An observational study in Takotsubo Cardiomyopathy and Myocardial Infarction, sponsored by University of Aberdeen. Recruiting at 1 site in United Kingdom. Per ClinicalTrials.gov, last updated 2026-09-09.
Sponsored by University of Aberdeen · Observational
Acute stress-induced (Takotsubo cardiomyopathy) presents like a heart attack and is triggered by intense emotional or physical stress. Although coronary arteries are unobstructed, it has been suggested that the risk of death is similar to a myocardial infarction. The purpose of the STARR study is to identify all cases of Takotsubo in Scotland since 2010 and assess its epidemiology and outcomes.
Public Health Scotland will identify all patients centrally coded under codes I42.8 (Other cardiomyopathies), I42.9 (Cardiomyopathy, unspecified) and I51.8 (Other ill-defined heart diseases), using the Community Health Index (CHI) numbers from January 2010. All identified CHI numbers will be thereafter cross-checked with their clinical data at participating health boards to confirm a diagnosis of takotsubo cardiomyopathy and a registry of all confirmed Takotsubo cases will be established.
Clinical data will be collected for all Takotsubo patients retrospectively and prospectively. This will be compared to two contemporaneous gender and age matched control populations:
Electronic data linkage will be performed by Public Health Scotland to assess outcomes, prescribing and scores of prediction.
Patients diagnosed with Takotsubo cardiomyopathy in Scotland since 2010
Exclusion Criteria:
All patients diagnosed with Takotsubo cardiomyopathy in Scotland since 2010.
An equal number of myocardial infarction patients in NHS Grampian since 2010.
Mortality and morbidity of takotsubo syndrome
To use a nation-wide cohort (and matched national-wide control populations) to establish the all-cause mortality and consequent all cause hospitalisation rates
Time frame: 13 years
Specific causes of mortality and morbidity of takotsubo syndrome
To use a nation-wide cohort (and matched national-wide control populations) to establish the specific causes of mortality and morbidities requiring subsequent hospitalisation
Time frame: 13 years
Plan to share: No
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University of Aberdeen