Adrenergic alpha-Agonists: all 451 studies that test it

Page 1 of 5. Open to participants first (88), then studies with results posted, then the rest; newest registration first within each.

• OB VEGA-Phenylephrine vs Norepinephrine OutcomesNot yet recruitingNCT07900919Phase 4
• ED90 of Norepinephrine and Phenylephrine Infusion in Patients of Advanced Maternal AgeNot yet recruitingNCT07894783Not applicable
• Low-Dose Norepinephrine With Conservative Fluid Therapy in Hepatobiliary SurgeryNot yet recruitingNCT07892586Not applicable
• ESP Blocks in Breast Free FlapsRecruitingNCT07891039Phase 1
• Pre-induction Norepinephrine in Septic Patients Undergoing SurgeryNot yet recruitingNCT07869693Not applicable
• Superiority of Phenylephrine Versus Norepinephrine in Complex Spine Surgery (SPiNeS)Not yet recruitingNCT07796282Phase 4
• Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate: Exploring Its Role in Optimizing Surgical OutcomesRecruitingNCT07733167Phase 3
• Split Face Study of the Duration of Local Anesthetics - Fifth ArmNot yet recruitingNCT07724418Phase 4
• 5 Versus 10 mcg Norepinephrine Bolus in Treatment of Postinduction and Early Intraoperative Hypotension in Emergency Abdominal SurgeryRecruitingNCT07719075Not applicable
• This is a Study That Aims to Estimate the Effect of Maternal Body Mass Index on the Prophylactic Dose of Norepinephrine Infusion for Preventing Hypotension in Parturient After Spinal AnesthesiaNot yet recruitingNCT07706426Not applicable
• Vasopressor Agents in Pulmonary Hypertension CrisisRecruitingNCT07667829Not applicable
• Comparison of Norepinehrine Versus Phenylepherine Infusion for Prevention of Post-spinal HypotensionRecruitingNCT07662408Phase 4
• Effects of Anisodamine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic ShockNot yet recruitingNCT07657702Not applicable
• Buffered Versus Conventional Local Anesthesia for Pain and Anxiety Reduction in School-Aged Children With PulpitisRecruitingNCT07638254Not applicable
• Phenotype Guided Vasoactive Medication During Kidney TransplantationEnrolling by invitationNCT07633600Phase 4
• PRO STRESS Trial: Proactive Low-Dose Norepinephrine to Reduce Intraoperative Fluid Administration in Patients at High-Risk for Postoperative Pulmonary Complications Undergoing Laparoscopic Abdominal SurgeryNot yet recruitingNCT07627360Not applicable
• Effect of Push-Dose Adrenaline on Peri-intubation Hypotension During Rapid Sequence Intubation in the Emergency DepartmentNot yet recruitingNCT07620327Phase 4
• Pre-emptive Local Anesthesia and Emergence Behavior After Pediatric Dental General AnesthesiaNot yet recruitingNCT07604337Not applicable
• Assessing Catecholamine Treatment Initiation Options: Norepinephrine vs Dopamine for Cardiogenic ShockRecruitingNCT07562932Not applicable
• Low-dose Norepinephrine Infusion for Prevention of Post-induction Hypotension in Emergency Surgery for PeritonitisNot yet recruitingNCT07529795Phase 4
• Impact of Low Dose Epinephrine in the Management of Out-of-hospital Cardiac Arrest on Neurological OutcomeNot yet recruitingNCT07442071Phase 3
• Early Co-Administration of Crystalloid Fluid and Norepinephrine for Preventing Acute Kidney Injury in Septic ShockNot yet recruitingNCT07418541Not applicable
• Intralesional Chemotherapy (IC): Cisplatin + EpinephrineRecruitingNCT07392580Phase 2
• Upneeq vs. Lumify PtosisNot yet recruitingNCT07390578Phase 4
• Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean DeliveryRecruitingNCT07379710Phase 4
• Dilute Epinephrine vs Tourniquet for Visualization in Ankle Arthroscopy: A RCTNot yet recruitingNCT07349407Not applicable
• Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)RecruitingNCT07322133Phase 4
• Adrenaline V/s Dopamine in Fuid Refractory Septic ShockRecruitingNCT07273526Not applicable
• Comparative PK/PD of FMXIN002 and EpiPen, in Healthy Adults With Allergic RhinitisEnrolling by invitationNCT07228325Phase 1/2
• Comparison of Milrinone and Epinephrine on TAPSERecruitingNCT07144267Not applicable
• Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee ArthroplastyNot yet recruitingNCT07097493Phase 4
• The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty SurgeryRecruitingNCT07089251Phase 4
• Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve GastrectomyNot yet recruitingNCT07084753Not applicable
• REctus Sheath TrialRecruitingNCT07068243Phase 2
• FMXIN002 in Patients at Risk of AnaphylaxisEnrolling by invitationNCT07045701Phase 2/3
• Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing, Immunotherapy or Oral ChallengesRecruitingNCT07038746Phase 1
• Early Norepinephrine in Trauma Patients With Hemorrhagic ShockEnrolling by invitationNCT06977659Phase 1/2
• An Outpatient Study of the Efficacy of ARS-2 in Patients With Chronic Spontaneous UrticariaRecruitingNCT06927999Phase 2
• The Investigator Administers Intracoronary Adrenaline Via the Catheter in STEMI Patients During Primary PCI, After Flow Restoration and Before Stenting, and Studies Its Effect in Prevention of No ReflowRecruitingNCT06847568Phase 3
• Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen ImmunotherapyRecruitingNCT06834165Phase 4
• Nasal Obstruction With Oxymetazoline and CorticosteroidsRecruitingNCT06830109Phase 2
• The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac SurgeryRecruitingNCT06802224Phase 4
• Early Neurovascular Adaptations in Aging WomenRecruitingNCT06520982Early Phase 1
• LIDRISE Study: A Phase 3 Study on the Efficacy and Safety of STN1013800 (Oxymetazoline HCl 0.1% Eye Drops, Single Dose) in the Treatment of Acquired Blepharoptosis.RecruitingNCT06514612Phase 3
• 10 Vs.15 mcg Norepinephrine Bolus in Severe Maternal Hypotension During Cesarean DeliveryNot yet recruitingNCT06512415Not applicable
• Epinephrine Vs Norepinephrine Infusion During Caesarean DeliveryNot yet recruitingNCT06512402Not applicable
• Norepinephrine on Maternal Hypotension After Combined Lumbar and Epidural AnaesthesiaRecruitingNCT06498115Phase 4
• Early Resuscitation in Paediatric Sepsis Using InotropesNot yet recruitingNCT06478797Phase 2
• Bupivacaine and Epinephrine Injection StudyRecruitingNCT06456255Phase 2/3
• Local Anesthesia for Facial FracturesRecruitingNCT06429501Phase 2
• Regional Lipolysis and Adipocyte Lipolysis Protein StimulationRecruitingNCT06416969Early Phase 1
• Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro StudyRecruitingNCT06285396Not applicable
• Timing of TAP Blocks in Bariatric SurgeryRecruitingNCT06270147Phase 2
• Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute BronchiolitisRecruitingNCT06267118Phase 3
• Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical TrialNot yet recruitingNCT06213935Not applicable
• ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment in Preeclamptic PatientsNot yet recruitingNCT06158035Not applicable
• 90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard TreatmentNot yet recruitingNCT06151522Not applicable
• 90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard TreatmentNot yet recruitingNCT06151509Not applicable
• Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension on Maternal HemodynamicsNot yet recruitingNCT06151496Not applicable
• 90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic PatientsNot yet recruitingNCT06151470Not applicable
• 90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment in Preeclamptic PatientsNot yet recruitingNCT06151457Not applicable
• Intensive Versus Standard Treatment for Hypotension on Maternal Hemodynamics in Preeclamptic PatientsNot yet recruitingNCT06151444Not applicable
• Epinephrine to Prevent Postintubation Collapse in Shocked ICU PatientsRecruitingNCT06115473Not applicable
• The Effect of Two Different Doses of Noradrenaline on Hypotension Caused by Spinal Anesthesia for Cesarean SectionRecruitingNCT06102382Not applicable
• Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During AnesthesiaRecruitingNCT06083948Phase 2/3
• Topical Adrenaline Versus Warm Saline Solution for Minimizing Intraperitoneal Bleeding During Caesarian Delivery for Placenta Previa / Accreta Spectrum ( PAS)RecruitingNCT06030479Not applicable
• Norepinephrine Prevent Post-induction Hypotension in High-risk PatientsNot yet recruitingNCT06028256Phase 4
• Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex DifferencesRecruitingNCT05997732Phase 4
• Early Initiated Vasopressor Therapy in the Emergency DepartmentRecruitingNCT05931601Phase 3
• The Construction and Application of Therapeutic System of Intelligent Decision-Oriented Hemodynamic Organized Therapy for Shock PatientsRecruitingNCT05886192Phase 4
• Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Anaesthesia Assessed by CardiometryNot yet recruitingNCT05860010Not applicable
• Early Administration of Norepinephrine in SepsisRecruitingNCT05836272Phase 4
• Comparison of Hemodynamic Results of Two Different Fluid ManagementsRecruitingNCT05733403Not applicable
• Efficacy of Anisodamine Hydrobromide Combined With Low-molecular-weight Heparin in the Treatment of Patients With SepsisRecruitingNCT05634057Not applicable
• Effects of Vasopressors on Cerebral Hemodynamics in Patients With Carotid Endarterectomy (MRI Part)Not yet recruitingNCT05414877Not applicable
• Sex Disparities in Hypoxic Vasodilation and Impact of ObesityRecruitingNCT05219799Early Phase 1
• Hot Flashes and Neurovascular Function in WomenRecruitingNCT05193968Not applicable
• Early Vasopressors in SepsisRecruitingNCT05179499Phase 3
• POHCA Resuscitation: Evaluation of IM EpinephrineRecruitingNCT05166343Phase 2/3
• Prophylactic Norepinephrine and Phenylephrine Infusion for Hemodynamic Effects in Patients With PreeclampsiaRecruitingNCT05035498Not applicable
• Preventing Cardiovascular Collapse With Vasopressors During Tracheal IntubationRecruitingNCT05014581Phase 3
• The GUARDIAN Trial - Vasopressor Sub-StudyEnrolling by invitationNCT04934748Phase 4
• Management of Shock in Children With SAM or Severe Underweight and DiarrheaRecruitingNCT04750070Phase 3
• Effects of Ephedrine, Phenylephrine, Norepinephrine and Vasopressin on Contractility of Human Myometrium and Umbilical Vessels: An In-vitro StudyRecruitingNCT04053478Not applicable
• Epinephrine Dose: Optimal Versus Standard Evaluation TrialRecruitingNCT03826524Phase 4
• Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass SurgeryRecruitingNCT03629418Not applicable
• Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep ApneaRecruitingNCT02630121Phase 4
• Vasoactive Drugs in Intensive Care UnitRecruitingNCT02118467Phase 4
• The PAIN (Pelvic Area Injection for Numbness) StudyTerminatedNCT05972681Phase 4Results posted
• Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus SurgeryCompletedNCT05867342Phase 4Results posted
• Management of Acute Pulmonary Hypertensive Crisis in Children With Known Pulmonary Arterial HypertensionCompletedNCT05439460Phase 4Results posted
• Epinephrine in the Pediatric Intensive Care Unit: A Dose-Effect TrialTerminatedNCT05327556Phase 2Results posted
• Subacromial Injection of Epinephrine Improves Visualization in Shoulder ArthroscopyCompletedNCT05244525Phase 4Results posted
• The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye AppearanceCompletedNCT04831047Phase 4Results posted
• Norepinephrine vs Phenylephrine During General AnesthesiaCompletedNCT04789330Phase 4Results posted
• Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:CompletedNCT04501861Phase 3Results posted
• Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy IndividualsCompletedNCT04207840Phase 4Results posted
• Effect of Epinephrine on Post-polypectomy PainCompletedNCT04065451Phase 4Results posted
• A Clinical Endpoint Bioequivalence Study of "Oxymetazoline Hydrochloride Cream"CompletedNCT03954444Phase 3Results posted
• The Impact of Retropubic Lidocaine vs Saline on Postoperative Urinary Retention Following Midurethral SlingCompletedNCT03913845Phase 4Results posted

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