot applicableEmbera NeuroTherapeutics, Inc.NCT00567814Written as Metyrapone
- Acute Consequences of Glucocorticoid Secretion in Overweight and Obese Individuals During Maximum Calorie IntakeCompletedNot applicableEleonora SeeligNCT06556277Written as Metyrapone And Hydrocortisone
- The Role of Glucocorticoids to Maintain Energy Homeostasis During Starvation (Gluco-Starve)CompletedEarly Phase 1Eleonora SeeligNCT05919992Written as Metyrapone 250 mg Oral Tablets
- Acute Consequences Of Food-induced Glucocorticoid Secretion In Healthy IndividualsCompletedEarly Phase 1Eleonora SeeligNCT05167084Written as Metyrapone 250 mg Oral Tablets
- Effects of Metyrapone in Patients With Endogenous Cushing's SyndromeCompletedPhase 3HRA PharmaNCT02297945Written as metyrapone
- Effects of the Addition of Metyrapone to Antidepressant Therapy in Depression With Dexamethasone Suppression Test Non-suppression.Status unknownPhase 4Centre Hospitalier RouffachNCT03491696Written as Metyrapone
- Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary MeasuresCompletedPhase 1University of MichiganNCT01673087Written as Metyrapone
- To Investigate Effects GSK561679 on Part of the Body's System That Controls the Balance of Many of the Hormones.CompletedPhase 1GlaxoSmithKlineNCT00426608Written as metyrapone
- Cocaine-Metyrapone Interaction Study - 1Status unknownPhase 1National Institute on Drug Abuse (NIDA)NCT00033098Written as Metyrapone
- Single and Multiple Rising Dose Study of Safety and PK of Metyrapone/Oxazepam Combination (EMB-001)CompletedPhase 1Embera NeuroTherapeutics, Inc.NCT02406066Written as metyrapone & oxazepam
- Cortisol and Nutritional Sympathetic ResponsivenessStatus unknownPhase 4Baker Heart Research InstituteNCT01620684Written as metyrapone
- Antiglucocorticoid Augmentation of antiDepressants in DepressionCompletedPhase 3Jane BarnesNCT01375920Written as Metyrapone
- Metyrapone as Additive Treatment in Major DepressionCompletedPhase 2Universitätsklinikum Hamburg-EppendorfNCT00125554Written as Metyrapone
Codes
What other systems call Metyrapone · ClinicalTrials.gg INT007829
- MeSH (NLM) D008797MetyraponeConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) ZS9KD92H6VMETYRAPONEConfirmed FDA, NLM, Wikidata
- RxNorm 6923Confirmed FDA, Wikidata
- Wikidata Q821641metyraponeConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47619MetyraponeOne source FDA
- DrugBank DB01011One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D008797 | Metyrapone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | ZS9KD92H6V | METYRAPONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6923 | — | Confirmed FDA, Wikidata |
| Wikidata | Q821641 | metyrapone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47619 | Metyrapone | One source FDA |
| DrugBank | DB01011 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.