Hepatic Encephalopathy clinical trials
The registry lists 225 studies for Hepatic Encephalopathy across more than 10 countries. 53 are recruiting or about to start. 164 of them are mainly about Hepatic Encephalopathy (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-28.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Now Active, not recruiting
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Who runs them
Hunter Holmes Mcguire Veteran Affairs Medical Center (8) · Bausch Health Americas, Inc. (7) · Post Graduate Institute of Medical Education and Research, Chandigarh (7) · NYU Langone Health (5) · University of Michigan (5) · University of Aarhus (5) · Air Force Military Medical University, China (5) · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (5)
What is being tested here
Drugs under test in Hepatic Encephalopathy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Equivalence of Electronic vs Paper-based PHES in Diagnosing Hepatic Encephalopathy · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
- Dec 2026Appropriate Management of Hepatic EncePhalopaThy AmonG cirrhOtic patieNts Admitted to Internal Medicine · Fadoi Foundation, Italy
- Dec 2026Diagnosing Minimal Hepatic Encephalopathy · Esbjerg Hospital - University Hospital of Southern Denmark
- Dec 2026Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy · Massachusetts General Hospital
- Dec 2026Affect of Melatonin on Sleep and Cognition in Cirrhosis · Weill Medical College of Cornell University
- Dec 2026VICIS - Vienna Cirrhosis Study · Medical University of Vienna
- Jan 2027Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy · Mayo Clinic
- Jan 2027Fecal Microbiota Transplantation for the Treatment of Refractory Hepatic Encephalopathy After TIPS Surgery · Air Force Military Medical University, China
- Apr 2027Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis · Asian Institute Of Medical Sciences
- Jun 2027UDCA to Prevent Post-TIPS Hepatic Encephalopathy · West China Hospital
Who these studies take
Of the 29 Hepatic Encephalopathy studies recruiting now, 11 (38%) set no upper age limit and 13 (45%) stop at 75 or younger. 1 (3%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (3%) | 1 (3%) |
| 18 | 27 (93%) | 27 (93%) |
| 30 | 29 (100%) | 29 (100%) |
| 40 | 29 (100%) | 29 (100%) |
| 50 | 29 (100%) | 29 (100%) |
| 65 | 28 (97%) | 28 (97%) |
| 75 | 22 (76%) | 22 (76%) |
| 85 | 13 (45%) | 13 (45%) |
Across all 225 studies, recruiting or not: 51% stop at 75 or younger and 15% at 65; 7% take children; 0% are for women only and <1% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hepatic Encephalopathy studies take
Of 25 interventional studies with no phase under Hepatic Encephalopathy, half reached primary completion within 32 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 32 mo15–72 · 25 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- 4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in CirrhosisOct 13, 2026NCT07554183
Results posted1
Newly registered2
- Effect of Mini-Program Monitoring on Hepatic Encephalopathy in Post-TIPS PatientsOct 28, 2026NCT07901556
- Equivalence of Electronic vs Paper-based PHES in Diagnosing Hepatic EncephalopathyOct 14, 2026NCT07874204
Studies
Recruiting first, then most recently updated. Showing 50 of 225. Browse all 225 → or search them.
- Effect of Mini-Program Monitoring on Hepatic Encephalopathy in Post-TIPS PatientsNot yet recruitingNCT07901556Not applicable
- Daridorexant for Sleep Disturbance in Adults With Liver CirrhosisNot yet recruitingNCT07830303Phase 41 country
- Equivalence of Electronic vs Paper-based PHES in Diagnosing Hepatic EncephalopathyNot yet recruitingNCT07874204Not applicable
- 4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in CirrhosisRecruitingNCT07554183Not applicable1 country
- A Prospective Cohort Study on the Epidemiological Investigation, Diagnosis, and Treatment of Hepatic EncephalopathyNot yet recruitingNCT076126701 country
- Electronic PHES vs Paper-based PHES for Hepatic EncephalopathyNot yet recruitingNCT07852416Not applicable1 country
- Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic EncephalopathyRecruitingNCT04096014Not applicable1 country
- RENEW: Study of Porcine Liver Support in Participants With Acute-on-Chronic Liver FailureNot yet recruitingNCT07429838Phase 1/21 country
- Coil-Assisted Small-Diameter Covered-Stent Shunt Reduction for Refractory Hepatic Encephalopathy After TIPSRecruitingNCT07799948Not applicable1 country
- Affect of Melatonin on Sleep and Cognition in CirrhosisRecruitingNCT07046429Not applicable1 country
- Fecal Microbiota Transplantation for the Treatment of Refractory Hepatic Encephalopathy After TIPS SurgeryRecruitingNCT07683936Early Phase 11 country
- Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram TrialNot yet recruitingNCT07168395Not applicable
- Comparison of Underdilated Versus Standard TIPS in Preventing Variceal Rebleeding in Patients With CirrhosisRecruitingNCT07253389Not applicable1 country
- Underdilated VCX-TIPS Versus EVL Plus NSBB for Secondary Prophylaxis of Variceal Bleeding in CirrhosisNot yet recruitingNCT07587671Not applicable1 country
- Endoscopic Shunts Embolization for Refractory Hepatic EncephalopathyNot yet recruitingNCT07553858Not applicable1 country
- Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)Not yet recruitingNCT07528690Phase 21 country
- Apixaban-PK Trial: Preventing Portal Hypertension Complications in CirrhosisRecruitingNCT07521332Phase 41 country
- Evaluation of the Outcome of Fecal Microbiota TransplantationNot yet recruitingNCT07454408Phase 1/21 country
- A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With CirrhosisRecruitingNCT06461208Phase 31 country
- The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)RecruitingNCT074180081 country
- Development of a Cognitive Tool for Rapid and Reliable Screening of Minimal Hepatic Encephalopathy: Pilot StudyRecruitingNCT066191061 country
- Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic EncephalopathyRecruitingNCT06425380Not applicable1 country
- Underdilated-stent Technique Improves Post-TIPS EncephalopathyRecruitingNCT07349654Not applicable1 country
- UDCA to Prevent Post-TIPS Hepatic EncephalopathyNot yet recruitingNCT07273734Not applicable1 country
- Psychometric Hepatic Encephalopathy Score in Prediction of Minimal Hepatic Encephalopathy in Compensated Cirrhotic PatientsNot yet recruitingNCT07272707
- VICIS - Vienna Cirrhosis StudyRecruitingNCT032676151 country
- Study on Proteomic and Microbiome Changes in Patients With Hepatic Encephalopathy (HE)Not yet recruitingNCT071501951 country
- Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE)RecruitingNCT06483737Not applicable1 country
- Mechanisms of Perioperative Systemic Inflammation in the Development of PND in Cirrhotic PatientsNot yet recruitingNCT07082946
- International Registry of Congenital Portosystemic Shunt (IRCPSS)Enrolling by invitationNCT0604190616 countries
- BCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HERecruitingNCT06538077Phase 41 country
- Correlation Between Serum Albumin Level and Severity of Hepatic Encephalopathy in Patients With Chronic Liver Disease in Sohag University HospitalRecruitingNCT069539211 country
- 7.0T Magnetic Resonance Imaging Study for Hepatic EncephalopathyNot yet recruitingNCT069232541 country
- A Study to Evaluate Role of Inhaled Amikacin to Prevent Ventilator Associated Pneumonia in Patients With CirrhosisRecruitingNCT06808074Phase 41 country
- Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and LactuloseRecruitingNCT04073290Phase 42 countries
- Faecal Microbiota Transplantation for Liver CirrhosisRecruitingNCT04932577Phase 2/31 country
- Diagnosing Minimal Hepatic EncephalopathyEnrolling by invitationNCT054339481 country
- Small Diameter TIPS in Patients with Severe Liver Atrophy and Variceal BleedingNot yet recruitingNCT06589531Not applicable
- Safety and Efficacy of Fecal Microbiota TransplantationRecruitingNCT04014413Not applicable1 country
- Hepatic Encephalopathy Prevention With Polydextrose After TIPS: Pilot Study (POEME)RecruitingNCT05206487Not applicable1 country
- Prospective Cohort Study of Complications and Outcomes in CirrhosisRecruitingNCT063745111 country
- Utility of the Clamping Bean Test (CBT) for Covert Hepatic Encephalopathy ScreeningEnrolling by invitationNCT063671271 country
- Vegetarian Versus Non Vegetarian Based Diet in the Recurrence of Hepatic Encephalopathy in Patients With Cirrhosis: An Open Label Pilot StudyRecruitingNCT063280881 country
- Revealing Engagement Patterns Among Hepatic Encephalopathy PatientsNot yet recruitingNCT062019881 country
- Throid Dysfunction in Liver Failure and Its Eddects Upon OutcomeRecruitingNCT061793681 country
- Vegetable Proteins Versus Mixed Animal Proteins on the Outcome of Hepatic EncephalopathyNot yet recruitingNCT06075875Not applicable1 country
- Efficacy of Lactoferrin as an Adjunct Therapy in Patients With Hepatic EncephalopathyNot yet recruitingNCT06072521Phase 21 country
- Role of Sarcopenia and Nutritional/Physical Therapy Intervention in Post-TIPS Hepatic EncephalopathyRecruitingNCT05346029Not applicable1 country
- Microbiota, Sarcopenia, and Hepatic Encephalopathy Change in Cirrhotic Patients Before and After RehabilitationRecruitingNCT06040814Not applicable1 country
- Efficacy of L-Ornithine L-Aspartate and Polyethylene Glycol in Cirrhotic Patients With Overt Hepatic EncephalopathyNot yet recruitingNCT05920213Phase 41 country