Dextromethorphan: all 91 studies that test it

Page 1 of 1. Open to participants first (10), then studies with results posted, then the rest; newest registration first within each.

• Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic SurgeryRecruitingNCT07860203Not applicable
• Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive DisorderNot yet recruitingNCT07593222Phase 1/2
• Nintedanib With or Without Dextromethorphan in Patients With Idiopathic Pulmonary Fibrosis (IPF)Not yet recruitingNCT07583589Phase 2
• A Study of Psychedelics in Healthy Older Adults With Low Well-beingRecruitingNCT07386730Phase 1
• Clinical Trial to Investigate the Safety and Efficacy of Two Dexamfetamine Sulfate Formulations in Adults With ADHD and Moderate to Severe DepressionRecruitingNCT06967857Phase 2
• Investigation of Psychedelic Effects in Psychoactive SubstancesRecruitingNCT06772753Phase 1
• Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail ApproachRecruitingNCT06693960Early Phase 1
• DEX vs SEVO in Congenital Heart SurgeryNot yet recruitingNCT05369949Phase 4
• Dextromethorphan for Treatment of Postoperative PainRecruitingNCT05278494Not applicable
• Study of Dextromethorphan in OCD and Related DisordersRecruitingNCT04899687Phase 2
• Impact of Nuedexta on Bulbar Physiology and Function in ALSCompletedNCT03883581Phase 1/2Results posted
• Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's DiseaseCompletedNCT03854019Phase 3Results posted
• A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric PatientsCompletedNCT03714919Phase 2Results posted
• Dextromethorphan in FibromyalgiaCompletedNCT03538054Phase 2Results posted
• Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication AbortionCompletedNCT03480009Phase 3Results posted
• Study of SHP620 (Maribavir) in Healthy AdultsCompletedNCT02775240Phase 1Results posted
• A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the BodyCompletedNCT02688088Phase 1Results posted
• Dextromethorphan Pediatric Acute Cough StudyTerminatedNCT02651116Phase 4Results posted
• Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)TerminatedNCT02496039Phase 4Results posted
• Efficacy Study of Dextromethorphan to Treat Rheumatoid ArthritisCompletedNCT02368093Not applicableResults posted
• Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical TrialCompletedNCT02218203Phase 2Results posted
• Nuedexta for the Prevention and Modification of Disease Progression in Episodic MigraineCompletedNCT02176018Phase 2Results posted
• Histamine Glutamate Antagonism in StrokeCompletedNCT02142712Phase 2Results posted
• Dexamethasone Plus Virtual Reality Exposure Therapy for PTSDCompletedNCT01965366Phase 4Results posted
• Nuedexta in Treatment-Resistant Major DepressionCompletedNCT01882829Phase 2Results posted
• Clinical Trial Nuedexta in Subjects With ALSCompletedNCT01806857Phase 2Results posted
• Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA)CompletedNCT01799941Phase 4Results posted
• Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy VolunteersCompletedNCT01766050Phase 4Results posted
• Nuedexta for the Treatment of Adults With AutismCompletedNCT01630811Phase 2Results posted
• Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's DiseaseCompletedNCT01584440Phase 2Results posted
• Placebo Controlled Trial of Dextromethorphan in Rett SyndromeCompletedNCT01520363Phase 2Results posted
• Dextromethorphan for Diabetic Macular EdemaCompletedNCT01441102Phase 1/2Results posted
• Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical TrialCompletedNCT01435798Phase 2Results posted
• Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple SclerosisCompletedNCT01324232Phase 2Results posted
• Acute Cough Study In ChildrenTerminatedNCT01257542Phase 4Results posted
• A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic MelanomaCompletedNCT01001299Phase 1Results posted
• Trial of Dextromethorphan in Rett SyndromeTerminatedNCT00593957Phase 2Results posted
• Safety and Efficacy of AVP-923 in PBA Patients With ALS or MSCompletedNCT00573443Phase 3Results posted
• Interscalene Nerve Blocks With Ropivacaine Alone, With Dexamethasone, Plus Systemic DexamethasoneTerminatedNCT00519584Not applicableResults posted
• A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal OutcomeCompletedNCT00201643Phase 4Results posted
• A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy ParticipantsCompletedNCT07241065Phase 1
• Dexmedetomidine Versus Midazolam for Peribulbar BlockCompletedNCT06784843Not applicable
• A Study Evaluating the Potential of BMS-984923 to Alter the Systemic Exposure of Three Orally Administered Probe SubstratesActive, not recruitingNCT06632990Phase 1
• Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Saddle BlockCompletedNCT06216197Not applicable
• Dextromethorphan as an Augmentation Agent in Treatment-resistant SchizophreniaCompletedNCT05944510Phase 4
• A Study of IBI351 in Healthy SubjectsCompletedNCT05699993Phase 1
• Conscious Sedation for Transcatheter Aortic Valve ImplantationCompletedNCT05462938Not applicable
• Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and DolutegravirCompletedNCT05236530Phase 1
• Repurposing of Dextromethorphan as an Adjunct Therapy in Patients With Major Depressive DisorderCompletedNCT05181527Phase 4
• Dextromethorphan Added on for Children With Chronic IrritabilityCompletedNCT05043805Phase 4
• Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex NeuroplasticityActive, not recruitingNCT04923659Early Phase 1
• Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine AddictionStatus unknownNCT04687566Phase 2/3
• Study of AO-176 as Monotherapy and in Combination With Bortezomib/Dexamethasone in Relapsed/Refractory Multiple MyelomaCompletedNCT04445701Phase 1/2
• Three Dosing Regimens of Dextromethorphan (DXM) Reportedly Used in Major Depressive DisorderCompletedNCT04226352Phase 1
• Add-on Low Dose Dextromethorphan and Memantine in Patients With Amphetamine-type Stimulants Use DisorderCompletedNCT03729128Phase 1/2
• Drug Interaction Study of CT1812 in Healthy VolunteersCompletedNCT03716427Phase 1
• Risk Prediction of Dexmedetomidine-associated Hemodynamic InstabilitySuspendedNCT03285087Phase 2/3
• Combination of Dextromethorphan and Memantine in Treating Bipolar DisorderStatus unknownNCT03039842Phase 3
• Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee ArthroplastyTerminatedNCT02987920Phase 4
• A Trial of Dextromethorphan for Treatment of Major Depressive DisorderCompletedNCT02860962Phase 1
• Does Pre and Postoperative Dextromethorphan Reduce Post-tonsillectomy Pain in Children?CompletedNCT02727491Phase 4
• Dexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery in InfantsCompletedNCT02559102Phase 3
• Dextromethorphan in Chemotherapy-induced Peripheral Neuropathy ManagementTerminatedNCT02271893Phase 2
• A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate CancerCompletedNCT02225093Phase 1
• Cortical Metrics in Intervention Trials With Autism Spectrum DisordersWithdrawnNCT02212275Phase 2/3
• Preop Dexmedetomidine Attenuates Haemodynamic Responses to HydrodissectionCompletedNCT02102139Phase 4
• Dexmedetomidine for Catheter-related Bladder DiscomfortStatus unknownNCT01991223Phase 4
• A Study to Investigate the Glucose Lowering Effects of Dextromethorphan Alone or in Combination With Sitagliptin in Subjects With Type 2 Diabetes Mellitus (T2DM) After an Oral Glucose Tolerance TestCompletedNCT01936025Phase 2
• Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer's DiseaseTerminatedNCT01832350Phase 4
• Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood SpotCompletedNCT01731067Phase 1
• Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult SubjectsCompletedNCT01651325Phase 1
• Study of NMDA Antagonists and Neuropathic PainCompletedNCT01602185Phase 2
• Lenalidomide and Low Dose Dexamethasone Versus Bortezomib, Lenalidomide and Low Dose Dexamethasone for Induction, in Patients With Previously Untreated Multiple MyelomaCompletedNCT01530594Phase 3
• Combined Therapy of Methadone and DextromethrophanStatus unknownNCT01189097Phase 3
• Add-On Therapy to Risperidonein SchizophreniaCompletedNCT01189006Phase 2/3
• Add-on Dextromethorphan in Bipolar DisordersCompletedNCT01188265Phase 3
• Dextromethorphan and Silymarin in Chronic Kidney Disease (CKD) PatientsStatus unknownNCT01091324Phase 3
• A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of DextromethorphanCompletedNCT00788047Phase 1
• Vascular Endothelial Protection Effects of DextromethorphanCompletedNCT00605605Phase 4
• Assessment of Opioid Analgesia in Sickle CellWithdrawnNCT00513864Phase 4
• Hyperalgesia in Methadone Patients: Can it be Treated?Status unknownNCT00333242Phase 1
• Hepatic Drug Biotransformation in Children With Obstructive Sleep ApneaCompletedNCT00310323Not applicable
• A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate NeurotoxicityTerminatedNCT00176553Not applicable
• Dextromethorphan in Treating Patients With Fatigue Caused by CancerTerminatedNCT00176540Not applicable
• Effect of Honey and Dextromethorphan on Nocturnal Cough and SleepCompletedNCT00127686Phase 1
• Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett SyndromeStatus unknownNCT00069550Phase 3
• Dextromethorphan to Treat Patients With Voice SpasmsCompletedNCT00055549Phase 1
• Studies of Dextromethorphan and Topiramate to Treat Oral and Facial PainCompletedNCT00001725Phase 2
• Dextromethorphan for the Treatment of Parkinson's Disease and Similar Conditions of the Nervous SystemCompletedNCT00001365Phase 2
• Dextromethorphan Versus Placebo for Neuropathic PainCompletedNCT00001344Phase 2
• Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1CompletedNCT00000352Phase 2

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