Supplement
3-Hydroxybutyric Acid clinical trials
Also written Beta-hydroxybutyrate.
Keep track of what changes. Save the 3-Hydroxybutyric Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
21 studies that test it; most in 2023 (5)
| Year | Studies |
|---|---|
| 2011 | 1 |
| 2013 | 1 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 3 |
| 2023 | 5 |
| 2024 | 3 |
| 2025 | 2 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 21
University of Aarhus (5) · University of Pennsylvania (4) · Ohio State University (2) · University of Exeter (2) · The University of Texas Health Science Center at San Antonio (2) · University of South Carolina (1) · Gødstrup Hospital (1) · University of British Columbia (1)
Often tested with
Tested in the same studies.
Butylene glycol (10) · Butylene Glycols (10) · Ethanol (1) · Caffeine (1) · Citrulline (1) · Amino-acid, glucose, and electrolyte solution (1)
Studies
Open first, then newest update. How each study uses 3-Hydroxybutyric Acid is read from its arms, and is right about nine times in ten.
Testing it · 21
- Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use DisorderRecruitingPhase 2/3University of PennsylvaniaNCT06807918Written as Kenetik
- Effects of Pre-Run Nutritional Supplements During a Fixed-Pace 5 km Treadmill RunRecruitingNot applicableSt. Louis UniversityNCT07854223Written as Exogenous Ketone (Beta-Hydroxybutyrate)
- Variations in Ketone MetabolismRecruitingNot applicableOhio State UniversityNCT05924295Written as Ketone Supplement
- A Pilot Study Evaluating β-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal CancerRecruitingPhase 2Tao ZhangNCT07239466Written as β-hydroxybutyrate
- Effects of Ketone Supplement and Alcohol on Brain MetabolismActive, not recruitingPhase 2/3University of PennsylvaniaNCT06815237Written as Kenetik
- Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy VolunteersActive, not recruitingPhase 2/3University of PennsylvaniaNCT05551754Written as Ketone Supplement
- Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep RestrictionActive, not recruitingNot applicableOhio State UniversityNCT05519644Written as Ketone Supplement
- The Effect of Ketone Esters on Forearm Glucose MetabolismActive, not recruitingNot applicableUniversity of ExeterNCT06685913Written as Ketone supplement
- Effect of Nutritional Ketosis on Alcohol MetabolismActive, not recruitingPhase 2/3University of PennsylvaniaNCT06065657Written as Ketone Supplement
- Ketones, Muscle Metabolism, and SGLT2 Inhibitors - Protocol 1CompletedPhase 1The University of Texas Health Science Center at San AntonioNCT03560323Written as Beta-hydroxy-butyrate
- BHB and Cognition During Exercise-Heat StressCompletedNot applicableUniversity of South CarolinaNCT07010666Written as Beta-Hydroxybutyrate
- The Effect of a Ketone Drink on Blood Glucose Levels in People With Type 2 DiabetesCompletedNot applicableUniversity of ExeterNCT06324669Written as Ketone supplement
- Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory Capacity in Healthy SubjectsCompletedNot applicableGødstrup HospitalNCT05980858Written as Beta-hydroxybutyrate
- Exogenous Ketone Ester in Women with Polycystic Ovary Syndrome.CompletedNot applicableUniversity of AarhusNCT05762822Written as 3-OHB (KE4)
- The Effect of Different Ketone Supplements on β-OHB and Blood Glucose in Healthy IndividualsCompletedNot applicableUniversity of British ColumbiaNCT05273411Written as Beta-hydroxybutyric acid
- Effect of Ketogenic Diet on Glucose Metabolism and Energy Expenditure in Type 2 DiabetesCompletedNot applicableThe University of Texas Health Science Center at San AntonioNCT04791787Written as Beta-hydroxy butyrate
- Pre-meals of 3-hydroxybutyrate in Type 2 DiabetesCompletedNot applicableUniversity of AarhusNCT05581043Written as 3-hydroxybutyrate (3-OHB)
- Brain Ketone Metabolism in Type 1 DiabetesCompletedPhase 1Yale UniversityNCT02471040Written as Beta-hydroxybutyrate
- Keto Drinks as a Meal Primer in Patients With Type 2 DiabetesCompletedNot applicableUniversity of AarhusNCT05263401Written as 3-hydroxybutyrate
- Metabolic Effects of Exogenous 3-hydroxybutyrate in Patients With Type 1 Diabetes and Healthy ControlsCompletedNot applicableUniversity of AarhusNCT04656236Written as 3-hydroxybutyrate
See all 21 studies that test 3-Hydroxybutyric Acid →
Given in every arm · 1 — 3-Hydroxybutyric Acid is usual care beside what is tested
Codes
What other systems call 3-Hydroxybutyric Acid · ClinicalTrials.gg INT008756
- MeSH (NLM) D0201553-Hydroxybutyric AcidConfirmed NLM, Wikidata
- UNII (FDA) TZP12756793-HYDROXYBUTYRIC ACID, (+/-)-Confirmed NLM, Wikidata
- Wikidata Q2230923-hydroxybutyric acidConfirmed NLM, Wikidata
- DrugBank DB16506One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D020155 | 3-Hydroxybutyric Acid | Confirmed NLM, Wikidata |
| UNII (FDA) | TZP1275679 | 3-HYDROXYBUTYRIC ACID, (+/-)- | Confirmed NLM, Wikidata |
| Wikidata | Q223092 | 3-hydroxybutyric acid | Confirmed NLM, Wikidata |
| DrugBank | DB16506 | — | One source Wikidata |
Also registered as 3-hydroxybutyrate (UNII FG2UN5EP9V).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.