Ketosis clinical trials
The registry lists 181 studies for Ketosis across more than 10 countries. 38 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 97
- Status unknown
- 23
- Recruiting
- 23
- Not yet recruiting
- 13
- Terminated
- 9
- Active, not recruiting
- 7
Phase
- Phase 2
- 26
- Phase 1
- 10
- Phase 4
- 9
- Phase 3
- 6
- Early Phase 1
- 2
Where
- United States
- 62
- Canada
- 23
- Denmark
- 20
- United Kingdom
- 7
- Germany
- 6
- Belgium
- 6
Who runs them
University of Aarhus (14) · University of Pennsylvania (6) · University of British Columbia (5) · Université de Sherbrooke (5) · University of Colorado, Denver (4) · Western University, Canada (4) · Assistance Publique - Hôpitaux de Paris (3) · McGill University (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 181 — search for more.
- Ketosis, Immune Function and Metabolic Adaptation in Response to Short-term Fasting in Critical IllnessNot yet recruitingNCT07738536Not applicable1 country
- Endurance Trial: Ketone and Carbohydrate SupplementationRecruitingNCT07792876Not applicable1 country
- Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring.Not yet recruitingNCT07325201Phase 21 country
- Ketones for Opioid CravingRecruitingNCT07128524Phase 21 country
- Exogenous Ketone Supplementation in ICU DeliriumRecruitingNCT07364162Phase 21 country
- Combining Fasting and Fibre Interventions to Optimise Their Gut Microbiome-mediated Health BenefitsNot yet recruitingNCT07691736Not applicable1 country
- Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use DisorderNot yet recruitingNCT06807918Phase 2/31 country
- Recovery With Exogenous Ketones and AntipsychoticsRecruitingNCT07122531Not applicable1 country
- Variations in Ketone MetabolismRecruitingNCT05924295Not applicable1 country
- Specificities of Atypical Non AutoImmune Diabetes (ANAID) in the French West IndiesNot yet recruitingNCT075763741 country
- Prolonged Nasogastric Administration of Ketones in Decompensated Heart FailureRecruitingNCT07527156Phase 41 country
- Effects of Ketone Supplementation on Acute Alcohol WithdrawalEnrolling by invitationNCT06173973Phase 2/31 country
- SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research PlanRecruitingNCT05057806Early Phase 11 country
- Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac FunctionRecruitingNCT06078683Not applicable1 country
- Effects of Ketone Supplement and Alcohol on Brain MetabolismRecruitingNCT06815237Phase 2/31 country
- Hemodynamic Effects of Ketone Esters in Patients With Sepsis Induced CardiomyopathyNot yet recruitingNCT06952140Not applicable
- Evaluation of a Novel Insulin Sensitizer in People With Type 1 DiabetesRecruitingNCT07186660Phase 21 country
- Ketones, SGLT2, HFrEFRecruitingNCT06229678Early Phase 11 country
- Undiluted and Diluted NutritionNot yet recruitingNCT07352150Not applicable1 country
- Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers (K-SLEEP)RecruitingNCT07224074Phase 11 country
- Nutritional Ketosis: a Novel Metabolic Strategy to Treat Lymphedema Patients?RecruitingNCT03991897Not applicable1 country
- Evaluating Safe Ketone Thresholds To Minimise Ketosis in People With Type 1 Diabetes Using DapagliflozinNot yet recruitingNCT07225465Phase 21 country
- Investigating the Evolutionary Impact of Metabolic Flexibility on Physical Activity-Dependent BDNF and Cognition: Insights From the Val66Met PolymorphismNot yet recruitingNCT07218497Phase 11 country
- Effects of Moderate Carbohydrate Consumption on Metabolic and Obstetric Outcomes in Pregnant Women With Insulin-treated Diabetes- A Randomized Controlled TrialRecruitingNCT06355154Not applicable1 country
- Chronic Exogenous Ketosis in HFpEFEnrolling by invitationNCT06937320Phase 21 country
- Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use DisorderRecruitingNCT06559995Phase 2/31 country
- Can the Addition of Pioglitazone to SGLT2 Inhibitor in Type 1 Diabetic Patients Amplify the Decrease in HbA1c and Prevent the Increase in Plasma Ketone Concentration?Not yet recruitingNCT06922656Phase 43 countries
- Serum Ferritin and Prognosis of DKARecruitingNCT067483651 country
- Validation and Testing of a Novel Continuous Glucose and Continuous Ketone Monitoring Device in Healthy VolunteersRecruitingNCT068779751 country
- The Effect of Acute Exogenous Oral Ketone Supplementation on Immune Cells Function and Immune Cells Histone Β-hydroxybutyrylationRecruitingNCT06590623Not applicable1 country
- Effects of Ketosis on Brain Function in Patients With T1DMRecruitingNCT04219709Not applicable1 country
- Children with Diabetic KetoacidosisNot yet recruitingNCT06599203
- Electrolyte Balance Effects of Sterofundin Versus Normal Saline in Diabetic KetoacidosisRecruitingNCT06399510Not applicable1 country
- Acute Effects of Exercise Combined With Ketone Ester SupplementNot yet recruitingNCT06365957Not applicable
- The Impact of Different Carbohydrate Restriction After a Gastric Bypass on the Ketosis and KetoacidosisRecruitingNCT06338969Not applicable1 country
- Risk Factors and Outcomes of Acute Kidney Injury in Patients With Diabetic Ketoacidosis at Sohag University Hospital.Not yet recruitingNCT05867797
- Ketonemia Through Menstrual CycleRecruitingNCT052344111 country
- Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial ImagingRecruitingNCT04275453Phase 1/21 country
- The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune ResponseCompletedNCT05558488Not applicable1 country
- Impact of Exogenous Ketones on Sleep ApneaWithdrawnNCT06687655Phase 1/21 country
- Effects of Exogenous Ketosis on Proteinuria and Renal FunctionCompletedNCT06867471Not applicable1 country
- Ketones in Heart Failure With Reduced Ejection FractionCompletedNCT06195982Phase 21 country
- Ketogenic Diet for Post-Traumatic Stress Disorder (PTSD)CompletedNCT07415590Not applicable1 country
- Weight Reduction With the Low-Insulin-Method - Self Monitoring of Breath AcetoneActive, not recruitingNCT06745362Not applicable1 country
- Effect of Ketosis on Pain and Quality of Life in Patients With LipedemaCompletedNCT04632810Not applicable1 country
- Do Ketone Drinks Improve Immune, Metabolic and Cognitive Health in Older AdultsCompletedNCT06068803Not applicable1 country
- Impact of Exogenous Ketones on Sleep Disruption in Vulnerable PopulationsSuspendedNCT06655649Phase 11 country
- Evaluation of the Ketogenic Diet to Improve Post Operative Cognitive Decline in Cardiac SurgeryWithdrawnNCT06480708Not applicable1 country
- Strategies to Augment Ketosis: Optimization of Ketone Delivery StrategiesActive, not recruitingNCT05501366Not applicable1 country
- Exogenous Ketosis in a Fed and a Fasted StateCompletedNCT06320522Not applicable1 country