Photophobia clinical trials
The registry lists 43 studies for Photophobia across more than 10 countries. 13 are recruiting or about to start. 8 of them are mainly about Photophobia (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.
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Who runs them
Pfizer (8) · Ohio State University (2) · University of Utah (2) · Arizona State University (2) · University of Michigan (1) · Bradley Katz (1) · VA Office of Research and Development (1) · Northumbria University (1)
What is being tested here
Drugs under test in Photophobia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Rimegepant | 3 | 3 | 4 |
| Lithium Carbonate | 1 | 0 | 1 |
| Zavegepant | 0 | 3 | 3 |
| Atropine | 0 | 0 | 1 |
| Nitisinone | 0 | 0 | 1 |
| Erenumab | 0 | 1 | 1 |
Drug classes tested here CGRP receptor antagonists 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury · VA Office of Research and Development
- Dec 2026Effect of Fixation Training With Colored Light Targets on Traumatic Brain Injury-Associated Photophobia · Ohio State University
- Dec 2026Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity · University of Alabama at Birmingham
- Mar 2027Light Exposure, Migraine Outcomes, and Sleep Quality · Arizona State University
Who these studies take
Of the 10 Photophobia studies recruiting now, 2 (20%) set no upper age limit and 6 (60%) stop at 75 or younger. 3 (30%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (30%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (30%) | 3 (30%) |
| 18 | 7 (70%) | 7 (70%) |
| 30 | 7 (70%) | 7 (70%) |
| 40 | 7 (70%) | 7 (70%) |
| 50 | 6 (60%) | 6 (60%) |
| 65 | 5 (50%) | 5 (50%) |
| 75 | 4 (40%) | 4 (40%) |
| 85 | 2 (20%) | 2 (20%) |
Across all 43 studies, recruiting or not: 40% stop at 75 or younger and 37% at 65; 21% take children; 0% are for women only and 0% for men only; 30% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 43 of 43. search them.
- Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of MigraineRecruitingNCT04743141Phase 33 countries
- Randomized Study in Children and Adolescents With Migraine: Acute TreatmentRecruitingNCT04649242Phase 39 countries
- Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric SubjectsRecruitingNCT05156398Phase 37 countries
- Objectively Diagnose and Monitor Treatment of Light SensitivityRecruitingNCT03694626Not applicable1 country
- Examining Lithium's Mechanism in Bipolar DisorderNot yet recruitingNCT07750925Not applicable1 country
- Use of Tinted Contact Lenses for Concussion-Related Light SensitivityRecruitingNCT07223086Not applicable1 country
- Effect of Fixation Training With Colored Light Targets on Traumatic Brain Injury-Associated PhotophobiaRecruitingNCT07606300Not applicable1 country
- Comparison Between Spectacles and Contact LensesNot yet recruitingNCT06905912Not applicable1 country
- Light Exposure, Migraine Outcomes, and Sleep QualityRecruitingNCT07476053Not applicable1 country
- Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual StimuliRecruitingNCT06961864Not applicable1 country
- Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain InjuryRecruitingNCT06109909Not applicable1 country
- Migraine Headache Mitigation Utilizing AvuluxNot yet recruitingNCT06149000Not applicable
- Eye Movement Behaviour and Pupil Size in Natural Outdoor and Indoor ScenesRecruitingNCT05971238Not applicable1 country
- Impact of Optimized White Light on Visual Discomfort, Headache Intensity, and Cognitive Performance Among Those With MigraineCompletedNCT07898722Not applicable1 country
- Functionally Validated Structural Endpoints for Early AMDCompletedNCT041126671 country
- Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine PreventionCompletedNCT05207865Phase 41 country
- Impact Of Everyday Light Exposure Patterns On HealthCompletedNCT06908395Not applicable1 country
- Improving Glare and Visual Comfort for Patients With Visual ImpairmentWithdrawnNCT05829135Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine PreventionTerminatedNCT04804033Phase 2/31 country
- Performance and Tolerability of the Medical Device LACRIACTCompletedNCT06159569Not applicable1 country
- Acute Treatment Trial in Adult Subjects With MigrainesCompletedNCT03872453Phase 2/31 country
- Mindfulness Based Cognitive Therapy Modified for Visual Symptoms (MBCT-vision)CompletedNCT04184726Not applicable1 country
- Randomized Trial in Adult Participants With Acute MigrainesCompletedNCT04571060Phase 31 country
- An Open-label, Intermediate Size, Expanded Access Study of BHV-3000 in the Acute Treatment of MigraineNo longer availableNCT03934086
- Biomarker for Cystinosis Disease: BioCystinosis (BioCystinosis)WithdrawnNCT028375233 countries
- Side Effects of Atropine (SEA) StudyCompletedNCT03593044Phase 1/21 country
- Spectacle Tints and Thin-Films for MigraineTerminatedNCT02720211Not applicable1 country
- Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Child and Adolescent Patients With MigraineTerminatedNCT01942486Not applicable1 country
- How Can we Treat Photophobia in MigraineCompletedNCT05369910Not applicable
- Clinical Evaluation of Morcher Artificial Iris DiaphragmsCompletedNCT00812708Not applicable1 country
- Long-Term Study of Nitisinone to Treat AlkaptonuriaCompletedNCT00107783Phase 21 country
- Light at Night StudyTerminatedNCT04251234Not applicable1 country
- Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical HeterophoriaTerminatedNCT00785135Not applicable1 country
- Validation of a Questionnaire for Allodynia in Migraine.Status unknownNCT045806411 country
- Study of Quality of Life in Subjects With Chronic or High-frequency Episodic Migraine and Associated Comorbidities Treated With ErenumabWithdrawnNCT04114630Phase 31 country
- Tolerance to Light for Patients Suffering From KeratitisCompletedNCT03586505Not applicable1 country
- The Effect of Eyemasks on Neonatal Stress Following Dilated Retinal ExaminationCompletedNCT03824782Not applicable1 country
- Functional MRI Study of Cortical Modifications to Light Stimulation in Patients With PhotophobiaStatus unknownNCT03464357Not applicable1 country
- The Head Injury-associated Photosensitivity and Pupillary Function (HIPP) StudyCompletedNCT019425641 country
- Study to Determine the Efficacy and Safety of ELS-M11 in Acute MigraineCompletedNCT02057315Phase 1/21 country
- Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients With MigraineCompletedNCT01828684Not applicable1 country
- "Eye Protection After Mydriatic Use for ROP Screening: Impact on Vitals Signs and Pain Scores"CompletedNCT01860534Not applicable1 country
- An Efficacy Study of a Single Dose Treatment of PRO-513 for Subjects Suffering a Migraine AttackCompletedNCT00330850Phase 31 country