Drug
Mesalamine clinical trials
Also written Mesalazine, Lialda and Asacol.
- studies test it
- 93
- open now
- 7
- in phase 3
- 40
- first study started
- 1999
Keep track of what changes. Save the Mesalamine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Other names
Combined with it in one product
Studies by the year they started
92 studies that test it; most in 2010 (11); 1 more planned to start later
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2000 | 1 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 5 |
| 2004 | 2 |
| 2005 | 7 |
| 2006 | 4 |
| 2007 | 9 |
| 2008 | 7 |
| 2009 | 7 |
| 2010 | 11 |
| 2011 | 6 |
| 2012 | 5 |
| 2013 | 3 |
| 2014 | 3 |
| 2015 | 3 |
| 2016 | 2 |
| 2017 | 3 |
| 2019 | 2 |
| 2022 | 2 |
| 2023 | 2 |
| 2024 | 3 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 17
- Phase 2
- 17
- Phase 3
- 40
- Phase 4
- 18
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 56 · Other 37
Shire (13) · Dr. Falk Pharma GmbH (8) · Warner Chilcott (8) · Ferring Pharmaceuticals (7) · Tillotts Pharma AG (6) · SOFAR S.p.A. (4) · Bausch Health Americas, Inc. (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2)
Often tested with
Tested in the same studies.
Budesonide (2) · Nitazoxanide (1) · Hydrocortisone (1) · Probiotic (1) · Lacticaseibacillus casei (1) · Tetomilast (1) · Tofacitinib (1) · ND-12 (1)
Studies
Open first, then newest update. How each study uses Mesalamine is read from its arms, and is right about nine times in ten.
Testing it · 93
- ASAPP Study - Topical 5-ASA as Prophylaxis for Pouchitis in Ulcerative Colitis Patients After Pelvic Pouch SurgeryNot yet recruitingPhase 4University Hospital, LinkoepingNCT07773948Written as 5-ASA
- ND-12 Combined With H-6 for Adult Chronic Inflammatory DiarrheaRecruitingEarly Phase 1The Second Hospital of Nanjing Medical UniversityNCT07767370Written as mesalazine
- Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo)RecruitingPhase 2AHS Cancer Control AlbertaNCT05663775Written as Mesalamine
- Mesalamine for Colorectal Cancer Prevention Program in Lynch SyndromeRecruitingPhase 2Ann-Sofie BackmanNCT04920149Written as Mesalamine
- TOFACITINIB vs TOFACITINIB WITH MESALAMINE IN ULCERATIVE COLITISNot yet recruitingPhase 4Post Graduate Institute of Medical Education and Research, ChandigarhNCT06625450Written as Tofacitinib plus mesalamine
- Phase III Multicentre Trial of Oral Mesalazine in Patients With Mild to Moderate Ulcerative Colitis.Not yet recruitingPhase 3Faes Farma, S.A.NCT06176560Written as Mesalazine
- Adherence of a 1.600 mg Single Tablet 5-ASA Treatment of Ulcerative ColitisRecruitingPhase 4Flemming BendtsenNCT04133194Written as Mesalazine
- Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative ColitisCompletedPhase 4Sixth Affiliated Hospital, Sun Yat-sen UniversityNCT05205603Written as Mesalazine
- A Study to Assess Adverse Events and Change in Disease Condition of Mesalamine Capsules in Children Aged 5 to 17 Years With Ulcerative ColitisWithdrawnPhase 3AbbVieNCT05316220Written as Mesalamine
- ChAracterizing the Remission Status in Patients With Ulcerative Colitis Treated by 5-ASACompletedPhase 4Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZWNCT05992142Written as 5-ASA
- Mesalazine Oral Suspension in Active Eosinophilic EsophagitisCompletedPhase 2Dr. Falk Pharma GmbHNCT05488405Written as Mesalamine Oral Product
- Aminosalicylic Acid Withdrawal Study in Long Standing Inactive Ulcerative ColitisCompletedNot applicableChinese University of Hong KongNCT02537210Written as Mesalazine
- Role of Intestinal Protozoa and Helminths in the Course of Ulcerative ColitisActive, not recruitingPhase 1/2Research Institute of Epidemiology, Microbiology and Infectious Diseases, UzbekistanNCT03441893Written as Mesalazine 250Mg Tablet and nitazoxanide 500Mg Oral Tablet
- The Efficacy of Topical Mesalazine Sustained-Release Tablets in Crohn's Disease Patients With Oral UlcerWithdrawnPhase 3Xijing Hospital of Digestive DiseasesNCT02769494Written as Mesalazine Sustained-Release Tablets
- Corticosteroids+5-aminosalicylic Acid Compared to Corticosteroids in the Treatment of Moderate-severe Ulcerative ColitisCompletedPhase 4Sheba Medical CenterNCT01941589Written as oral 5-ASA+/-topical 5-ASA+IV corticosteroids / PO Methylprednisolone
- Mesalamine 2 g Sachet for the Maintenance of Clinical and Endoscopic Remission in Ulcerative Colitis (UC)CompletedPhase 3Ferring PharmaceuticalsNCT02522780Written as Mesalamine
- Bioavailability Study of Two Mesalamine 4 gm/60 ml Rectal Enema FormulationsCompletedNot applicablePadagis LLCNCT00802451Written as Mesalamine
- Sulfamethoxazole Drug Interaction Study With MMX® Mesalazine/MesalamineCompletedPhase 1ShireNCT01469637Written as Sulfamethoxazole + MMX Mesalazine/mesalamine
- Safety and Tolerability of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis.CompletedPhase 3ShireNCT00151944Written as SPD476 (mesalazine)
- Efficacy and Safety of SPD476 in Maintaining Remission in Patients With Ulcerative ColitisCompletedPhase 3ShireNCT00151892Written as SPD476
See all 93 studies that test Mesalamine →
Given in every arm · 20 — Mesalamine is usual care beside what is tested
- Efficacy of Acupuncture-Mesalazine Combination Therapy in Ulcerative Colitis.RecruitingNot applicableQin YuNCT07389824Written as Mesalazine
- Pentoxifylline in Patients With Ulcerative ColitisRecruitingPhase 2Ihab Elsayed HassanNCT07349472Written as Mesalamine
- Rupatadine in Patients With Ulcerative ColitisRecruitingPhase 2Alexandria UniversityNCT07064707Written as Mesalamine
- Nitazoxanide in Patients With Ulcerative ColitisRecruitingPhase 2Alexandria UniversityNCT06993974Written as Mesalamine
- Beneficial Effect of Silymarin in Ulcerative ColitisRecruitingPhase 2Tanta UniversityNCT06213857Written as Mesalamine
- Fecal Microbiota Transplantation for Ulcerative ColitisRecruitingPhase 2/3Guangzhou First People's HospitalNCT03804931Written as 5-Aminosalicylic acid(5-ASA) and/or Prednisone
- Clinical Study to Evaluate the Possible Efficacy of Nifuroxazide in Patient With Ulcerative ColitisCompletedPhase 2/3Mostafa BahaaNCT05988528Written as Mesalamine
- Repurposing Fenofibrate in Modulating AMPK/NLRP3 Inflammasome in Patients With Ulcerative ColitisCompletedPhase 2Tanta UniversityNCT05781698Written as Mesalamine
- Dapagliflozin in Patients With Ulcerative ColitisCompletedPhase 2/3Mostafa BahaaNCT05986136Written as Mesalamine
- Atorvastatin Efficacy and Safety in Patients With Ulcerative ColitisCompletedPhase 2Tanta UniversityNCT05567068Written as Mesalamine
- Minocyclin in Ulcerative Colitis as Added on TherapyCompletedPhase 2Mostafa BahaaNCT06201793Written as Mesalazine
- Administration of Hydroxychloroquine (Plaquenil) to African Americans and Hispanics for the Treatment of Mild to Severe Ulcerative ColitisActive, not recruitingPhase 1/2Icahn School of Medicine at Mount SinaiNCT05119140Written as Mesalamine
- Combination Corticosteroids+5-aminosalicylic Acids Compared to Corticosteroids Alone (for Ulcerative Colitis).CompletedPhase 3Centre Hospitalier Universitaire de Saint EtienneNCT02665845Written as 5-ASA
- PRObiotic VSL#3® for Maintenance of Clinical and Endoscopic REMission in Ulcerative ColitisTerminatedNot applicableVSL PharmaceuticalsNCT03415711Written as Mesalamine
- Mercaptopurine Therapy in Ulcerative ColitisStatus unknownPhase 3Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT02910245Written as Mesalamine
- Predicting Response to Standardized Pediatric Colitis TherapyCompletedPhase 4Connecticut Children's Medical CenterNCT01536535Written as Mesalazine
- Randomized Placebo-Controlled Trial of Budesonide Multi-Matrix System (MMX®) 9 Milligrams (mg) in Participants With Ulcerative Colitis Currently on a 5-Aminosalicylic Acid (5-ASA)CompletedPhase 3Bausch Health Americas, Inc.NCT01532648Written as 5-ASA
- Bio-enhanced Curcumin as an Add-on Treatment in Maintaining Remission of Ulcerative ColitisStatus unknownPhase 3Asian Institute of Gastroenterology, IndiaNCT02683759Written as 5-Aminosalicyclic acid
- Bio-enhanced Curcumin as an Add-On Treatment in Mild to Moderate Ulcerative ColitisStatus unknownPhase 3Asian Institute of Gastroenterology, IndiaNCT02683733Written as 5-Aminosalicylic acid
- Curcumin + Aminosalicylic Acid (5ASA) Versus 5ASA Alone in the Treatment of Mild to Moderate Ulcerative ColitisCompletedPhase 3Sheba Medical CenterNCT01320436Written as 5-aminosalicylic acid
As the comparator · 20 — what is tested is compared with Mesalamine
- Comaprison of Efficacy and Safety Between Etrasimod vs Mesalazine in Chinese Adults With Active UCNot yet recruitingPhase 4Sir Run Run Shaw HospitalNCT07782242Written as mesalazine
- Clinical Study to Evaluate the Possible Efficacy and Safety of Febuxostat in Patients With Ulcerative Colitis Treated With MesalamineNot yet recruitingEarly Phase 1Tanta UniversityNCT06525974Written as Mesalamine
- Fenofibrate in Ulcerative ColitisCompletedPhase 2/3Tanta UniversityNCT05753267Written as Mesalamine
- Effectiveness of Fecal Microbiota Transplantation as add-on Therapy in Mild-to-moderate Ulcerative ColitisCompletedNot applicableBogomolets National Medical UniversityNCT05538026Written as Mesalazine
- Faecal Bacteriotherapy for Ulcerative ColitisCompletedPhase 2Institute for Clinical and Experimental MedicineNCT03104036Written as Mesalazine 4G Enema
- To Evaluate the Efficacy and Safety of FE 999315 in Japanese Subjects With Mild to Moderate Active Ulcerative ColitisCompletedPhase 3Ferring PharmaceuticalsNCT03412682Written as Mesalazine (3,600 mg)
- Phosphatidylcholine (LT-02) vs. Placebo vs. Mesalamine for Maintenance of Remission in Ulcerative Colitis (PROTECT-2)CompletedPhase 3Dr. Falk Pharma GmbHNCT02280629Written as Mesalamine
- (CB-01-02/01) Randomized Placebo Controlled Trial of Budesonide-multi-matrix System (MMX™) 6 mg and 9 mg in Patients With Ulcerative ColitisCompletedPhase 3Bausch Health Americas, Inc.NCT00679432Written as Asacol® 400 mg
- Budesonide vs. Mesalazine vs. Budesonide/Mesalazine Suppository Combination Therapy in Acute Ulcerative ProctitisCompletedPhase 2Dr. Falk Pharma GmbHNCT01966783Written as Mesalazine 1 g suppository
- Fecal Microbiota Therapy Vs 5-aminosalicylates for Induction of Remission in Newly Diagnosed Mild-moderately Active UCStatus unknownPhase 3Dayanand Medical College and HospitalNCT03716388Written as Mesalamine Granules
- TP05 for the Treatment of Mild to Moderate Active Ulcerative Colitis (UC)CompletedPhase 3Tillotts Pharma AGNCT01903252Written as Asacol 400 mg
- Cimzia Versus Mesalamine for Crohn's RecurrenceTerminatedPhase 4Milton S. Hershey Medical CenterNCT01696942Written as Mesalamine
- Conventional Step-Up Versus Infliximab Monotherapy in Patients With Ulcerative Colitis (P05553)TerminatedPhase 3Merck Sharp & Dohme LLCNCT00984568Written as 5-aminosalicylic acid
- Casein Glycomacropeptide in Active Distal Ulcerative Colitis (Pilot Study)CompletedNot applicableUniversity of AarhusNCT01534312Written as Maximal oral 5ASA
- Phase III Study of D9421-C 9 mg in Patients With Active Crohn's Disease in JapanCompletedPhase 3AstraZenecaNCT01514240Written as Mesalazine tablets
- Standardized Fecal Microbiota Transplantation for Inflammatory Bowel DiseaseStatus unknownPhase 2Yanling WeiNCT02335281Written as Mesalazine
- Oral Budesonide vs. Oral Mesalazine in Active Crohn's Disease (CD)CompletedPhase 3Dr. Falk Pharma GmbHNCT00300118Written as mesalazine
- Preventing Postoperative Relapse in Crohn's Disease Patients at Risk: Azathioprine Versus MesalazineCompletedPhase 3Dr. Falk Pharma GmbHNCT00946946Written as Mesalazine
- Budesonide Capsules Versus Mesalazine Granules in Active Ulcerative Colitis (UC)CompletedPhase 3Dr. Falk Pharma GmbHNCT00747110Written as mesalazine
- A Phase II Study to Explore the Safety and Activity of Dersalazine in Patients With Mild to Moderate Ulcerative ColitisCompletedPhase 2Palau Pharma S.L.U.NCT00808977Written as Mesalazine
Codes
What other systems call Mesalamine · ClinicalTrials.gg INT008722
- MeSH (NLM) D019804MesalamineConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 4Q81I59GXCMESALAMINEConfirmed FDA, NLM
- RxNorm 52582One source FDA
- NCI Thesaurus C29249MesalamineOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D019804 | Mesalamine | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 4Q81I59GXC | MESALAMINE | Confirmed FDA, NLM |
| RxNorm | 52582 | — | One source FDA |
| NCI Thesaurus | C29249 | Mesalamine | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.