Marfan Syndrome clinical trials
The registry lists 61 studies for Marfan Syndrome across more than 10 countries. 15 are recruiting or about to start. 43 of them are mainly about Marfan Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
IRCCS Policlinico S. Donato (9) · University Hospital, Toulouse (4) · Barts & The London NHS Trust (3) · Assistance Publique - Hôpitaux de Paris (3) · Stanford University (3) · University of Aarhus (2) · Hospices Civils de Lyon (2) · Baylor College of Medicine (2)
What is being tested here
Drugs under test in Marfan Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Beta blockers 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8
- Nov 2026PregnAncy-Related Aortic DISsEction in China · DeltaHealth Hospital · Shanghai
- Dec 2026Transcriptomic Study of Adult Population With Marfan Syndrome · IRCCS Policlinico S. Donato
- Dec 2026Fibroblasts and Thoracic Aortic Aneurysms: in Vitro Characterization in With Marfan Syndrome and Genetic Aortic Diseases · IRCCS Policlinico S. Donato
- Feb 2027Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study · Hospices Civils de Lyon
- Feb 2027Psychological Support in Adult Patients With Marfan Syndrome · IRCCS Policlinico S. Donato
- Mar 2027ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria · IRCCS Policlinico S. Donato
- Mar 2027Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos Syndrome · IRCCS Policlinico S. Donato
- Jun 2027Marfan Syndrome (MFS) and Facial Dysmorphism: Non-invasive 3D Assessment · IRCCS Policlinico S. Donato
Who these studies take
Of the 12 Marfan Syndrome studies recruiting now, 7 (58%) set no upper age limit and 4 (33%) stop at 75 or younger. 9 (75%) take children under 18. 2 (17%) are for women only and 0 (0%) for men only; 1 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 8 (67%) | 8 (67%) |
| 18 | 11 (92%) | 9 (75%) |
| 30 | 10 (83%) | 8 (67%) |
| 40 | 10 (83%) | 8 (67%) |
| 50 | 9 (75%) | 8 (67%) |
| 65 | 8 (67%) | 8 (67%) |
| 75 | 8 (67%) | 8 (67%) |
| 85 | 8 (67%) | 8 (67%) |
Across all 61 studies, recruiting or not: 44% stop at 75 or younger and 43% at 65; 64% take children; 3% are for women only and 0% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 50 of 61. Browse all 61 → or search them.
- Marfan Syndrome (MFS) and Facial Dysmorphism: Non-invasive 3D AssessmentRecruitingNCT057024761 country
- Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos SyndromeRecruitingNCT071696691 country
- Psychological Support in Adult Patients With Marfan SyndromeRecruitingNCT057125771 country
- Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 StudyRecruitingNCT041946191 country
- ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared CriteriaRecruitingNCT067822301 country
- PregnAncy-Related Aortic DISsEction in ChinaRecruitingNCT076722101 country
- Fibroblasts and Thoracic Aortic Aneurysms: in Vitro Characterization in With Marfan Syndrome and Genetic Aortic DiseasesEnrolling by invitationNCT067867541 country
- National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter RegistryRecruitingNCT065461371 country
- Nutritional Ketosis MarfanNot yet recruitingNCT07495267Not applicable
- Biological Collection for Marfan and Related SyndromesRecruitingNCT049704591 country
- Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan SyndromeRecruitingNCT05838235Not applicable1 country
- Clinical and Psychosocial Factors Associated With Physical Activity Level in Adults With Marfan SyndromeNot yet recruitingNCT074193861 country
- Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made DevicesRecruitingNCT02050113Not applicable1 country
- Genome-wide Epistasis for Cardiovascular Severity in Marfan StudyRecruitingNCT062570041 country
- Marfan Syndrome Moderate Exercise Trial IIRecruitingNCT05809323Not applicable1 country
- Fatigue, Depressive Disorders and Insomnia in Adult Patients With Marfan Syndrome and Ehlers-Danlos Syndrome: SurveyCompletedNCT057125641 country
- APPLICATION OF THERAPEUTIC PHOTOGRAPHY AND EXPRESSIVE WRITING IN THE MANAGEMENT OF PATIENTS WITH MARFAN SYNDROMECompletedNCT06872268Not applicable1 country
- Analysis of Muscular Properties in Patients With MFS and EDSCompletedNCT057209231 country
- Transcriptomic Study of Adult Population With Marfan SyndromeActive, not recruitingNCT057001751 country
- Living With Marfans and Your Aorta: Surgical Outcomes StudyCompletedNCT047766811 country
- Pathogenetic Basis of Aortopathy and Aortic Valve DiseaseActive, not recruitingNCT034406971 country
- Cardiorespiratory and Muscular Rehabilitation of Children and Young Adults With Marfan Syndrome.CompletedNCT03236571Not applicable1 country
- Genotypes and Craniofacial Phenotypes in Orthodontic Patients With Marfan and Loeys-Dietz SyndromesCompletedNCT073607041 country
- Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan DiseaseCompletedNCT051233391 country
- Measurement of Heart-carotid Pulse Wave Velocity (hcPWV) by Laser Doppler Vibrometry (LDV)CompletedNCT05711693Not applicable1 country
- Towards Optimal Treatment of Marfan SyndromeCompletedNCT059446141 country
- Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan SyndromeCompletedNCT00429364Phase 33 countries
- Single-Session "Empowered Relief" Class for Marfan Syndrome and Related ConditionsCompletedNCT05980104Not applicable1 country
- Artisan Aphakia Lens for the Correction of Aphakia in ChildrenSuspendedNCT01547442Not applicable2 countries
- Mortality and Morbidity Outcomes in MarfansCompletedNCT047741721 country
- Proximal Aortopathy in Scotland - Epidemiology and Surgical OutcomesActive, not recruitingNCT053898651 country
- Living With Marfan Syndrome and Your AortaCompletedNCT047766681 country
- Marfan Syndrome Moderate Exercise PilotCompletedNCT04641325Not applicable1 country
- Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockersCompletedNCT00782327Phase 31 country
- Surgical Treatment of Marfan Syndrome With Subluxation LensStatus unknownNCT055784691 country
- Effects of Personalized Training at Home Combining Endurance and Resistance in Patients Suffering From Marfan SyndromeCompletedNCT04553094Not applicable1 country
- Safety and Performance of POLYTHESE® Vascular ProsthesisCompletedNCT055160431 country
- Tele-Clinic Visits in Pediatric Marfan Patients Using Parental Echo: The Future?CompletedNCT03581682Not applicable1 country
- Effect on the Quality of Life of a Therapeutic Education Program in Patients With Marfan SyndromeStatus unknownNCT047314931 country
- Children and Adolescents With Marfan Syndrome: 10,000 Healthy Steps and BeyondCompletedNCT03567460Not applicable1 country
- Classifying Ectopia Lentis in Marfan Syndrome Into Five Grades of Increasing SeverityCompletedNCT043191071 country
- Thoracic Aortic Dilatation SyndromesCompletedNCT021116681 country
- Studies of Heritable Disorders of Connective TissueCompletedNCT002706861 country
- Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFSCompletedNCT01715207Phase 31 country
- Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy SyndromesCompletedNCT022134841 country
- Development of a Blood Test for Marfan SyndromeStatus unknownNCT021489001 country
- National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular ConditionsCompletedNCT013221651 country
- Generation of Marfan Syndrome and Fontan Cardiovascular Models Using Patient-specific Induced Pluripotent Stem CellsStatus unknownNCT028150721 country
- Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan SyndromeCompletedNCT017606681 country
- Circulating Transforming Growth Factor Beta (TGF-β) in Individuals With Marfan SyndromeWithdrawnNCT01361087Phase 31 country