Cryptosporidiosis clinical trials
The registry lists 32 studies for Cryptosporidiosis across more than 10 countries. 6 are recruiting or about to start. 26 of them are mainly about Cryptosporidiosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (7) · Novartis Pharmaceuticals (3) · Romark Laboratories L.C. (2) · Pfizer (2) · Rhone-Poulenc Rorer (2) · Janssen, LP (2) · Sohag University (1) · Univax Biologics Inc (1)
What is being tested here
Drugs under test in Cryptosporidiosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Nitazoxanide | 1 | 2 | 5 |
| Echinacea extract | 1 | 0 | 1 |
| Azithromycin | 0 | 0 | 3 |
| Paromomycin | 0 | 0 | 2 |
| Spiramycin | 0 | 0 | 2 |
| Interleukin-12 | 0 | 0 | 2 |
| Clofazimine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Mar 2027Study Testing the Efficacy, Safety, and Tolerability of EDI048 in Cryptosporidium Infection Model in Healthy Adults · Novartis Pharmaceuticals
- May 2027A Study to Characterize the Clinical Presentation and Course of Cryptosporidium in Pediatric Participants · Novartis Pharmaceuticals
Who these studies take
Of the 4 Cryptosporidiosis studies recruiting now, 1 (25%) set no upper age limit and 3 (75%) stop at 75 or younger. 3 (75%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (50%) | 2 (50%) |
| 18 | 2 (50%) | 2 (50%) |
| 30 | 2 (50%) | 2 (50%) |
| 40 | 2 (50%) | 2 (50%) |
| 50 | 2 (50%) | 2 (50%) |
| 65 | 1 (25%) | 1 (25%) |
| 75 | 1 (25%) | 1 (25%) |
| 85 | 1 (25%) | 1 (25%) |
Across all 32 studies, recruiting or not: 44% stop at 75 or younger and 44% at 65; 72% take children; 0% are for women only and 0% for men only; 22% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 15, 2026.
Stopped1
- Cryptosporidium Infection and Human Colorectal CancerTerminatedNov 6, 2026NCT04332705
Studies
Recruiting first, then most recently updated. Showing 32 of 32. search them.
- Study Testing the Efficacy, Safety, and Tolerability of EDI048 in Cryptosporidium Infection Model in Healthy AdultsRecruitingNCT07249463Phase 21 country
- Nitazoxanide for Treatment of Cryptosporidium in ChildrenNot yet recruitingNCT06600711Phase 3
- A Study to Characterize the Clinical Presentation and Course of Cryptosporidium in Pediatric ParticipantsRecruitingNCT077164103 countries
- The Effect of Echinacea (Immulant ®) in the Treatment of CRYPTOSPORIDIOSIS in Immunocompromised ChildrenRecruitingNCT07388615Phase 21 country
- Blastocystis and Cryptosporidium Infection in Colorectal Cancer PatientsNot yet recruitingNCT06379035
- Cryptosporidium Species in Sohag GovernorateRecruitingNCT052089701 country
- Cryptosporidium Infection and Human Colorectal CancerTerminatedNCT043327051 country
- Cryptosporidiosis and Enteropathogens in BangladeshActive, not recruitingNCT027649181 country
- Study of Efficacy and Safety of ABO809 in Healthy ParticipantsCompletedNCT05036668Phase 11 country
- Treatment of CryptosporidiosisCompletedNCT04103216Not applicable1 country
- A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3CompletedNCT00000771Phase 22 countries
- A Study of Nitazoxanide in Patients With AIDS and Diarrhea Caused by CryptosporidiumCompletedNCT00001081Phase 21 country
- Nitazoxanide for the Treatment of Chronic Diarrhea in HIV Infected ChildrenCompletedNCT00055107Phase 1/22 countries
- Intestinal Parasites in Inhabitants of Kuyavian-Pomeranian Province in PolandCompletedNCT034904351 country
- A Phase 2A Evaluation of the Safety, Tolerability, Pharmacokinetics, Efficacy of Clofazimine (CFZ) in CryptosporidiosisTerminatedNCT03341767Phase 21 country
- Breast Milk Composition and HIV-exposed/Unexposed Early Infant Growth and Infectious Disease EventsCompletedNCT016998411 country
- Parasitic Infections of the Gastrointestinal TractTerminatedNCT000011621 country
- Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in KenyaCompletedNCT01695304Not applicable1 country
- Treatment of Chronic Cryptosporidiosis in AIDS PatientsTerminatedNCT00001128Not applicable1 country
- Interleukin 12 (IL-12) for the Treatment of Cryptosporidiosis in AIDS PatientsTerminatedNCT00057486Phase 1/2
- Transmission and the Respiratory Tract in CryptosporidiosisCompletedNCT005078711 country
- A Study to Evaluate the Use of Nitazoxanide to Treat CryptosporidiosisStatus unknownNCT00002158Not applicable1 country
- The Effectiveness of Cow's Milk Immune Globulin in the Treatment of AIDS-Related DiarrheaCompletedNCT00002264Not applicable1 country
- A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDSCompletedNCT00002278Not applicable1 country
- Azithromycin in the Treatment of Cryptosporidiosis in Patients Who Have Not Had Success With Other DrugsCompletedNCT00002328Not applicable1 country
- A Study of Letrazuril in the Treatment of AIDS-Related DiarrheaCompletedNCT00001018Phase 11 country
- A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Trial of the Efficacy and Safety of Bovine Anti-Cryptosporidium Immunoglobulin (BACI) in the Treatment of Cryptosporidium Enteritis in AIDS PatientsCompletedNCT00002248Phase 11 country
- A Study of Spiramycin in the Treatment of Patients With AIDS-Related DiarrheaCompletedNCT00000980Phase 11 country
- Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind StudyCompletedNCT00002082Not applicable1 country
- Protocol For the Treatment of Cryptosporidiosis in AIDS Patients With Diclazuril (R64,433)CompletedNCT00002027Not applicable1 country
- Safety and Effectiveness of Nitazoxanide for the Treatment of Cryptosporidiosis in AIDS PatientsTerminatedNCT00004986Phase 31 country
- Open-Label "Compassionate" Use Study of Spiramycin for the Treatment of Diarrhea Due to Chronic Cryptosporidiosis in Immunocompromised PatientsCompletedNCT00002062Not applicable1 country