Drug
Lactulose clinical trials
- studies test it
- 55
- open now
- 5
- in phase 3
- 8
- first study started
- 1994
Keep track of what changes. Save the Lactulose studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
55 studies that test it; most in 2013 (6)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 2000 | 2 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 2 |
| 2007 | 1 |
| 2008 | 5 |
| 2009 | 3 |
| 2010 | 3 |
| 2011 | 2 |
| 2013 | 6 |
| 2014 | 4 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2020 | 1 |
| 2021 | 3 |
| 2022 | 3 |
| 2023 | 3 |
| 2024 | 4 |
| 2025 | 2 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 2
- Phase 2
- 8
- Phase 3
- 8
- Phase 4
- 18
- No phase
- 21
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 9 · Other 46
Institute of Liver and Biliary Sciences, India (4) · University of Michigan (2) · Avva Rus, JSC (2) · Solvay Pharmaceuticals (2) · Bnai Zion Medical Center (2) · Norgine (2) · Tongji Hospital (2) · Govind Ballabh Pant Hospital (2)
Often tested with
Tested in the same studies.
Rifaximin (11) · Polyethylene Glycols (6) · Polyethylene glycol 3350 (2) · Ornithylaspartate (2) · Probiotic (1) · Natamycin (1) · Suppositories (1) · Prucalopride (1)
Studies
Open first, then newest update. How each study uses Lactulose is read from its arms, and is right about nine times in ten.
Testing it · 55
- Oral Lactulose for Gastrointestinal Recovery After Complex AppendectomyRecruitingNot applicableNanchong Central HospitalNCT07589465Written as Lactulose oral solution
- Lactulose to Improve Gut Health in Cancer Patients Receiving ImmunotherapyRecruitingPhase 1/2University of ChicagoNCT07354100Written as Lactulose
- Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.Not yet recruitingNot applicableNicosia General HospitalNCT06995586Written as Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose
- Goal Directed Ammonia Lowering Therapy in Hyperammonemic ACLF Patients With no Overt HE to Reduce Major Adverse Liver Related Outcomes (GOAL Trial)Not yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT06808009Written as Lactulose
- Clinical Study on the Application of Lactulose Combined with Linaclotide in Bowel Preparation for ColonoscopyEnrolling by invitationPhase 4Haifeng LanNCT06748638Written as Lactulose
- Combination of Lactulose and Polyethylene Glycol Electrolytes Powder (PEG-ELS) for Bowel Preparation in Type II Diabetes Mellitus PatientsCompletedNot applicableGeneral Hospital of Shenyang Military RegionNCT07084350Written as lactulose
- Ultra-low Split-dose Oral Lactulose vs High-volume Split-dose Polyethylene Glycol as Bowel Preparation for Outpatient Colonoscopies.CompletedNot applicableNational Institute of Medical Sciences and Nutrition, Salvador ZubiranNCT07787897Written as lactulose
- LiveSMART Trial to Prevent Falls in Patients With CirrhosisCompletedPhase 3University of MichiganNCT05794555Written as Lactulose
- Bowel Preparation in Colonoscopy: Lactulose vs Polyethyleneglycol, Randomized Double-blind Comparative Clinical Trial, Multicenter Study.CompletedPhase 4Hospital Civil de GuadalajaraNCT06666556Written as Bowel preparation before colonoscopy
- A Trial for Comparing Rifaximin, Probiotic and L-ornithine- L Aspartate With Lactulose in Overt Hepatic Encephalopathy.CompletedPhase 4Qurratul Ain JamilNCT07037394Written as Probiotic plus lactulose
- Efficacy and Safety of Natamycin and Lactulose Vaginal Suppositories in Treatment of Vulvovaginal CandidiasisCompletedPhase 3Avva Rus, JSCNCT06411314Written as Natamycin + Lactulose 100 mg + 300 mg vaginal suppositories
- Lactulose vs. Polyethylene Glycol as Bowel Preparation for Colonoscopy in AdultsCompletedNot applicableHospital de Clínicas Dr. Manuel QuintelaNCT05726344Written as Lactulose
- A Trial to Improve Quality of Life in People With CirrhosisCompletedPhase 2/3University of MichiganNCT05061992Written as Lactulose
- Effectiveness of Oral Lactulose Versus Lactulose Enema in Hepatic EncephalopathyStatus unknownPhase 4Khyber Medical College, PeshawarNCT05788627Written as Lactulose
- Effect of Lactulose and/or Polyethylene Glycol Solution for Bowel Preparation for Colonscopy ProceduresCompletedPhase 3Sichuan UniversityNCT05076799Written as 200 ml lactulose
- Improved Bowel Preparation Method for Colonoscopy Based on Different Risk StratificationCompletedNot applicableRenmin Hospital of Wuhan UniversityNCT04582942Written as PEG+lactulose
- Comparison of Oral Lactulose Versus Polyethylene Glycol for Bowel Preparation in Low-risk PatientsCompletedNot applicableZhang Xiaofeng,MDNCT05648318Written as Lactulose oral solution
- Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhotic PatientsStatus unknownEarly Phase 1Madonna Magdy FahmyNCT05279586Written as lactulose
- Rifaximin Versus Lactulose in Renal FailureWithdrawnPhase 4Weill Medical College of Cornell UniversityNCT00748904Written as Lactulose
- Comparison of Oral Lactulose Versus Polyethylene Glycol for Bowel PreparationStatus unknownNot applicableFirst People's Hospital of HangzhouNCT04794049Written as Lactulose
See all 55 studies that test Lactulose →
Given in every arm · 14 — Lactulose is usual care beside what is tested
- Effect of Single vs Repeated Cycles of a Combination of Granulocyte Colony Stimulating Factor and Darbepoetin vs Standard Medical Treatment on Immunometabolic Profile in Patient With Early Decompensated Cirrhosis.RecruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT07002827Written as Lactulose
- UDCA to Prevent Post-TIPS Hepatic EncephalopathyNot yet recruitingNot applicableWest China HospitalNCT07273734Written as Lactulose
- Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE)RecruitingNot applicableGeneral Hospital of Shenyang Military RegionNCT06483737Written as Lactulose
- Effects of Lactulose on Gut Microbiota and Metabolism in Diabetic Constipated PatientsRecruitingNot applicablePeking Union Medical College HospitalNCT07065942Written as Lactulose oral solution
- BCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HERecruitingPhase 4Post Graduate Institute of Medical Education and Research, ChandigarhNCT06538077Written as Lactulose
- Efficacy of L-Ornithine L-Aspartate and Polyethylene Glycol in Cirrhotic Patients With Overt Hepatic EncephalopathyNot yet recruitingPhase 4Jinnah Postgraduate Medical CentreNCT05920213Written as Lactulose oral solution
- Efficacy and Safety of Nifuroxazide in the Treatment of Hepatic Encephalopathy in Egyptian Patients With Liver CirrhosisCompletedPhase 3Cairo UniversityNCT05754996Written as Lactulose
- Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF)CompletedPhase 1Post Graduate Institute of Medical Education and Research, ChandigarhNCT05700695Written as Lactulose
- Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLFCompletedPhase 1Post Graduate Institute of Medical Education and Research, ChandigarhNCT04238416Written as Lactulose
- Mode of Action of Ondansetron, a 5-HT Receptor 3 Antagonist, in Lactulose Induced DiarrhoeaCompletedPhase 4University of NottinghamNCT03833999Written as Lactulose
- PEG3350 in ACLF With Hepatic EncephalopathyStatus unknownPhase 4Post Graduate Institute of Medical Education and Research, ChandigarhNCT03987893Written as Lactulose
- Performance of 13C Mannitol for in Vivo Measurement of Small Intestinal PermeabilityCompletedPhase 1Mayo ClinicNCT02603822Written as Lactulose
- Nitazoxanide Plus Lactulose Versus Lactulose Alone Treatment of Hepatic EncephalopathyStatus unknownPhase 2/3Sherief Abd-ElsalamNCT02464124Written as Lactulose
- The Effects of Nitazoxanide in Hepatic EncephalopathyStatus unknownPhase 2Ain Shams UniversityNCT02334163Written as Oral lactulose
As the comparator · 16 — what is tested is compared with Lactulose
- A Prospective, Multicenter, Randomized, Parallel-controlled, Superiority TrialNot yet recruitingPhase 3First Teaching Hospital of Tianjin University of Traditional Chinese MedicineNCT07534995Written as Lactulose
- Effect of Probiotic on Gut Microbiota in Young Children With Functional ConstipationCompletedPhase 2Min-Tze LIONGNCT07360535Written as Lactulose Oral Liquid Product
- Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Cirrhosis;(PEGHE Trial)Status unknownPhase 4Aga Khan UniversityNCT04436601Written as Lactulose
- Lubiprostone for Functional Constipation in the Under 18 Years PatientsCompletedPhase 3Alexandria UniversityNCT05144295Written as Lactulose Oral Liquid Product
- Improved Bowel Cleansing Method for Colonoscopy Based on High Risk Population of Bowel PreparationStatus unknownNot applicableRenmin Hospital of Wuhan UniversityNCT05498714Written as PEG+lactulose
- Oral Administration of MB-102 Versus Dual Sugar Testing for Gut PermeabilityCompletedEarly Phase 1MediBeaconNCT03962998Written as Lactulose/Rhamnose solution
- Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal DisordersStatus unknownPhase 4RenJi HospitalNCT05134584Written as Lactulose
- Efficacy and Safety of E.Coli Nissle 1917 in Patients With Mild (Stage 1-2) or Minimal Hepatic EncephalopathyCompletedNot applicableBogomolets National Medical UniversityNCT04787276Written as Lactulose
- Efficacy and Safety of PEG 3350 for Treatment of Chronic ConstipationStatus unknownPhase 3Fakultas Kedokteran Universitas IndonesiaNCT03957668Written as Lactulose
- High Volume Plasmapheresis for Refractory Hepatic Encephalopathy in Liver Intensive Care Unit.WithdrawnNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT03115697Written as Lactulose
- To Assess Efficacy of Nutritional Therapy in Secondary Prophylaxis of Hepatic Encephalopathy Versus Lactulose in Patients With Liver Cirrhosis.WithdrawnNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT03161106Written as Lactulose
- To Compare Efficacy and Safety of Lactulose Versus Polyethylene Glycol for Treatment of Overt Hepatic Encephalopathy in Cirrhotics.Status unknownNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT03448770Written as Lactulose : 20-30gm
- A Clinical Standardization Study of the Preferred Acupuncture Treatment Protocol to Treat Functional ConstipationCompletedPhase 2Guang'anmen Hospital of China Academy of Chinese Medical SciencesNCT00508482Written as Lactulose
- Safety and Efficacy of AST-120 Compared to Lactulose in Patients With Hepatic EncephalopathyCompletedPhase 2Ocera TherapeuticsNCT00558038Written as lactulose
- Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of LifeCompletedPhase 2/3CD Pharma India Pvt. Ltd.NCT01008293Written as Lactulose
- Comparison of TCM and Laxatives for Adults With Chronic ConstipationCompletedPhase 3National Taiwan University HospitalNCT00745147Written as Duphalac
Codes
What other systems call Lactulose · ClinicalTrials.gg INT007722
- MeSH (NLM) D007792LactuloseOne source ClinicalTrials.gov
- UNII (FDA) 9U7D5QH5AELACTULOSEOne source FDA
- RxNorm 6218One source FDA
- NCI Thesaurus C29148LactuloseOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D007792 | Lactulose | One source ClinicalTrials.gov |
| UNII (FDA) | 9U7D5QH5AE | LACTULOSE | One source FDA |
| RxNorm | 6218 | — | One source FDA |
| NCI Thesaurus | C29148 | Lactulose | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.