Drug
Isotretinoin clinical trials
Also written Accutane, 13-cis-Retinoic Acid, Amnesteem and Ro 4-3780.
Keep track of what changes. Save the Isotretinoin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
108 studies that test it; most in 2011 (8)
| Year | Studies |
|---|---|
| 1990 | 1 |
| 1991 | 1 |
| 1992 | 1 |
| 1993 | 1 |
| 1996 | 1 |
| 1998 | 1 |
| 1999 | 1 |
| 2000 | 1 |
| 2001 | 6 |
| 2002 | 3 |
| 2003 | 1 |
| 2004 | 4 |
| 2005 | 4 |
| 2006 | 2 |
| 2007 | 6 |
| 2008 | 2 |
| 2009 | 4 |
| 2010 | 4 |
| 2011 | 8 |
| 2012 | 3 |
| 2013 | 3 |
| 2014 | 1 |
| 2015 | 4 |
| 2016 | 3 |
| 2017 | 3 |
| 2018 | 5 |
| 2019 | 2 |
| 2020 | 4 |
| 2021 | 7 |
| 2022 | 3 |
| 2023 | 3 |
| 2024 | 4 |
| 2025 | 7 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 13 · Other 98
National Cancer Institute (NCI) (8) · Children's Oncology Group (7) · M.D. Anderson Cancer Center (4) · Dr. Reddy's Laboratories Limited (4) · Memorial Sloan Kettering Cancer Center (3) · Eastern Cooperative Oncology Group (3) · Federal University of São Paulo (3) · Kafrelsheikh University (3)
Often tested with
Tested in the same studies.
Etoposide (7) · Carboplatin (7) · Cyclophosphamide (5) · Doxorubicin (5) · Filgrastim (5) · Dinutuximab (4) · Sargramostim (4) · Temozolomide (4)
Studies
Open first, then newest update. How each study uses Isotretinoin is read from its arms, and is right about nine times in ten.
Testing it · 111
- Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color PatientsRecruitingPhase 3Centre Hospitalier Universitaire de NiceNCT06447480Written as ISOtretinoin 5 MG
- Comparison of Itraconazole With Itraconazole and Isotretinoin in the Treatment Duration, Safety a n d Cure Rate in Adult Patients of Tinea Corporis/ Cruris-A Randomised Controlled TrailNot yet recruitingPhase 4Pak Emirates Military HospitalNCT07675239Written as ISOtretinoin 20 MG
- Low-Dose Versus Conventional-Dose Oral Isotretinoin for Acne VulgarisNot yet recruitingPhase 4Pakistan Institute of Medical SciencesNCT07639073Written as Isotretinoin
- Isotretinoin vs. Doxycycline for Acneiform Rash in Patients Receiving Drugs That Target the MAPK PathwayNot yet recruitingPhase 2University of California, San FranciscoNCT07629167Written as Isotretinoin
- Weekly Isotretinoin vs Tetracycline for Moderate AcneRecruitingEarly Phase 1Medical University of South CarolinaNCT06225570Written as Isotretinoin
- Isotretinoin Versus Excimer Light an Adjuvant in Treating OnychomycosisRecruitingPhase 1Zagazig UniversityNCT06485505Written as ISOtretinoin 10 MG
- Isotretinoin vs hCG for Male Infertility Due to Low or Absent SpermEnrolling by invitationPhase 2University of NebraskaNCT07481370Written as isotretinoin
- Metronomic Chemotherapy in Wilms Tumor (MetroWilms-1906)RecruitingPhase 1/2Centre Oscar LambretNCT05384821Written as Cis-Retinoic acid
- Effect of Systemic Retinoic Acid Use on Micro Ribonucleic Acid (mRNA) ExpressionNot yet recruitingNot applicableMedipol UniversityNCT07142070Written as oral isotretinoin
- Assessment of Serum Catestatin Level in Acne Vulgaris PatientsRecruitingNot applicableAswan UniversityNCT07054398Written as Isotretinoin
- 13-cis Retinoic Acid (Isotretinoin) and Sperm ProductionNot yet recruitingPhase 4University Hospital, Strasbourg, FranceNCT06698263Written as Isotretinoin
- Oral Isotretinoin in Melasma a Randomized Controlled TrialRecruitingPhase 1Zagazig UniversityNCT06201624Written as Isotretinoin
- Therapy for Children With Advanced Stage NeuroblastomaCompletedPhase 2St. Jude Children's Research HospitalNCT01857934Written as Isotretinoin
- Effect of Oral Isotretinoin on Ocular Surface and Meibomian GlandsCompletedNot applicableBenha UniversityNCT07753811Written as isotretinoin
- Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent NeuroblastomaActive, not recruitingPhase 1National Cancer Institute (NCI)NCT01711554Written as Isotretinoin
- Effects of Isotretinoin on SmellCompletedNot applicableUşak UniversityNCT07309341Written as isotretinoin
- Systemic Isotretinoin Therapy and EyeCompletedNot applicableDemet MutluNCT07675460Written as Isotretinoin (13-cis-retinoic acid)
- Monoclonal Antibody Ch14.18, Sargramostim, Aldesleukin, and Isotretinoin After Autologous Stem Cell Transplant in Treating Patients With NeuroblastomaCompletedPhase 3National Cancer Institute (NCI)NCT01041638Written as Isotretinoin
- Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNETCompletedPhase 3Children's Oncology GroupNCT00392327Written as Isotretinoin
- Cabozantinib in Combination With 13-cis-Retinoic Acid in Children With Relapsed or Refractory Solid TumorsCompletedPhase 1Peter ZageNCT03611595Written as 13-cis-retinoic acid
See all 111 studies that test Isotretinoin →
Given in every arm · 18 — Isotretinoin is usual care beside what is tested
- Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk NeuroblastomaRecruitingPhase 3National Cancer Institute (NCI)NCT06172296Written as Isotretinoin
- Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)RecruitingPhase 3Children's Oncology GroupNCT03126916Written as Isotretinoin
- Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post ConsolidationRecruitingEarly Phase 1C17 CouncilNCT06942039Written as ISOtretinoin
- Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk NeuroblastomaCompletedPhase 2National Cancer Institute (NCI)NCT03786783Written as Isotretinoin
- Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With NeuroblastomaCompletedPhase 3National Cancer Institute (NCI)NCT00026312Written as Isotretinoin
- Evaluation of the Safety and Pharmacokinetics of Dinutuximab Beta As Maintenance Therapy in Chinese Participants With High-Risk NeuroblastomaCompletedPhase 1BeiGeneNCT05373901Written as 13-cis-Retinoic Acid
- Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk NeuroblastomaCompletedPhase 3Children's Oncology GroupNCT00567567Written as Isotretinoin
- Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.Status unknownPhase 3Mahmoud Ramadan mohamed ElkazzazNCT05016349Written as 13-Cis Retinoic Acid plus Tocopherol
- RA-2 13-cis Retinoic Acid (Isotretinoin)CompletedPhase 2University of WashingtonNCT02061384Written as 13-cis retinoic acid
- Long Term Continuous Infusion ch14.18/CHO Plus s.c. Aldesleukin (IL-2)Status unknownPhase 1/2St. Anna KinderkrebsforschungNCT01701479Written as Isotretinoin
- Anti-GD2 3F8 Monoclonal Antibody and GM-CSF for High-Risk NeuroblastomaCompletedNot applicableMemorial Sloan Kettering Cancer CenterNCT02100930Written as oral isotretinoin
- Cytosine Arabinoside and Mitoxantrone for Patients With Juvenile Myelomonocytic Leukemia Receiving Repeat Stem Cell TransplantationTerminatedPhase 1/2Masonic Cancer Center, University of MinnesotaNCT00609739Written as Cis-Retinoic acid
- Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive NeuroblastomaCompletedPhase 1Children's Oncology GroupNCT00070200Written as isotretinoin
- Bioequivalence Study of V0057 Versus a Reference Formulation After Single Administration in Healthy Male SubjectsCompletedPhase 1Pierre Fabre DermatologyNCT01861626Written as Isotretinoin
- Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With NeuroblastomaCompletedPhase 3Children's Oncology GroupNCT00004188Written as isotretinoin
- Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic LeukemiaCompletedPhase 2National Cancer Institute (NCI)NCT00025038Written as isotretinoin
- Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With NeuroblastomaCompletedPhase 1National Cancer Institute (NCI)NCT00005576Written as isotretinoin
- Vitamin E in Preventing the Side Effects of Isotretinoin in Former and Current Smokers Who Are Receiving Isotretinoin to Prevent Lung CancerWithdrawnPhase 3M.D. Anderson Cancer CenterNCT00003599Written as Isotretinoin
As the comparator · 5 — what is tested is compared with Isotretinoin
- Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe AcneRecruitingNot applicableSun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT06378983Written as Oral isotretinoin
- Efficacy & Safety Comparison of Epiduo With Doxycycline Versus Vehicle With Isotretinoin in the Treatment of Severe AcneCompletedPhase 3Galderma R&DNCT01474590Written as Isotretinoin
- Efficacy and Safety of Painless 5-aminolevulinic Acid Photodynamic Therapy for Moderate and Severe Acne VulgarisStatus unknownNot applicableShanghai Dermatology HospitalNCT04167982Written as Oral low-dose isotretinoin
- Efficacy and Safety of CIP-Isotretinoin in Patients With Severe Recalcitrant Nodular AcneCompletedPhase 3Cipher Pharmaceuticals Inc.NCT00975143Written as Isotretinoin
- A Study of MAb-3F8 Plus Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Versus 13-cis-Retinoic Acid (RA) Plus GM-CSF in Primary Refractory Neuroblastoma PatientsTerminatedPhase 2United TherapeuticsNCT00969722Written as 13-cis-Retinoic Acid
Codes
What other systems call Isotretinoin · ClinicalTrials.gg INT008470
- MeSH (NLM) D015474IsotretinoinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) EH28UP18IFISOTRETINOINConfirmed FDA, NLM, Wikidata
- RxNorm 6064Confirmed FDA, Wikidata
- Wikidata Q287029isotretinoinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C603IsotretinoinOne source FDA
- DrugBank DB00982One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015474 | Isotretinoin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | EH28UP18IF | ISOTRETINOIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6064 | — | Confirmed FDA, Wikidata |
| Wikidata | Q287029 | isotretinoin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C603 | Isotretinoin | One source FDA |
| DrugBank | DB00982 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.