Fibrosis clinical trials

The registry lists 1,270 studies for Fibrosis across more than 10 countries. 276 are recruiting or about to start. 302 of them are mainly about Fibrosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed: 626
Recruiting: 196
Status unknown: 187
Terminated: 85
Not yet recruiting: 62
Active, not recruiting: 52

Phase

Phase 2: 214
Phase 3: 152
Phase 4: 117
Phase 1: 93
Early Phase 1: 7

Where

United States: 415
France: 172
China: 128
Spain: 85
United Kingdom: 85
Italy: 80

Who runs them

Assistance Publique - Hôpitaux de Paris (37) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (26) · Institute of Liver and Biliary Sciences, India (24) · Northern Jiangsu People's Hospital (19) · Hospices Civils de Lyon (18) · Gilead Sciences (18) · AbbVie (15) · Post Graduate Institute of Medical Education and Research, Chandigarh (13)

What is being tested here

Drugs under test in Fibrosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Apixaban	4	0	6
Carvedilol	3	2	9
Pentoxifylline	2	1	8
Resmetirom	2	2	4
Empagliflozin	2	0	4
Mosliciguat	2	1	3
Atorvastatin	2	1	3
Pravastatin	2	0	3
Efimosfermin alfa	2	2	2
Pegozafermin	2	2	2

Drug classes tested here Statins 5 open · Beta blockers 4 open · Factor Xa inhibitors 4 open · Tyrosine kinase inhibitors (TKIs) 3 open · Diuretics 2 open

Coming up

20phase 3 studies under way

88studies finish main data collection within a year4 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Dec 2026Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis · Phase 3 · VA Office of Research and Development
Mar 2027A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE) · Phase 3 · Madrigal Pharmaceuticals, Inc.
Mar 2027Efficacy of Esmolol in the Identification of Cardiovascular Disorders by Cirrhosis, Diabetes Mellitus and Cardiotoxic Treatments · Phase 3 · Consorcio Centro de Investigación Biomédica en Red (CIBER)
Aug 2027Evaluation of a Modified Bowel Preparation Regimen in Cirrhotic Patients Undergoing Colonoscopy · Phase 3 · Hospital do Divino Espírito Santo de Ponta Delgada
Nov 2026UNMASK: Unveiling the Pathobiology of Metabolic Dysfunction-Associated Steatotic Liver Disease for the Discovery of Novel Therapeutics and Biomarkers · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Nov 2026The Influence of Nutritional Factors on the Prognosis of Liver Cirrhosis Patients and the Exploration of Predictive Models · Juan Kang
Nov 2026EUS Guided Portal-systemic Pressure Gradient Measurement · Chinese University of Hong Kong
Dec 2026Human Umbilical Cord-mesenchymal Stem Cells Via Different Transplantation Routes in ESLD · General Hospital of Shenyang Military Region
Dec 2026EUS-guided Portal Pressure Gradient (PPG) Measurement: a Potential Alternative to the Traditional HVPG · Fundacio Privada Mon Clinic Barcelona
Dec 2026A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD · Pulmovant, Inc.

Who these studies take

Of the 196 Fibrosis studies recruiting now, 111 (57%) set no upper age limit and 53 (27%) stop at 75 or younger. 15 (8%) take children under 18. 2 (1%) are for women only and 2 (1%) for men only; 19 (10%) take healthy volunteers.

Recruiting studies that take each age, of 196
Age	Women	Men
10	11 (6%)	10 (5%)
18	181 (92%)	180 (92%)
30	186 (95%)	185 (94%)
40	190 (97%)	189 (96%)
50	192 (98%)	192 (98%)
65	189 (96%)	189 (96%)
75	169 (86%)	169 (86%)
85	128 (65%)	128 (65%)

Across all 1,270 studies, recruiting or not: 34% stop at 75 or younger and 10% at 65; 8% take children; 1% are for women only and 1% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Fibrosis studies take

Of 71 phase 2 interventional studies under Fibrosis, half reached primary completion within 36 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Phase 1	28 mo15–58 · 41 studies	—	—
Phase 2	36 mo19–58 · 71 studies	24 mo17–36 · 42 studies	—
Phase 3	33 mo18–70 · 52 studies	—	—
Phase 4	37 mo21–68 · 41 studies	—	36 mo20–76 · 38 studies
Interventional, no phase	32 mo18–50 · 194 studies	—	32 mo18–52 · 186 studies
Observational	48 mo21–105 · 186 studies	—	52 mo21–105 · 177 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Studies

Recruiting first, then most recently updated. Showing 50 of 1,270. Browse all 1,270 → or search them.