Mycobacterium avium-intracellulare Infection clinical trials
The registry lists 66 studies for Mycobacterium avium-intracellulare Infection across more than 10 countries. 8 are recruiting or about to start. 51 of them are mainly about Mycobacterium avium-intracellulare Infection (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (18) · Pharmacia (6) · Pfizer (6) · The University of Texas Health Science Center at Tyler (3) · Insmed Incorporated (2) · Spero Therapeutics (2) · Taipei Veterans General Hospital, Taiwan (1) · Mannkind Corporation (1)
What is being tested here
Drugs under test in Mycobacterium avium-intracellulare Infection studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Mar 2027IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study) · Chris Goss
- Oct 2027Hypertonic Saline Inhalation for Mycobacterium Avium Complex Pulmonary Disease · Radboud University Medical Center
Who these studies take
Of the 7 Mycobacterium avium-intracellulare Infection studies recruiting now, 6 (86%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (14%) | 1 (14%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 7 (100%) | 7 (100%) |
Across all 66 studies, recruiting or not: 11% stop at 75 or younger and 11% at 65; 35% take children; 5% are for women only and 0% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 66. Browse all 66 → or search them.
- Study of Mycobacterial InfectionsRecruitingNCT000180441 country
- Hypertonic Saline Inhalation for Mycobacterium Avium Complex Pulmonary DiseaseRecruitingNCT05192057Phase 41 country
- Hypertonic Saline Inhalation for Nontuberculous Mycobacterial Lung DiseaseRecruitingNCT07647575Not applicable1 country
- Safety, Immunogenicity, and Efficacy of Therapeutic Mycobacterium Bovis BCG (BOOST)RecruitingNCT07094711Phase 21 country
- Clinical Characteristics and Immune Escape Mechanism of Nontuberculous Mycobacterial Lung Disease in South ChinaNot yet recruitingNCT07377864
- IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)RecruitingNCT04294043Phase 11 country
- M. Avium WGS During Mav-PD TreatmentRecruitingNCT062664421 country
- Drug Exposure and Minimum Inhibitory Concentration in the Treatment of MAC Lung DiseaseRecruitingNCT058249881 country
- A Study of Standard Drugs for Mycobacterium Avium ComplexCompletedNCT04287049Phase 21 country
- Study of Epetraborole in Patients With Treatment-refractory MAC Lung DiseaseTerminatedNCT05327803Phase 2/34 countries
- Clofazimine in the Treatment of Pulmonary Mycobacterium Avium Complex (MAC)Active, not recruitingNCT02968212Phase 21 country
- Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium ComplexCompletedNCT04677569Phase 323 countries
- Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex DiseaseCompletedNCT03672630Phase 2/32 countries
- Evaluation of Sevoflurane Consumption During Initial Phase of Minimal-Flow Anesthesia in Retrograde Intrarenal SurgeryCompletedNCT07248917Not applicable1 country
- ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation SuspensionTerminatedNCT06418711Phase 35 countries
- Haploidentical BMT With Post-Transplant Cyclophosphamide and BendamustineCompletedNCT02996773Phase 11 country
- A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary DiseaseCompletedNCT05496374Phase 21 country
- Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium ComplexCompletedNCT04677543Phase 312 countries
- A Pilot Study to Assess the Effect of Intermittent iNO on the Treatment of NTM Lung Infection in CF and Non-CF PatientsCompletedNCT04685720Not applicable1 country
- Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary DiseaseTerminatedNCT04553406Phase 21 country
- Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDSCompletedNCT00001047Phase 31 country
- A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive PatientsCompletedNCT00000947Not applicable1 country
- A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.CompletedNCT00000641Phase 21 country
- A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDSCompletedNCT00001058Phase 22 countries
- The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected PatientsCompletedNCT00001030Phase 32 countries
- A Study to Evaluate the Effects of Interleukin-12 (rhIL-12) in HIV-Positive Patients With CD4 Cell Counts Less Than 50 Cells/mm3 or 300-500 Cells/mm3CompletedNCT00000857Phase 11 country
- Effects of MAC Preventive Therapy on Disease-Causing Bacteria in HIV-Infected Patients: A Substudy of CPCRA 048CompletedNCT000009331 country
- A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV InfectionCompletedNCT00000895Not applicable1 country
- Non-interventional Study With NOVOCART® Basic in Patients Treated for Cartilage Defects in the Knee With MACCompletedNCT038086232 countries
- A Drug Interaction Study Investigating the Effect of Rifabutin on the Pharmacokinetics of MaravirocCompletedNCT01894776Phase 11 country
- Adjuvant Cytokine Therapy to Treat Pulmonary Mycobacterium Avium Complex InfectionCompletedNCT00111397Phase 11 country
- Clarithromycin for the Treatment of Infections Caused by Nontuberculous Mycobacteria (NTM)CompletedNCT00600769Phase 41 country
- Effectiveness of Rifabutin in the Treatment of Mycobacterium Avium ComplexCompletedNCT03164291Phase 31 country
- Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung DiseaseCompletedNCT00598962Phase 41 country
- Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung DiseaseCompletedNCT027790491 country
- Phase II Study of Amithiozone (Thiacetazone) for Patients With Mycobacterium Avium Complex Pulmonary DiseaseCompletedNCT00004689Phase 2
- Improving Tolerance of Treatment of Pulmonary MAC InfectionsWithdrawnNCT01719042Phase 2
- The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected PatientsCompletedNCT00001023Not applicable1 country
- Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected PatientsCompletedNCT00001039Phase 21 country
- Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV TherapyCompletedNCT00000883Not applicable1 country
- Mycobacterium Avium Intracellulare Complex (MAC) StudyCompletedNCT008264231 country
- A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDSCompletedNCT00000644Phase 21 country
- The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDSCompletedNCT00000971Phase 11 country
- A Study to Examine the Effects of Stopping Preventive Therapy for Disseminated Mycobacterium Avium Complex (DMAC) in HIV-Positive PatientsCompletedNCT000009071 country
- Clofazamine for the Treatment of Mycobacterium Avium Intracellulare(MAI)CompletedNCT00652067
- Subcutaneously Administered Interleukin-12 Therapy in HIV-Infected Patients With Disseminated Mycobacterium Avium Complex InfectionCompletedNCT00001763Phase 11 country
- A Randomized, Double-Blinded, Placebo-Controlled, Phase II Inhaled Interferon Gamma-1b and Antimycobacterials to Treat Pulmonary Mycobacterium Avium Complex InfectionsCompletedNCT00021567Phase 21 country
- Safety and Efficacy of Inhaled Interferon Gamma-1b in Pulmonary MAC InfectionTerminatedNCT00043355Phase 2
- Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled TrialCompletedNCT00002267Not applicable2 countries
- Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIVCompletedNCT00002104Phase 11 country