Drug
Dorzolamide-timolol combination clinical trials
- studies test it
- 16
- open now
- 0
- in phase 3
- 2
- first study started
- 2005
How studies write it
Studies that test it under each name
Development codes
Combined with it in one product
Studies by the year they started
16 studies that test it; most in 2006 (4)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2006 | 4 |
| 2007 | 1 |
| 2008 | 3 |
| 2009 | 3 |
| 2010 | 1 |
| 2011 | 1 |
| 2015 | 1 |
| 2017 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 2
- 5
- Phase 3
- 2
- Phase 4
- 8
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 8
Merck Sharp & Dohme LLC (3) · Wills Eye (2) · Alcon Research (2) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1) · Laboratorios Sophia S.A de C.V. (1) · Allergan (1) · University of Michigan (1) · West Virginia University (1)
Often tested with
Tested in the same studies.
Latanoprost (2) · Xalacom (1) · Brimonidine Tartrate, Timolol Maleate Drug Combination (1) · Dorzolamide (1) · Timolol (1) · Prostaglandins (1) · Azarga (1) · Brinzolamide (1)
Studies
Open first, then newest update. How each study uses dorzolamide-timolol combination is read from its arms, and is right about nine times in ten.
Testing it · 16
- A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ GlaucomaCompletedPhase 4Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00140049Written as Cosopt
- Dorzolamide-timolol in Combination With Anti-vascular Endothelial Growth Factor Injections for Wet Age-related Macular DegenerationCompletedPhase 2/3Wills EyeNCT03034772Written as Dorzolamide-timolol
- Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME.CompletedPhase 2Wills EyeNCT02571972Written as Dorzolamide-timolol
- Clinical Study of A Fixed Combination of Timolol-Brimonidine-DorzolamideCompletedPhase 2Laboratorios Sophia S.A de C.V.NCT01062971Written as dorzolamide-timolol-brimonidine
- Comparing Effects of Two Fixed Combinations Ophthalmic Solutions on Ocular Blood FlowCompletedPhase 4AllerganNCT00811850Written as fixed combination of dorzolamide hydrochloride timolol maleate ophthalmic solution
- COSOPT (Timolol/Dorzolamide Combination) Normal Tension Glaucoma Study (MK0507A-161)(COMPLETED)CompletedPhase 2Merck Sharp & Dohme LLCNCT00832377Written as timolol/dorzolamide combination
- Dry Eye Study With Cosopt® Over 8 Weeks in Patients With Open-Angle Glaucoma or Ocular Hypertension (0507A-152)(COMPLETED)CompletedPhase 4Merck Sharp & Dohme LLCNCT00545064Written as dorzolamide hydrochloride (+) timolol maleate
- Effect of Myocilin Genetic Variants on Intraocular Pressure and Pressure Variation in Sitting and Supine PositionsCompletedPhase 4University of MichiganNCT00906087Written as Cosopt (combination eyedrop of dorzolamide and timolol)
- A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153)CompletedPhase 3Merck Sharp & Dohme LLCNCT00546286Written as dorzolamide hydrochloride (+) timolol maleate
- Patient Preference Comparison of AZARGA Versus COSOPT in Patients With GlaucomaCompletedPhase 4Alcon ResearchNCT01471158Written as Dorzolamide/timolol Maleate Fixed Combination (COSOPT)
- 12-Month Stability of Diurnal IOP Control on CosoptCompletedPhase 4West Virginia UniversityNCT00379834Written as Cosopt
- Safety Study of Aqueous Suppression After Ahmed Glaucoma Valve (AGV) ImplantationStatus unknownPhase 2Zahra Rabbani KhahNCT01814514Written as Timolol-trusopt
- Safety and Efficacy of Brinzolamide Dosed TID With Dorzolamide Dosed TID in Reducing Intraocular Pressure in Patients With Open Angle Glaucoma or Ocular HypertensionCompletedPhase 4Alcon ResearchNCT00761995Written as Cosopt
- The Effects of Cosopt® Vs Xalacom® on Ocular Hemodynamics and Intraocular Pressure (IOP) in Primary Open-angle Glaucoma (POAG)WithdrawnNot applicableMeir Medical CenterNCT00815373Written as Dorzolamide+Timolol Maleate0.5%
- Effects of Cosopt on IOP and on Ocular Diastolic Perfusion PressureStatus unknownPhase 4University of Turin, ItalyNCT00796198Written as Xalatan+Cosopt
- Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.Status unknownNot applicableAdvanced Glaucoma SpecialistsNCT00440336Written as Cosopt
As the comparator · 8 — what is tested is compared with dorzolamide-timolol combination
- Efficacy and Safety of DNN.31.19.026 for Ocular Hypertension or Primary Open-Angle GlaucomaNot yet recruitingPhase 3Ache Laboratorios Farmaceuticos S.A.NCT07617532Written as COSOPT®
- A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular HypertensionNot yet recruitingPhase 2Kukje PharmaNCT06177678Written as COSOPT ophthalmic solution
- Comparative Study of Dorzotimol Eye Drops, 20 mg/mL + 5 mg/mL Versus Cosopt® Eye Drops, 20 mg/mL + 5 mg/mLCompletedPhase 3Jadran Galenski laboratorij d.d.NCT05973318Written as Cosopt eye drops, 20 mg/mL + 5 mg/mL
- A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular HypertensionCompletedPhase 3Alcon ResearchNCT00333125Written as Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (Cosopt)
- A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular HypertensionCompletedPhase 3Alcon ResearchNCT00314171Written as Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)
- Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular HypertensionCompletedPhase 4Alcon ResearchNCT01111890Written as Cosopt (dorzolamide 2% / timolol 0.5%)
- 1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPTTerminatedPhase 3Alcon ResearchNCT00767481Written as Cosopt
- Study of Travatan and Cosopt in Primary Open-Angle Glaucoma or Ocular HypertensionTerminatedPhase 4Alcon ResearchNCT00471068Written as Cosopt