Alcohol Drinking clinical trials
The registry lists 701 studies for Alcohol Drinking across more than 10 countries. 133 are recruiting or about to start. 325 of them are mainly about Alcohol Drinking (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 3 narrower conditions too, such as Binge Drinking: 808 studies, 158 open.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Yale University (32) · University of Washington (24) · Brown University (22) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (20) · Boston Medical Center (15) · University of Pennsylvania (13) · University of Michigan (12) · VA Office of Research and Development (11)
What is being tested here
Drugs under test in Alcohol Drinking studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ethanol | 3 | 1 | 23 |
| Semaglutide | 1 | 0 | 2 |
| Mavoglurant | 1 | 0 | 2 |
| Dextromethorphan | 1 | 0 | 2 |
| Guanfacine | 1 | 0 | 2 |
| Brexanolone | 1 | 0 | 1 |
| BLA80 | 1 | 0 | 1 |
| Spironolactone | 1 | 0 | 1 |
| Lactobacillus reuteri | 1 | 0 | 1 |
| Blueberry extract | 1 | 0 | 1 |
Drug classes tested here GLP-1 receptor agonists 1 open · Opioid antagonists 11
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy Volunteers · Phase 3 · University of Pennsylvania
- Dec 2026Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder · Phase 3 · University of Pennsylvania
- Dec 2026Ketone Ester Intervention in Alcohol Use Disorder · Phase 3 · University of Pennsylvania
- Nov 2026Clinical Effectiveness of a Motivational Interviewing-Based Conversational Mobile Application for High-Risk Drinkers · Yonsei University
- Nov 2026Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building · University of Rhode Island
- Nov 2026Just-In-Time Intervention to Reduce Alcohol-Facilitated Intimate Partner Violence Perpetration · Georgia State University
- Nov 2026CPNF Intervention Development and Testing · University of Washington
- Nov 2026Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC · University Hospitals Cleveland Medical Center
- Nov 2026Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of High School · University of Washington
- Dec 2026Accountability Support Through Peer-Inspired Relationships and Engagement (ASPIRE) Trial · Stanford University
Who these studies take
Of the 97 Alcohol Drinking studies recruiting now, 37 (38%) set no upper age limit and 52 (54%) stop at 75 or younger. 10 (10%) take children under 18. 9 (9%) are for women only and 4 (4%) for men only; 47 (48%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (2%) | 2 (2%) |
| 18 | 55 (57%) | 50 (52%) |
| 30 | 66 (68%) | 61 (63%) |
| 40 | 64 (66%) | 57 (59%) |
| 50 | 62 (64%) | 57 (59%) |
| 65 | 52 (54%) | 47 (48%) |
| 75 | 44 (45%) | 39 (40%) |
| 85 | 42 (43%) | 37 (38%) |
Across all 701 studies, recruiting or not: 56% stop at 75 or younger and 51% at 65; 16% take children; 7% are for women only and 5% for men only; 54% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Alcohol Drinking studies take
Of 34 phase 1 interventional studies under Alcohol Drinking, half reached primary completion within 37 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 37 mo21–48 · 34 studies | — | 40 mo23–49 · 32 studies |
| Phase 2 | 43 mo23–62 · 24 studies | — | — |
| Interventional, no phase | 24 mo10–45 · 336 studies | — | 24 mo11–45 · 328 studies |
| Observational | 56 mo21–138 · 39 studies | — | 56 mo21–138 · 38 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting4
- Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use OutcomesNov 4, 2026NCT07772960
- Precision Microbiota Interventions for Senoreduction TrialOct 29, 2026NCT07462767
- MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience EducationOct 22, 2026NCT06553196
- Maternal Outcomes: Mood, Alcohol Use, and Depressive SymptomsOct 13, 2026NCT07485036
Results posted1
- Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol UseOct 15, 2026NCT07010601
Newly registered4
- Letter-Writing Add-On to Brief Motivational Intervention for Alcohol UseNov 9, 2026NCT07926880
- Evaluation of Purple TownNov 5, 2026NCT07919639
- HC-HMP: Healthy Choices Implementation TrialNov 3, 2026NCT07911644
- FLOW: Influence of the Menstrual Cycle on Alcohol Use in WomenNov 2, 2026NCT07910643
Studies
Recruiting first, then most recently updated. Showing 50 of 701. Browse all 701 → or search them.
- Nicotinic Receptor Genetic Variation and Alcohol RewardRecruitingNCT03294460Phase 11 country
- Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use ProblemsRecruitingNCT06593652Not applicable1 country
- Letter-Writing Add-On to Brief Motivational Intervention for Alcohol UseNot yet recruitingNCT07926880Not applicable1 country
- Spironolactone in Alcohol Use Disorder (SAUD)RecruitingNCT05807139Phase 11 country
- HC-HMP: Healthy Choices Implementation TrialNot yet recruitingNCT07911644Not applicable1 country
- Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use OutcomesRecruitingNCT07772960Phase 11 country
- FLOW: Influence of the Menstrual Cycle on Alcohol Use in WomenNot yet recruitingNCT079106431 country
- PNF RCT to Decrease Alcohol Use and Increase HIV PreventionNot yet recruitingNCT07731932Not applicable1 country
- Precision Microbiota Interventions for Senoreduction TrialRecruitingNCT07462767Phase 1/21 country
- Adjunctive Motivational Alcohol Intervention to Prevent IPVRecruitingNCT05287711Not applicable1 country
- ChangeGradients: Promoting Adolescent Health Behavior ChangeRecruitingNCT04110756Not applicable1 country
- MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience EducationRecruitingNCT06553196Not applicable1 country
- Acceptance and Commitment Therapy for HIV+ Hazardous DrinkersRecruitingNCT06648629Not applicable1 country
- Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening VisitsNot yet recruitingNCT07799467Not applicable1 country
- A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their PartnersRecruitingNCT05619185Not applicable1 country
- Maternal Outcomes: Mood, Alcohol Use, and Depressive SymptomsRecruitingNCT07485036Not applicable1 country
- Parent-Focused Alcohol Prevention Program for Hispanic Families in Faith-Based SettingsNot yet recruitingNCT07869550Not applicable1 country
- Reducing Cardiovascular Risks: The Role of Alcohol UseRecruitingNCT07783061Not applicable1 country
- Cannabis' Impact on Alcohol ConsumptionRecruitingNCT05389930Phase 21 country
- Evaluation of a Trauma-Informed Partner Violence Intervention ProgramEnrolling by invitationNCT06803043Not applicable1 country
- HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)RecruitingNCT06513819Phase 11 country
- Virtual Reality (VR-GINSO) as an Complement to Intervention for Alcohol and Cannabis Use in Youth in Residential CareRecruitingNCT07834606Not applicable1 country
- Pregnenolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding StudyNot yet recruitingNCT06580444Phase 2
- Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient StudyRecruitingNCT06335407Phase 11 country
- Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent MechanismRecruitingNCT07824089Not applicable1 country
- Brief Motivational Interviewing +/- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary CareRecruitingNCT07059078Not applicable1 country
- The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)RecruitingNCT06070649Phase 11 country
- Alcohol, Breast Cancer, and MetabolismRecruitingNCT07779967Not applicable1 country
- Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMCRecruitingNCT068648191 country
- Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCTRecruitingNCT05288790Phase 21 country
- Partnering to Enhance Emerging Adults' Response to ProgramsRecruitingNCT06115252Not applicable1 country
- Efficacy of the Proactive Automatized Lifestyle InterventionRecruitingNCT07441603Not applicable1 country
- Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy DrinkersRecruitingNCT06136195Phase 11 country
- Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk BehaviorNot yet recruitingNCT07769580Not applicable1 country
- Smartphone-based Intervention for Young Adults With ADHDRecruitingNCT07654205Not applicable1 country
- Telephone-Based Acceptance and Commitment Therapy for Young Adult Hazardous DrinkersNot yet recruitingNCT07621822Not applicable
- CARS: Cannabis and Alcohol Reduction StudyRecruitingNCT05486234Not applicable1 country
- Drinking, Acetate, and StressRecruitingNCT06584448Not applicable1 country
- Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)RecruitingNCT06259916Not applicable1 country
- Understanding the Associations Between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse Among Emerging AdultsRecruitingNCT06976528Not applicable1 country
- Effects of Ketogenic Diet on Alcohol IntoxicationRecruitingNCT07602270Not applicable1 country
- Whole Selves User Testing and Feasibility StudyNot yet recruitingNCT06392542Not applicable1 country
- Alcohol and "Heat of the Moment" Sexual Decision MakingRecruitingNCT05729256Not applicable1 country
- Alcohol & Men's Sexual Risk BehaviorsRecruitingNCT06158880Not applicable1 country
- Wellness, Alcohol, Vitals, and EmotionsRecruitingNCT06982443Not applicable1 country
- CPNF Intervention Development and TestingEnrolling by invitationNCT07036198Not applicable1 country
- Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult CouplesNot yet recruitingNCT06422299Not applicable
- Mentor Moms+ StudyRecruitingNCT06962592Not applicable1 country
- mHealth-supported Skills Training for Alcohol-Related SuicidalityEnrolling by invitationNCT05847504Not applicable1 country
- Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV CareRecruitingNCT05241990Not applicable1 country