Retinal Detachment clinical trials
The registry lists 199 studies for Retinal Detachment across more than 10 countries. 29 are recruiting or about to start. 146 of them are mainly about Retinal Detachment (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Status
Who runs them
Minia University (6) · Benha University (6) · Unity Health Toronto (6) · Centre Hospitalier Universitaire Dijon (5) · Wills Eye (4) · Central Hospital, Nancy, France (4) · Sun Yat-sen University (3) · Sohag University (3)
What is being tested here
Drugs under test in Retinal Detachment studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Angiogenesis inhibitors 14 · Corticosteroids 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- May 2027Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery · Phase 3 · Hopital Foch
- Dec 20261ry Versus 2ry ILM Peeling in RD · Sohag University
- Dec 2026Spring Loaded Syringe for Active Silicon Oil Extraction · Sohag University
- Dec 2026Intraoperative OCT Guidance of Intraocular Surgery II · Duke University
- Jan 2027Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment · Fondazione G.B. Bietti, IRCCS
- Jun 2027Surgical Procedure Efficiency Evaluation stuDy · Alcon Research
- Jul 2027REtinal Detachment Outcomes Study · CHU de Quebec-Universite Laval
- Jul 2027High Resolution, High-speed Multimodal Ophthalmic Imaging · Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
- Oct 2027Influence of Perfluorocarbon Liquid (LIQUID) During Pars Plana Vitrectomy on Retinal Vessel Displacement in Primary Macula-involving Rhegmatogenous Retinal Detachment · Norfolk and Norwich University Hospitals NHS Foundation Trust
- Oct 2027Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment · Center for Eye Research Australia
Who these studies take
Of the 21 Retinal Detachment studies recruiting now, 15 (71%) set no upper age limit and 4 (19%) stop at 75 or younger. 3 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (14%) | 3 (14%) |
| 18 | 19 (90%) | 19 (90%) |
| 30 | 20 (95%) | 20 (95%) |
| 40 | 20 (95%) | 20 (95%) |
| 50 | 21 (100%) | 21 (100%) |
| 65 | 21 (100%) | 21 (100%) |
| 75 | 17 (81%) | 17 (81%) |
| 85 | 17 (81%) | 17 (81%) |
Across all 199 studies, recruiting or not: 20% stop at 75 or younger and 12% at 65; 21% take children; 0% are for women only and 0% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Retinal Detachment studies take
Of 56 interventional studies with no phase under Retinal Detachment, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 23 mo12–49 · 56 studies | — | 23 mo12–49 · 55 studies |
| Observational | 33 mo9–42 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 199. Browse all 199 → or search them.
- REtinal Detachment Outcomes StudyRecruitingNCT05863312Not applicable1 country
- Surgical Procedure Efficiency Evaluation stuDyRecruitingNCT072280911 country
- Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS)RecruitingNCT07146516Not applicable1 country
- Intraoperative OCT Guidance of Intraocular Surgery IIRecruitingNCT037132681 country
- OCT Macula Biomarkers Before Silicone Oil Removal and Visual Outcome After Silicone Oil RemovalNot yet recruitingNCT07865468
- Use of Preoperative Gas in Eyes With Macula-off Rhegmatogenous Retinal Detachment (RRD)Not yet recruitingNCT07855770Phase 2/31 country
- Reliability of Optical and Ultrasound Biometry in Silicon Filled EyesRecruitingNCT077319841 country
- Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal DetachmentRecruitingNCT07500324Not applicable1 country
- Effect of Silicon Oil on Retinal Electrical Functions Using Multifocal ElectroretinogramRecruitingNCT07609628Not applicable1 country
- Influence of Perfluorocarbon Liquid (LIQUID) During Pars Plana Vitrectomy on Retinal Vessel Displacement in Primary Macula-involving Rhegmatogenous Retinal DetachmentRecruitingNCT07027098Not applicable1 country
- Nicotinamide Riboside Oral Supplementation in Macula Off Retinal DetachmentRecruitingNCT06587945Phase 41 country
- Spring Loaded Syringe for Active Silicon Oil ExtractionRecruitingNCT07363889Not applicable1 country
- 1ry Versus 2ry ILM Peeling in RDRecruitingNCT07346560Not applicable1 country
- Acute Retinal Detachment Repair With the iSeelr™ Retinal Detachment Repair SystemRecruitingNCT06468397Not applicable1 country
- Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal DetachmentNot yet recruitingNCT07034469Not applicable
- High Resolution, High-speed Multimodal Ophthalmic ImagingRecruitingNCT04129021Not applicable1 country
- Animated Video Education for Retinal SurgeryNot yet recruitingNCT07184255Not applicable1 country
- hAM for Inferior RRDRecruitingNCT07081945Not applicable1 country
- Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment SurgeryRecruitingNCT06294847Phase 31 country
- Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with Silicone Oil Tamponade in Retinal Detachment PatientsRecruitingNCT068265731 country
- Intravitreal Topotecan in the Repair of Rhegmatogenous Retinal Detachment with Proliferative VitreoretinopathyRecruitingNCT05523869Phase 21 country
- Comparison of Anatomical and Functional Outcomes of Laser Photocoagulation and Cryopexy in Patients with Rhegmatogenous Retinal Detachment Treated with Pneumatic RetinopexyRecruitingNCT06694259Not applicable1 country
- Foldable Capsular Scleral Buckling Versus Vitrectomy in Medium-complex Rhegmatogenous Retinal Detachment TreatmentNot yet recruitingNCT06610786Not applicable1 country
- Caffeine and Cataract After Pars Plana VitrectomyRecruitingNCT06358664Not applicable1 country
- Comparative Study Between Three Different Techniques in Drainage of SRF During PPV in RRDNot yet recruitingNCT06324305Not applicable
- Clinical Characteristics and Surgical Outcomes of the Fellow Eye in Bilateral Retinal DetachmentsNot yet recruitingNCT062925721 country
- "Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy"RecruitingNCT06289205Phase 1/21 country
- Multimodal Imaging in Vitreo-retinal Surgery and Macular DystrophiesRecruitingNCT057471441 country
- Internal Limiting Membrane Peeling in Retinal Detachment SurgeryNot yet recruitingNCT05538156Not applicable
- Artificial Intelligence-Assisted Lesion-Based Urgent Referral Triage of Ultra-Widefield Retinal ImagesCompletedNCT07643129Not applicable1 country
- Anatomical and Functional Outcomes of Pneumatic Retinopexy for Retinal Detachment: A 2-Year Case SeriesCompletedNCT077941631 country
- DISCOVER Study: Microscope-integrated Intraoperative OCT StudyCompletedNCT024232131 country
- Corneal Endothelial Cell Changes In Silicon Filled EyeActive, not recruitingNCT074186061 country
- Scleral Buckling for Retinal Detachment Prevention in Genetically Confirmed Stickler SyndromeWithdrawnNCT04465188Phase 21 country
- Peeling of the Internal Limiting Membrane During Primary Vitrectomy for Retinal Detachment RepairTerminatedNCT07438210Not applicable1 country
- Influence of Tamponade on Retinal Shift in Eyes Undergoing Vitrectomy for Rhegmatogenous Retinal Detachment: A Comparison of Gas Versus Silicone Oil in a Pakistani PopulationCompletedNCT07495319Not applicable1 country
- Early VItrectomy in DENse Spontaneous Vitreous HEmorrhageCompletedNCT04676256Not applicable1 country
- DOREFA (Retinal Detachment: Function and Anatomy)CompletedNCT01767038Not applicable1 country
- Study of Vitreoretinal Molecular Changes During Rhegmatogenous Retinal DetachmentCompletedNCT06347302Not applicable1 country
- Impact of ILM Peeling in RRD/ I-PeelActive, not recruitingNCT04767555Not applicable1 country
- Suprachoroidal Visco-buckling for the Treatment of Rhegmatogenous Retinal DetachmentCompletedNCT04557527Not applicable1 country
- Methotrexate in Retinal Detachment With Proliferative VitreoretinopathyCompletedNCT07058337Not applicable1 country
- The GUARD Trial - Part 1: A Phase 3 Clinical Trial for Prevention of Proliferative VitreoretinopathyCompletedNCT04136366Phase 31 country
- A Study of Fluoroquinolones Exposure and Collagen-Related Serious Adverse EventsCompletedNCT034797361 country
- Head Position Monitoring After Pars Planar VitrectomyActive, not recruitingNCT069850301 country
- Perfluorocarbon Liquid vs. Posterior Retinotomy During Pars-plana Vitrectomy for Rhegmatogenous Retinal DetachmentCompletedNCT06919211Not applicable1 country
- Subjective Pain Scoring for Subtenonal Anesthesia During VitrectomyActive, not recruitingNCT068300701 country
- Outcomes of Retinal Re-surgeries in Silicone Oil Filled EyesCompletedNCT065837981 country
- A Study to Evaluate the Safety and Tolerability of ONL1204 in Patients With Macula-off, Rhegmatogenous Retinal DetachmentCompletedNCT03780972Phase 11 country
- Lamivudine and Plasma Markers of Inflammation in Retinal DetachmentTerminatedNCT06056596Early Phase 11 country