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Ketosis clinical trials

The registry lists 218 studies for Ketosis across more than 10 countries. 50 are recruiting or about to start. 89 of them are mainly about Ketosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its narrower condition Diabetic Ketoacidosis too: 289 studies, 66 open.

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Status

Completed
119
Recruiting
30
Status unknown
27
Not yet recruiting
18
Active, not recruiting
11
Withdrawn
5

Phase

Phase 2
27
Phase 1
17
Phase 3
8
Phase 4
5
Early Phase 1
4

Where

United States
67
Canada
40
Denmark
26
Belgium
12
Germany
9
United Kingdom
9

Who runs them

Université de Sherbrooke (18) · University of Aarhus (16) · University of British Columbia (12) · Johns Hopkins University (8) · KU Leuven (7) · Ohio State University (5) · McGill University (5) · University of Pennsylvania (5)

What is being tested here

Drugs under test in Ketosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Butylene glycol539
Butylene Glycols539
Beta-hydroxybutyrate-1,3-butanediol monoester3017
(R)-3-hydroxybutyl (R)-3-hydroxybutyrate3011
3-Hydroxybutyric Acid239
Dapagliflozin204
Empagliflozin203
Pioglitazone101
Carbohydrates101
Ketones004

Drug classes tested here SGLT2 inhibitors 4 open

Coming up

5phase 3 studies under way
24studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 30 Ketosis studies recruiting now, 6 (20%) set no upper age limit and 22 (73%) stop at 75 or younger. 1 (3%) take children under 18. 3 (10%) are for women only and 2 (7%) for men only; 8 (27%) take healthy volunteers.

Recruiting studies that take each age, of 30
AgeWomenMen
100 (0%)0 (0%)
1823 (77%)22 (73%)
3026 (87%)26 (87%)
4025 (83%)24 (80%)
5018 (60%)18 (60%)
6517 (57%)16 (53%)
7510 (33%)10 (33%)
856 (20%)6 (20%)

Across all 218 studies, recruiting or not: 57% stop at 75 or younger and 49% at 65; 9% take children; 5% are for women only and 13% for men only; 46% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Ketosis studies take

Of 103 interventional studies with no phase under Ketosis, half reached primary completion within 14 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase14 mo7–24 · 103 studies—14 mo7–24 · 99 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting4

Results posted1

Newly registered3

Studies

Recruiting first, then most recently updated. Showing 50 of 218. Browse all 218 → or search them.